Source: Fox News
Posted: November 20, 2006
This post is a feature that examines and explains adult stem cell research.
Tuesday, November 21, 2006
'Cancer stem cells' behind colon cancer: research
Source: Agence-France Presse (AFP)
Date: November 21, 2006 12:39 AM ET
Summary:
A few bad stem cells may be responsible for most cancers, Canadian scientists looking into the root causes of colon cancer reported, indicating hope for better cancer treatments in the next decade. Abnormal stem cells have also been identified as the source of the disease in certain types of leukemia, as well as in breast and brain tumors. Researchers hope the findings may lead to better cancer treatments that target these stem cells.
Date: November 21, 2006 12:39 AM ET
Summary:
A few bad stem cells may be responsible for most cancers, Canadian scientists looking into the root causes of colon cancer reported, indicating hope for better cancer treatments in the next decade. Abnormal stem cells have also been identified as the source of the disease in certain types of leukemia, as well as in breast and brain tumors. Researchers hope the findings may lead to better cancer treatments that target these stem cells.
Monday, November 20, 2006
Advance helps explain stem cell behavior
Source: Oregon State University
Date: November 20, 2006
Summary:
Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal.
Date: November 20, 2006
Summary:
Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal.
Colon cancer stem cells identified
Source: The Scientist
Posted: 20th November 2006 02:21 PM GMT
Summary:
Scientists have identified a population of human colon cancer stem cells that can initiate tumor growth and differentiate into mature tumors
Posted: 20th November 2006 02:21 PM GMT
Summary:
Scientists have identified a population of human colon cancer stem cells that can initiate tumor growth and differentiate into mature tumors
Stem Cells May Trigger Tumors
Source: Medical News Today
Posted 20 November 2006 - 10:00am (PST)
Summary:
In two separate studies published in the journal Nature, scientists discovered that colon (cancer) stem cells were causing colon cancer tumors in mice. The researchers say cancer treatments will have to target cancer stem cells.
Commentary: This finding could provide scientists and researchers with new strategies to develop cancer treatments.
Posted 20 November 2006 - 10:00am (PST)
Summary:
In two separate studies published in the journal Nature, scientists discovered that colon (cancer) stem cells were causing colon cancer tumors in mice. The researchers say cancer treatments will have to target cancer stem cells.
Commentary: This finding could provide scientists and researchers with new strategies to develop cancer treatments.
Cancer stem cells start tumors in mice
Source: Reuters
Posted: November 20, 2006 8:23am ET
Summary:
Stem cells -- the master cells that give rise to all the blood and tissue in the body -- may also be responsible for tumors, according to two separate studies. Canadian and Italian researchers both found that specialized colon cancer stem cells appeared to be the sources of colon cancer tumors in mice. Their findings, published in the journal Nature, support the belief that future cancer treatments will have to home in on cancer stem cells.
Posted: November 20, 2006 8:23am ET
Summary:
Stem cells -- the master cells that give rise to all the blood and tissue in the body -- may also be responsible for tumors, according to two separate studies. Canadian and Italian researchers both found that specialized colon cancer stem cells appeared to be the sources of colon cancer tumors in mice. Their findings, published in the journal Nature, support the belief that future cancer treatments will have to home in on cancer stem cells.
Stem cells core of more cancers: New discoveries that pinpoint bad seeds leading to a major redirection of research
Source: The Globe and Mail
Posted: November 20, 2006 3:47 AM EST
Summary:
New discoveries about the basic biology of cancer are revealing that the root cause of the disease is not tumors, as had long been previously thought, but stem cells that become cancerous. In a new study published the journal Nature, researchers have found that abnormal stem cells are the source of colon cancer. The finding is leading scientists to change the focus of their research to target the cells.
Commentary: This finding is significant, as it could provide physicians with new strategies to detect cancers early and treat them effectively before they spread.
Posted: November 20, 2006 3:47 AM EST
Summary:
New discoveries about the basic biology of cancer are revealing that the root cause of the disease is not tumors, as had long been previously thought, but stem cells that become cancerous. In a new study published the journal Nature, researchers have found that abnormal stem cells are the source of colon cancer. The finding is leading scientists to change the focus of their research to target the cells.
Commentary: This finding is significant, as it could provide physicians with new strategies to detect cancers early and treat them effectively before they spread.
One step closer to cancer's Holy Grail: Treating 'stem cells' like treating root of weed, scientist proclaims
Source: Toronto Star
Posted: November 20, 2006. 05:17 AM
Summary:
Scientists have found strong evidence that only a small proportion of cells drive the formation of tumors causing to colon cancer. Colon cancer is the fourth type of cancer in which stem cells have been found to be its root cause, lending credibility to the idea that the cells may be the source of all cancers. The discovery could lead to earlier dection and produce more effective treatments for the disease.
Posted: November 20, 2006. 05:17 AM
Summary:
Scientists have found strong evidence that only a small proportion of cells drive the formation of tumors causing to colon cancer. Colon cancer is the fourth type of cancer in which stem cells have been found to be its root cause, lending credibility to the idea that the cells may be the source of all cancers. The discovery could lead to earlier dection and produce more effective treatments for the disease.
Another Boost For Stem Cell Research
Source: University of New South Wales
Posted: November 20, 2006
Summary:
Australian researchers have proven that tumours can be prevented from forming when embryonic stem cells are transplanted by placing the embryonic cells inside microcapsules made from a product of seaweed, called alginate. The discovery removes an obstacle to human embryonic stem cell research, and could ultimately lead to safer embryonic stem cell treatments for patients.
Posted: November 20, 2006
Summary:
Australian researchers have proven that tumours can be prevented from forming when embryonic stem cells are transplanted by placing the embryonic cells inside microcapsules made from a product of seaweed, called alginate. The discovery removes an obstacle to human embryonic stem cell research, and could ultimately lead to safer embryonic stem cell treatments for patients.
Nerve Fibers Need Specific Growth Factor Chemical To Form Connections Within The Brain
Source: University of California - Irvine
Date: November 20, 2006
Summary:
A discovery on how neural circuitry develops to aid proper cerebral cortex activity may help explain the memory and cognitive decline seen in Alzheimer's disease patients – a discovery that could point toward potential treatments, according to UC Irvine scientists.
Date: November 20, 2006
Summary:
A discovery on how neural circuitry develops to aid proper cerebral cortex activity may help explain the memory and cognitive decline seen in Alzheimer's disease patients – a discovery that could point toward potential treatments, according to UC Irvine scientists.
Sunday, November 19, 2006
Colon cancer appears to arise from cancer stem cells, mice study shows
Source: Canadian Press
Posted: November 19, 2006 5:00 PM
Summary:
Scientists have discovered that colon cancer arises from stem cells specific to the tumour after human colorectal tumour cells were implanted in mice. The finding could lead to more targeted treatments to prevent recurrence of the disease.
Posted: November 19, 2006 5:00 PM
Summary:
Scientists have discovered that colon cancer arises from stem cells specific to the tumour after human colorectal tumour cells were implanted in mice. The finding could lead to more targeted treatments to prevent recurrence of the disease.
Scientists Regenerate Wing In Chick Embryo
Source: Salk Institute
Date: November 19, 2006
Summary:
Most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo -- a species not known to be able to regrow limbs - suggesting that the potential for such regeneration exists innately in all vertebrates, including humans.
Date: November 19, 2006
Summary:
Most animals have lost the ability to replace missing limbs. Now, a research team at the Salk Institute for Biological Studies has been able to regenerate a wing in a chick embryo -- a species not known to be able to regrow limbs - suggesting that the potential for such regeneration exists innately in all vertebrates, including humans.
Saturday, November 18, 2006
Stem cells treat wasted muscles: Dogs with muscular dystrophy walk better after injections.
Source: Nature
Date: 15 November 2006
Summary:
An infusion of stem cells scraped from blood vessels has helped dogs with a form of muscular dystrophy to walk more normally, perhaps heralding a treatment for the human disease.
Date: 15 November 2006
Summary:
An infusion of stem cells scraped from blood vessels has helped dogs with a form of muscular dystrophy to walk more normally, perhaps heralding a treatment for the human disease.
Neural stem cell growth stimulated
Source: Los Angeles Times
Date: November 18, 2006
Summary:
Researchers have found a way to stimulate the growth of neural stem cells in the brains of adult mice, potentially eventually utilizing the the brain's natural capacity for repair to help people with diseases such as Alzheimer's.
Date: November 18, 2006
Summary:
Researchers have found a way to stimulate the growth of neural stem cells in the brains of adult mice, potentially eventually utilizing the the brain's natural capacity for repair to help people with diseases such as Alzheimer's.
Friday, November 17, 2006
Targeting Leukemic Stem Cells By BCL-2 Inhibition
Source: University of Texas M. D. Anderson Cancer Center
Date: November 17, 2006
Summary:
Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment.
The drug was powerful in its own right, the researchers say, but they found that some AML cells were themselves resistant to ABT-737, so they added another drug that knocked out this secondary resistance. Together, these agents may provide a powerful therapy against AML, and could form the basis of a new way to treat the cancer, say the scientists, whose study was published in the November 14 issue of the journal, Cancer Cell.
Date: November 17, 2006
Summary:
Researchers at The University of Texas M. D. Anderson Cancer Center have found, in laboratory studies, that the experimental drug ABT-737 which has shown promise in some cancers, can destroy acute myeloid leukemia (AML) blast, progenitor and even stem cells that are often resistant to standard chemotherapy treatment.
The drug was powerful in its own right, the researchers say, but they found that some AML cells were themselves resistant to ABT-737, so they added another drug that knocked out this secondary resistance. Together, these agents may provide a powerful therapy against AML, and could form the basis of a new way to treat the cancer, say the scientists, whose study was published in the November 14 issue of the journal, Cancer Cell.
Scripps researchers find new method for eye repair
Source: San Diego Daily Transcript via Yahoo! News
Date: November 17, 2006
Summary:
Researchers at The Scripps Institute in San Diego have found a way to repair and normalize blood vessels in the eyes of mice using stem cells obtained from bone marrow. The findings could have implications for developing human treatments for a certain type of eye diseases, such as a type of blindness that can occur in people with diabetes called diabetic retinopathy or retinopathy of prematurity.
Date: November 17, 2006
Summary:
Researchers at The Scripps Institute in San Diego have found a way to repair and normalize blood vessels in the eyes of mice using stem cells obtained from bone marrow. The findings could have implications for developing human treatments for a certain type of eye diseases, such as a type of blindness that can occur in people with diabetes called diabetic retinopathy or retinopathy of prematurity.
Bioheart, Inc. Expands Clinical Trials Of Adult Myogenic Stem Cell Treatment For Heart Attack And Advanced Heart Failure Patients
Source: Bioheart, Inc.
Date: November 17, 2006
Summary:
Bioheart, Inc., a biotechnology company focused on the development of innovative cell therapies designed to repair areas of damaged muscle tissue in a patient's heart and improve cardiac function, is expanding its United States and European clinical trials of its MyoCell(TM) adult myogenic (muscle) stem cell composition and MyoCath(R) needle-injection catheter product candidates.
Date: November 17, 2006
Summary:
Bioheart, Inc., a biotechnology company focused on the development of innovative cell therapies designed to repair areas of damaged muscle tissue in a patient's heart and improve cardiac function, is expanding its United States and European clinical trials of its MyoCell(TM) adult myogenic (muscle) stem cell composition and MyoCath(R) needle-injection catheter product candidates.
Stem cell hope for chemotherapy patients
Source: Apollo Life Sciences
Date: November 17, 2006
Summary:
In a world first, Apollo Life Sciences has revealed that two of its human proteins, which are wholly derived from human cells, are up to 53% faster in generating vital white blood cells used in the treatment of chemotherapy patients. This means cancer patients who normally have to wait for up to three weeks for white blood cell levels to regenerate before embarking on subsequent courses of chemotherapy can access potentially life saving treatments earlier. In the future, it is anticipated that patients will benefit from quicker recovery times from chemotherapy, as well as avoiding a host of side effects involved in their treatment.
Date: November 17, 2006
Summary:
In a world first, Apollo Life Sciences has revealed that two of its human proteins, which are wholly derived from human cells, are up to 53% faster in generating vital white blood cells used in the treatment of chemotherapy patients. This means cancer patients who normally have to wait for up to three weeks for white blood cell levels to regenerate before embarking on subsequent courses of chemotherapy can access potentially life saving treatments earlier. In the future, it is anticipated that patients will benefit from quicker recovery times from chemotherapy, as well as avoiding a host of side effects involved in their treatment.
Investigators Discover Modified Growth Control in Human Embryonic Stem Cells
Source: University of Massachusetts Medical School, Worcester
Date: November 17, 2006
Summary:
Two papers published by University of Massachusetts Medical School (UMMS) Department of Cell Biology and Cancer Center investigators report striking changes in control of growth in human embryonic stem cells. The studies were carried out on a National Institutes of Health funded grant using two of the six federal government approved human embryonic stem cell lines.
The implications of this work are significant. There is a pressing need to enhance capabilities for tissue regeneration, particularly for the treatment of age-related skeletal degenerative diseases that include osteoporosis and osteoarthritis, that can be met by stem cells. Utilizing human embryonic stem cells to reverse the catastrophic complications associated with diabetes, renal failure, multiple sclerosis, muscular dystrophy and Alzheimer’s with stem cells is a realistic expectation.
Date: November 17, 2006
Summary:
Two papers published by University of Massachusetts Medical School (UMMS) Department of Cell Biology and Cancer Center investigators report striking changes in control of growth in human embryonic stem cells. The studies were carried out on a National Institutes of Health funded grant using two of the six federal government approved human embryonic stem cell lines.
The implications of this work are significant. There is a pressing need to enhance capabilities for tissue regeneration, particularly for the treatment of age-related skeletal degenerative diseases that include osteoporosis and osteoarthritis, that can be met by stem cells. Utilizing human embryonic stem cells to reverse the catastrophic complications associated with diabetes, renal failure, multiple sclerosis, muscular dystrophy and Alzheimer’s with stem cells is a realistic expectation.
Penn Prof. Makes 'Hair'-Raising Stem Cell Discovery
Source: Evening Bulletin - Philadelphia, PA
Posted: November 17, 2006
Summary:
A pathology researcher at the University of Pennsylvania discovered a new type of adult stem cell that can be obtained from human hair follicles. The hair spheres can be harvested and so far differentiated into six different cells, including neurons, adipose, and muscle tissue, among others. The finding could have a broad clinical application for treating Alzheimer's disease and muscular dystrophy.
Posted: November 17, 2006
Summary:
A pathology researcher at the University of Pennsylvania discovered a new type of adult stem cell that can be obtained from human hair follicles. The hair spheres can be harvested and so far differentiated into six different cells, including neurons, adipose, and muscle tissue, among others. The finding could have a broad clinical application for treating Alzheimer's disease and muscular dystrophy.
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