Source: KATU-TV - Portland, Oregon
Posted: December 12, 2006 at 8:59 PM PST
This feature examines the recent clinical trial developed by Stem Cells Inc. conducted at Oregon Health & Sciences University to treat Batten Disease using stem cells from aborted fetuses.
Wednesday, December 13, 2006
Forsyth scientists discover early key to regeneration
Source: Forsyth Institute
Date: December 13, 2006
Summary:
Science may be one step closer to understanding how a limb can be grown or a spinal cord can be repaired. Scientists at The Forsyth Institute have discovered that some cells have to die for regeneration to occur. This research may provide insight into mechanisms necessary for therapeutic regeneration in humans, potentially addressing tissues that are lost, damaged or non- functional as a result of genetic syndromes, birth defects, cancer, degenerative diseases, accidents, aging and organ failure. Through studies of the frog (Xenopus) tadpole, the Forsyth team examined the cellular underpinnings of regeneration.
Date: December 13, 2006
Summary:
Science may be one step closer to understanding how a limb can be grown or a spinal cord can be repaired. Scientists at The Forsyth Institute have discovered that some cells have to die for regeneration to occur. This research may provide insight into mechanisms necessary for therapeutic regeneration in humans, potentially addressing tissues that are lost, damaged or non- functional as a result of genetic syndromes, birth defects, cancer, degenerative diseases, accidents, aging and organ failure. Through studies of the frog (Xenopus) tadpole, the Forsyth team examined the cellular underpinnings of regeneration.
Tuesday, December 12, 2006
Newts which Regrow their Hearts: Max Planck scientists reveal the molecular details of regeneration in newts
Source: Max-Planck-Institute for Heart and Lung Research
Date: December 5, 2006
Summary:
When a newt loses a limb, the limb regrows. What is more, a newt can also completely repair damage to its heart. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now started to decode the cellular mechanisms in this impressive ability to regenerate and have discovered the remarkable plasticity of newt heart cells. As mammals, and therefore also humans, do not have this ability, the findings could contribute to new cell therapies for patients with damaged organs.
Date: December 5, 2006
Summary:
When a newt loses a limb, the limb regrows. What is more, a newt can also completely repair damage to its heart. Scientists at the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now started to decode the cellular mechanisms in this impressive ability to regenerate and have discovered the remarkable plasticity of newt heart cells. As mammals, and therefore also humans, do not have this ability, the findings could contribute to new cell therapies for patients with damaged organs.
Pittsburgh-based team engineers muscle, bone cell differentiation with aid of ink-jet printer
Source: Carnegie Mellon University
Date: December 10, 2006
Summary:
A Pittsburgh-based research team has created and used an innovative ink-jet system to print "bio-ink" patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells. The results could revolutionize the design of replacement body tissues. The report is the first describing a system that can pattern the formation of multiple cell types within the same vessel from a single population of adult stem cells. The new preclinical advance in the field of regenerative medicine could one day benefit millions of people whose tissues are damaged from a variety of conditions, including fatal genetic diseases like Duchenne Muscular Dystrophy (DMD), wear and tear associated with aging joints, accidental trauma, and joint deterioration due to autoimmune disorders.
Date: December 10, 2006
Summary:
A Pittsburgh-based research team has created and used an innovative ink-jet system to print "bio-ink" patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells. The results could revolutionize the design of replacement body tissues. The report is the first describing a system that can pattern the formation of multiple cell types within the same vessel from a single population of adult stem cells. The new preclinical advance in the field of regenerative medicine could one day benefit millions of people whose tissues are damaged from a variety of conditions, including fatal genetic diseases like Duchenne Muscular Dystrophy (DMD), wear and tear associated with aging joints, accidental trauma, and joint deterioration due to autoimmune disorders.
Aggressive Stem Cells Might Improve Transplant Outcome
Source: St. Jude Children's Research Hospital
Date: December 8, 2006
Summary:
Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time. The finding is important because children whose own bone marrow stem cells have been destroyed by chemotherapy or radiation treatments for cancer routinely undergo bone marrow transplantation. Therefore, reducing the time it takes for the immune system to regenerate T lymphocytes would be an important step in reducing infection risk in these children and improving their long-term outcomes.
Date: December 8, 2006
Summary:
Investigators at St. Jude Children's Research Hospital have demonstrated in mice a way that might reduce the time it takes for a bone marrow transplant to rebuild a child's immune system, and so reduce the risk of potentially fatal virus infections that can occur during this time. The finding is important because children whose own bone marrow stem cells have been destroyed by chemotherapy or radiation treatments for cancer routinely undergo bone marrow transplantation. Therefore, reducing the time it takes for the immune system to regenerate T lymphocytes would be an important step in reducing infection risk in these children and improving their long-term outcomes.
Stem Cell Advances Offer Hope to Back Up the Hype
Source: National Geographic
Date: December 4, 2006
Summary:
Human stem cell treatments for diseases may in some cases be at least a decade away. But each new discovery has added to the notion that stem cell research is showing increasing signs of living up to the hype surrounding it.
Date: December 4, 2006
Summary:
Human stem cell treatments for diseases may in some cases be at least a decade away. But each new discovery has added to the notion that stem cell research is showing increasing signs of living up to the hype surrounding it.
Monday, December 11, 2006
Another Boost For Stem Cell Research
Source: University of New South Wales
Date: December 11, 2006
Summary:
University of New South Wales (UNSW) academics have proven that tumours can be prevented from forming when embryonic stem cells are transplanted. The team has shown that placing the embryonic cells inside microcapsules made from a product of seaweed, called alginate, prevents the formation of tumours when the encapsulated cells are transplanted into laboratory animals. The team has also shown that the encapsulation process does not stop the embryonic cells from differentiating. The finding could provide new evidence to increase support for embryonic stem cell research.
Date: December 11, 2006
Summary:
University of New South Wales (UNSW) academics have proven that tumours can be prevented from forming when embryonic stem cells are transplanted. The team has shown that placing the embryonic cells inside microcapsules made from a product of seaweed, called alginate, prevents the formation of tumours when the encapsulated cells are transplanted into laboratory animals. The team has also shown that the encapsulation process does not stop the embryonic cells from differentiating. The finding could provide new evidence to increase support for embryonic stem cell research.
Sunday, December 10, 2006
Detailed 3-D Image Catches A Key Regulator Of Neural Stem Cell Differentiation In Action
Source: Salk Institute
Date: December 10, 2006
Summary:
Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system. A finely tuned network of molecular "on" and "off" switches regulates the differentiation of embryonic stem cells into different tissue types. Being able to manipulate individual switches would allow scientists to nudge embryonic stem cells into becoming specific cell types, a plus for both basic research and potential therapies.
Date: December 10, 2006
Summary:
Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system. A finely tuned network of molecular "on" and "off" switches regulates the differentiation of embryonic stem cells into different tissue types. Being able to manipulate individual switches would allow scientists to nudge embryonic stem cells into becoming specific cell types, a plus for both basic research and potential therapies.
Friday, December 08, 2006
Diabetes cure first target for stem cell research
Source: NEWS.com.au - Australia
Posted: December 08, 2006 12:00 am
Summary:
The first big target for embryonic stem cell research in NSW will be a cure for Type 1, or juvenile diabetes, with a top researcher predicting major progress within four years. Scientists believe that once cells are studied in laboratories, they will be able to find out regulates the disease, how to can understand the disease process and how to go through drug discovery.
Posted: December 08, 2006 12:00 am
Summary:
The first big target for embryonic stem cell research in NSW will be a cure for Type 1, or juvenile diabetes, with a top researcher predicting major progress within four years. Scientists believe that once cells are studied in laboratories, they will be able to find out regulates the disease, how to can understand the disease process and how to go through drug discovery.
Brainstorming: Stem Cells Hold Hope for Cerebral Palsy Treatment
Source: Medical College of Georgia
Date: December 8, 2006
Summary:
The Medical College of Georgia reports on research using adult stem cells to treat animals with cerebral palsy:
"Adult stem cell therapy improves recovery of motor function in an animal model for the ischemic brain injury that strikes about 10 percent of babies with cerebral palsy, researchers report. Within two weeks, treated animals were about 20 percent less likely to favor the unaffected side of their bodies and experienced about a 25 percent improvement in balance, compared to untreated controls, Medical College of Georgia researchers said."
Date: December 8, 2006
Summary:
The Medical College of Georgia reports on research using adult stem cells to treat animals with cerebral palsy:
"Adult stem cell therapy improves recovery of motor function in an animal model for the ischemic brain injury that strikes about 10 percent of babies with cerebral palsy, researchers report. Within two weeks, treated animals were about 20 percent less likely to favor the unaffected side of their bodies and experienced about a 25 percent improvement in balance, compared to untreated controls, Medical College of Georgia researchers said."
A new approach to growing heart muscle: U-M team reports success of rapid 3-D cell-growth technique that produces pulsing, organized tissue
Source: University of Michigan Health System
Date: December 8, 2006
Summary:
It looks, contracts and responds almost like natural heart muscle – even though it was grown in the lab. And it brings scientists another step closer to the goal of creating replacement parts for damaged human hearts, or eventually growing an entirely new heart from just a spoonful of loose heart cells.
Date: December 8, 2006
Summary:
It looks, contracts and responds almost like natural heart muscle – even though it was grown in the lab. And it brings scientists another step closer to the goal of creating replacement parts for damaged human hearts, or eventually growing an entirely new heart from just a spoonful of loose heart cells.
Tuesday, December 05, 2006
Stem cells may provide cure for diabetes: expert
Source: Agence France-Presse (AFP)
Posted: December 5, 2006 5:52 AM ET
Summary:
Research is under way to try and covert embryonic and adult stem cells into insulin-producing pancreatic beta cells. The aim is to create a glucose-sensitive, insulin-producing cell which responds to changes in physiological glucose levels as though in a normal body.
Posted: December 5, 2006 5:52 AM ET
Summary:
Research is under way to try and covert embryonic and adult stem cells into insulin-producing pancreatic beta cells. The aim is to create a glucose-sensitive, insulin-producing cell which responds to changes in physiological glucose levels as though in a normal body.
Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
Source: Medical College of Wisconsin
Date: December 5, 2006
Summary:
Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a valuable resource for future mouse neural crest stem cell research.
Date: December 5, 2006
Summary:
Having recently identified the molecular signature of these epidermal neural crest stem cells in the mouse, their research resolves conflicting scientific opinions by showing that these cells are distinctly different from other types of skin-resident stem cells/progenitors. Their work provides a valuable resource for future mouse neural crest stem cell research.
Foetal cells 'to treat strokes'
Source: BBC News
Posted: 5 December 2006, 17:01 GMT
Summary:
ReNeuron, a UK company, is applying for permission to transplant stem cells made from human foetal tissue into the brains of stroke patients. The company claims it has convincing lab evidence that the cells could potentially regenerate brain cells damaged from a stroke.
Posted: 5 December 2006, 17:01 GMT
Summary:
ReNeuron, a UK company, is applying for permission to transplant stem cells made from human foetal tissue into the brains of stroke patients. The company claims it has convincing lab evidence that the cells could potentially regenerate brain cells damaged from a stroke.
Monday, December 04, 2006
Transplanted brain cells hold promise for Parkinson’s disease
Source: Medical College of Georgia
Date: December 4, 2006
Summary:
Transplanted neural stem cells hold promise for reducing the destruction of dopaminergic cells that occurs in Parkinson's disease and for replacing cells lost to the disease, scientists say. Research published in the current issue of The Journal of Neuroscience shows a human neural stem cell transplant essentially enables an animal with symptoms of Parkinson’s to continue functioning normally rather than displaying the progressive loss of movement control that characterizes the disease.
Date: December 4, 2006
Summary:
Transplanted neural stem cells hold promise for reducing the destruction of dopaminergic cells that occurs in Parkinson's disease and for replacing cells lost to the disease, scientists say. Research published in the current issue of The Journal of Neuroscience shows a human neural stem cell transplant essentially enables an animal with symptoms of Parkinson’s to continue functioning normally rather than displaying the progressive loss of movement control that characterizes the disease.
Transplanted brain cells hold promise for Parkinson's Disease
Source: Medical College of Georgia
Date: December 4, 2006
Summary:
Transplanted neural stem cells hold promise for reducing the destruction of dopaminergic cells that occurs in Parkinson's disease and for replacing cells lost to the disease, scientists say. Research published in the current issue of The Journal of Neuroscience shows a human neural stem cell transplant essentially enables an animal model for Parkinson’s to continue functioning normally rather than displaying the progressive loss of movement control that characterizes the disease.
Date: December 4, 2006
Summary:
Transplanted neural stem cells hold promise for reducing the destruction of dopaminergic cells that occurs in Parkinson's disease and for replacing cells lost to the disease, scientists say. Research published in the current issue of The Journal of Neuroscience shows a human neural stem cell transplant essentially enables an animal model for Parkinson’s to continue functioning normally rather than displaying the progressive loss of movement control that characterizes the disease.
Molecular 'marker' on stem cells aids research, perhaps therapies
Source: UT Southwestern Medical Center
Date: December 4, 2006
Summary:
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.
Date: December 4, 2006
Summary:
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.
Saturday, December 02, 2006
Stem cell cure for back pain 'in three years'
Source: Daily Telegraph
Date: December 1, 2006
Summary:
A researcher at the Manchester University School of Medicine has developed a new treatment chronic back pain using a patient's own stem cells, that rebuilds the soft, shock-absorbing discs that separate spinal vertebrae. The treatment has to be given only once and would not involve a hospital stay.
Date: December 1, 2006
Summary:
A researcher at the Manchester University School of Medicine has developed a new treatment chronic back pain using a patient's own stem cells, that rebuilds the soft, shock-absorbing discs that separate spinal vertebrae. The treatment has to be given only once and would not involve a hospital stay.
Friday, December 01, 2006
'Cancer Prognosis Gene' Found To Control The Fate Of Breast Cells
Source: University of California - San Francisco
Date: December 1, 2006
Summary:
Scientists have discovered an unsuspected role for a gene known to be one of the best predictors of human breast cancer outcome. The scientists hope that further investigation of the precise role of the gene in breast cancer can identify new ways of understanding, diagnosing and treating the disease.
Date: December 1, 2006
Summary:
Scientists have discovered an unsuspected role for a gene known to be one of the best predictors of human breast cancer outcome. The scientists hope that further investigation of the precise role of the gene in breast cancer can identify new ways of understanding, diagnosing and treating the disease.
Parkinson’s Approach With Stem Cells A Promising First Step
Source: University of Rochester Medical Center
Date: December 1, 2006
Summary:
Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson’s-like symptoms dramatically by transformed into neurons that produce dopamine, a crucial brain chemical lacking in patients with Parkinson’s. However, the treatment caused a significant problem – the appearance of brain tumors – that scientists are now working to solve. The study is featured on the cover of the November issue of Nature Medicine.
Date: December 1, 2006
Summary:
Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson’s-like symptoms dramatically by transformed into neurons that produce dopamine, a crucial brain chemical lacking in patients with Parkinson’s. However, the treatment caused a significant problem – the appearance of brain tumors – that scientists are now working to solve. The study is featured on the cover of the November issue of Nature Medicine.
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