Transplanted photoreceptor precursor cells restore visual function in mice with retinal degeneration: U-M & London team says technique has implication

Source: University of Michigan Health System
Date: November 8, 2006

Summary:

Scientists have successfully transplanted light-sensing cells called photoreceptors directly into the eyes of mice and restored their visual function. The achievement is based on a new technology in which the cells are introduced at a particular stage in their development. The team of scientists found that transplanted photoreceptor precursor cells survived and became integrated into the mouse retina--and that the technique succeeded because the cells were isolated when they had reached a certain level of maturity. The technology represents a breakthrough in transplantation-based therapies for neuro-degenerative diseases. It suggests that scientists may need to introduce changes in stem cells in order for them to become highly specialized neurons.

Commentary: Maybe this finding will provide scientists with a basis to eventually develop specialize neurons to treat eye diseases and disorders as well as other neurological disorders and conditions.