Source: United Press International
Date: October 12, 2007 at 12:12 AM EDT
Summary:
An Italian research team says stem cells may help neutralize cells that undermine chemotherapy in patients with colon cancer.
Showing posts with label stem cells. Show all posts
Showing posts with label stem cells. Show all posts
Thursday, October 11, 2007
Wednesday, August 29, 2007
Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells
Source: Johns Hopkins Medical Institutions
Date: August 29, 2007
Summary:
A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.
Date: August 29, 2007
Summary:
A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.
Tuesday, August 14, 2007
Team finds way to create cancer stem cells: MIT achievement could aid cancer research
Source: Massachusetts Institute of Technology
Date: August 14, 2007
Summary:
MIT scientists and colleagues have found a way to create in the lab large amounts of cancer stem cells, or cells that can initiate tumors. The work, reported in the August 13 issue of Cancer Cell, could be a boon to researchers who study these elusive cells. Labs could easily grow them for use in experiments.
Date: August 14, 2007
Summary:
MIT scientists and colleagues have found a way to create in the lab large amounts of cancer stem cells, or cells that can initiate tumors. The work, reported in the August 13 issue of Cancer Cell, could be a boon to researchers who study these elusive cells. Labs could easily grow them for use in experiments.
Monday, August 13, 2007
Scientists Create Breast Tumor Stem Cells
Source: HealthDay News
Date: August 13, 2007
Summary:
U.S. scientists say they've succeeded in growing breast cancer stem cells from normal tissue. Since it is suspected that these types of cells give rise to cancer's spread, isolating them could prove invaluable in the fight against the disease, experts say.
Date: August 13, 2007
Summary:
U.S. scientists say they've succeeded in growing breast cancer stem cells from normal tissue. Since it is suspected that these types of cells give rise to cancer's spread, isolating them could prove invaluable in the fight against the disease, experts say.
Newly created cancer stem cells could aid breast cancer research
Source: Whitehead Institute for Biomedical Research
Date: August 13, 2007
Summary:
In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as “queens,” possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the “worker” cells that form the bulk of the tumor. Now an independent investigator at Brigham and Women’s Hospital and an instructor at Harvard Medical School, Ince developed a recipe for a new chemically defined culture medium and managed to grow a different type of human breast cell that ordinarily dies in culture. He transformed it into a cancer cell by inserting specific genes through a standard procedure.
Date: August 13, 2007
Summary:
In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as “queens,” possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the “worker” cells that form the bulk of the tumor. Now an independent investigator at Brigham and Women’s Hospital and an instructor at Harvard Medical School, Ince developed a recipe for a new chemically defined culture medium and managed to grow a different type of human breast cell that ordinarily dies in culture. He transformed it into a cancer cell by inserting specific genes through a standard procedure.
Friday, June 15, 2007
Cancer Stem Cells Similar To Normal Stem Cells Can Thwart Anti-cancer Agents
Source: University of Pittsburgh Schools of the Health Sciences
Date: June 15, 2007
Summary:
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis.
Date: June 15, 2007
Summary:
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual metastasis.
Tuesday, June 12, 2007
Cancer cell line behaves as stem cells
Source: United Press International
Posted: June 12, 2007 1:42 PM EDT
Summary:
An international team of U.S.-led scientists has determined a breast cancer cell line established a long time ago behaves much as do cancer stem cells. The finding supports the observation that although cancer stem cells are rare, a single cancer stem cell is sufficient to initiate and maintain a malignant tumor.
Posted: June 12, 2007 1:42 PM EDT
Summary:
An international team of U.S.-led scientists has determined a breast cancer cell line established a long time ago behaves much as do cancer stem cells. The finding supports the observation that although cancer stem cells are rare, a single cancer stem cell is sufficient to initiate and maintain a malignant tumor.
Monday, June 11, 2007
Cancer stem cells can go it alone
Source: Salk Institute
Date: June 11, 2007
Summary:
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line -- established long ago -- turned out to behave a lot like cancer stem cells.
Date: June 11, 2007
Summary:
At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line -- established long ago -- turned out to behave a lot like cancer stem cells.
Tuesday, June 05, 2007
Killer gene targets cancerous cells
Source: Baltimore Examiner
Posted: Jun 5, 2007 12:00 AM EDT
Summary:
Scientists at Johns Hopkins Medicine have discovered a gene that, when working correctly, kills cancer cells. But when malfunctioning, it allows potentially lethal tumors to grow unchecked.
Posted: Jun 5, 2007 12:00 AM EDT
Summary:
Scientists at Johns Hopkins Medicine have discovered a gene that, when working correctly, kills cancer cells. But when malfunctioning, it allows potentially lethal tumors to grow unchecked.
Monday, June 04, 2007
Researchers pinpoint colon cancer stem cells
Source: Reuters
Posted: June 4, 2007 5:09PM EDT
Summary:
Reuters reports researchers at Stanford University have discovered stem cells that cause colon cancer:
"A small population of stem cells drives tumor growth in colon cancer, researchers said on Monday in a discovery that could lead to a new approach to tackle the deadly disease." The study's lead researcher believes the finding, published in the Proceedings of the National Academy of Sciences, might lead to treatments to wipe out these cells and eradicate the cancer.
Posted: June 4, 2007 5:09PM EDT
Summary:
Reuters reports researchers at Stanford University have discovered stem cells that cause colon cancer:
"A small population of stem cells drives tumor growth in colon cancer, researchers said on Monday in a discovery that could lead to a new approach to tackle the deadly disease." The study's lead researcher believes the finding, published in the Proceedings of the National Academy of Sciences, might lead to treatments to wipe out these cells and eradicate the cancer.
Stemlike Cells May Fuel Colorectal Cancer
Source: Scientific American
Date: June 4, 2007
Summary:
Scientific American reports on a discovery by stem cell researchers at Stanford University that colon tumors contain stem cells may fuel Colorectal Cancer:
"A newly discovered group of cells present in colorectal tumors may be the source of the cancer's ability to grow unchecked. Researchers found that tumor cells containing a combination of three proteins were capable of becoming tumors again when injected into mice. They speculate that the cells may be offshoots of healthy stem cells that no longer respond to the body's natural checks against aggressive, uncontrolled growth."
Date: June 4, 2007
Summary:
Scientific American reports on a discovery by stem cell researchers at Stanford University that colon tumors contain stem cells may fuel Colorectal Cancer:
"A newly discovered group of cells present in colorectal tumors may be the source of the cancer's ability to grow unchecked. Researchers found that tumor cells containing a combination of three proteins were capable of becoming tumors again when injected into mice. They speculate that the cells may be offshoots of healthy stem cells that no longer respond to the body's natural checks against aggressive, uncontrolled growth."
Stanford researchers find cancer stem cells in colorectal tumors
Source: Stanford University Medical Center
Date: June 4, 2007
Summary:
Researchers at the Stanford University School of Medicine have identified the cancer stem cells that propagate tumors in colon and rectal cancer, a discovery that could lead to improved treatment of this deadly cancer. The work was supported by the National Institutes of Health, the Virginia and D.K. Ludwig Foundation, the California Institute for Regenerative Medicine (CIRM), and the Fondazione Italiana per la Ricerca sul Cancro.
Date: June 4, 2007
Summary:
Researchers at the Stanford University School of Medicine have identified the cancer stem cells that propagate tumors in colon and rectal cancer, a discovery that could lead to improved treatment of this deadly cancer. The work was supported by the National Institutes of Health, the Virginia and D.K. Ludwig Foundation, the California Institute for Regenerative Medicine (CIRM), and the Fondazione Italiana per la Ricerca sul Cancro.
Friday, June 01, 2007
Pediatric cancer stem cell identified
Source: Children's Hospital Boston
Date: June 1, 2007
Summary:
Researchers from Children's Hospital Boston and the Dana-Farber Cancer Institute have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood. They report their findings in the June 1 issue of Genes & Development.
Date: June 1, 2007
Summary:
Researchers from Children's Hospital Boston and the Dana-Farber Cancer Institute have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood. They report their findings in the June 1 issue of Genes & Development.
Thursday, May 31, 2007
COMMON CANCER GENE SENDS DEATH ORDER TO TINY KILLER
Source: Johns Hopkins Medical Institutions
Date: May 31, 2007
Summary:
Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for—stopping the colon cancer cells. Their report will be published in the June 8 issue of Molecular Cell.
Date: May 31, 2007
Summary:
Scientists at Johns Hopkins have discovered one way the p53 gene does what it's known for—stopping the colon cancer cells. Their report will be published in the June 8 issue of Molecular Cell.
Friday, May 18, 2007
Discovery Of The Cellular Origin Of Ewing's Sarcoma
Source: Curie Institute
Date: May 18, 2007
Summary:
Inserm researchers at the Institut Curie have identified the cells that cause Ewing's sarcoma. They are cells of the mesenchyme, the connective tissue that supports other tissues. The Institut Curie is the reference center in France for Ewing's sarcoma, a bone tumor of children, adolescents, and young adults. The researchers have also succeeded "to make" the tumor cells to become virtually normal mesenchymal cells again. These results, published in Cancer Cell on 7 May 2007, open up new therapeutic possibilities for blocking the development of Ewing's sarcoma in young patients.
Date: May 18, 2007
Summary:
Inserm researchers at the Institut Curie have identified the cells that cause Ewing's sarcoma. They are cells of the mesenchyme, the connective tissue that supports other tissues. The Institut Curie is the reference center in France for Ewing's sarcoma, a bone tumor of children, adolescents, and young adults. The researchers have also succeeded "to make" the tumor cells to become virtually normal mesenchymal cells again. These results, published in Cancer Cell on 7 May 2007, open up new therapeutic possibilities for blocking the development of Ewing's sarcoma in young patients.
Wednesday, May 16, 2007
Pediatric cancer stem cell identified: understanding the origin of ERMS
Source: Cold Spring Harbor Laboratory
Date: May 16, 2007
Summary:
As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children’s Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.
Date: May 16, 2007
Summary:
As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children’s Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.
Wednesday, May 09, 2007
Scientists discover genetic 'shut down' trigger in healthy immune cells
Source: University of Pittsburgh Schools of the Health Sciences
Date: May 9, 2007
Summary:
A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. Results of a University of Pittsburgh School of Medicine study on the mechanism, called a somatic stop-codon mutation, are being reported today in the online journal PLoS ONE, published by the Public Library of Science.
Date: May 9, 2007
Summary:
A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. Results of a University of Pittsburgh School of Medicine study on the mechanism, called a somatic stop-codon mutation, are being reported today in the online journal PLoS ONE, published by the Public Library of Science.
Tuesday, May 01, 2007
Unstable Leukemia Stem Cells May Predispose Patients To Drug Resistance
Source: Journal of the National Cancer Institute
Date: May 1, 2007
Summary:
Scientists believe the rapid mutation of a gene in chronic myeloid leukemia stem cells may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute. The original news release can be foundhere .
Date: May 1, 2007
Summary:
Scientists believe the rapid mutation of a gene in chronic myeloid leukemia stem cells may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute. The original news release can be found
WHEN stem cells TURN BAD: Researchers turn their microscopes on a new target in the fight against cancer
Source: The Columbus Dispatch
Date: May 1, 2007
Summary:
Stem cells often are heralded as having infinite curative possibilities. But a growing field of research suggests that some stem cells turn bad. And when they do, they can be hard to kill. Normal stem cells divide into one identical stem cell and a second that is an organ or tissue cell, say for the blood, skin or kidney. Cancer stem cells work the same way as normal stem cells, but with a deadly twist. When a cancer stem cell divides, one becomes an identical cancer stem cell, while the other becomes a tumor cell.
Date: May 1, 2007
Summary:
Stem cells often are heralded as having infinite curative possibilities. But a growing field of research suggests that some stem cells turn bad. And when they do, they can be hard to kill. Normal stem cells divide into one identical stem cell and a second that is an organ or tissue cell, say for the blood, skin or kidney. Cancer stem cells work the same way as normal stem cells, but with a deadly twist. When a cancer stem cell divides, one becomes an identical cancer stem cell, while the other becomes a tumor cell.
Monday, April 30, 2007
Seed study might help stem cell research
Source: United Press International
Date: April 30, 2007
Summary:
German scientists have found genomic imprinting is not always essential for seed development -- a finding with implications for stem cell research.
Date: April 30, 2007
Summary:
German scientists have found genomic imprinting is not always essential for seed development -- a finding with implications for stem cell research.
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