Source: University of California - Berkeley
Date: June 6, 2012
Summary:
BERKELEY — One of the top suspects behind killer vascular diseases is the victim of mistaken identity, according to researchers from the University of California, Berkeley, who used genetic tracing to help hunt down the real culprit. The UC Berkeley researchers say that these newly discovered stem cells contribute to artery-hardening vascular diseases that can lead to heart attacks and strokes.
The guilty party is not the smooth muscle cells within blood vessel walls, which for decades was thought to combine with cholesterol and fat that can clog arteries. Blocked vessels can eventually lead to heart attacks and strokes, which account for one in three deaths in the United States.
Instead, a previously unknown type of stem cell — a multipotent vascular stem cell — is to blame, and it should now be the focus in the search for new treatments, the scientists report in a new study appearing June 6 in the journal Nature Communications.
Showing posts with label disease modeling. Show all posts
Showing posts with label disease modeling. Show all posts
Wednesday, June 06, 2012
Thursday, April 05, 2012
New Stem Cell Line Provides Safe, Prolific Source for Disease Modeling and Transplant Studies
Source: Children’s Hospital of Philadelphia
Date: April 5, 2012
Summary:
Researchers at the Children’s Hospital of Philadelphia have generated a new type of human stem cell that can develop into numerous types of specialized cells, including functioning pancreatic beta cells that produce insulin. Called endodermal progenitor (EP) cells, the new cells show two important advantages over embryonic stem cells and induced pluripotent stem cells: they do not form tumors when transplanted into animals, and they can form functional pancreatic beta cells in the laboratory. The study is published April 6 in the journal Cell Stem Cell.
Date: April 5, 2012
Summary:
Researchers at the Children’s Hospital of Philadelphia have generated a new type of human stem cell that can develop into numerous types of specialized cells, including functioning pancreatic beta cells that produce insulin. Called endodermal progenitor (EP) cells, the new cells show two important advantages over embryonic stem cells and induced pluripotent stem cells: they do not form tumors when transplanted into animals, and they can form functional pancreatic beta cells in the laboratory. The study is published April 6 in the journal Cell Stem Cell.
Tuesday, August 23, 2011
Stem Cell Study Offers Hope for Parkinson's Patients
Source: University of Edinburgh
Date: August 23, 2011
Summary:
Scientists at the University of Edinburgh have for the first time generated stem cells from one of the most rapidly progressing forms of Parkinson's disease. The development will help research into the condition as it will enable scientists to model the disease in the laboratory to shed light on why certain nerve cells die.
The research, led by the University of Edinburgh in collaboration with UCL (University College London), then used these skin cells to generate brain nerve cells affected by the disease. The ability to generate these nerve cells will make it easier to monitor the effectiveness of potential new drugs that could slow or halt progress of the condition. The aim would be to find drugs that can prevent the death of these key cells -- known as neurons -- which break down as a result of Parkinson's. The research was published in the journal Nature Communications.
Date: August 23, 2011
Summary:
Scientists at the University of Edinburgh have for the first time generated stem cells from one of the most rapidly progressing forms of Parkinson's disease. The development will help research into the condition as it will enable scientists to model the disease in the laboratory to shed light on why certain nerve cells die.
The research, led by the University of Edinburgh in collaboration with UCL (University College London), then used these skin cells to generate brain nerve cells affected by the disease. The ability to generate these nerve cells will make it easier to monitor the effectiveness of potential new drugs that could slow or halt progress of the condition. The aim would be to find drugs that can prevent the death of these key cells -- known as neurons -- which break down as a result of Parkinson's. The research was published in the journal Nature Communications.
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