Source: University of Illinois at Urbana-Champaign
Date: October 19, 2009
Summary:
CHAMPAIGN, Ill. – Applying a small mechanical force to embryonic stem cells could be a new way of coaxing them into a specific direction of differentiation, researchers at the University of Illinois report. Applications for force-directed cell differentiation include therapeutic cloning and regenerative medicine. Results suggest that small forces may indeed play critical roles in inducing strong biological responses in embryonic stem cells, and in shaping embryos during their early development. The research is published in Nature Materials.
Showing posts with label cloning. Show all posts
Showing posts with label cloning. Show all posts
Monday, October 19, 2009
Thursday, April 03, 2008
Advanced Cell Technology Platform Yields Over 140 Cell Types from Human Embryonic Stem Cells
Source: Advanced Cell Technology, Inc.
Posted: April 3, 2008 11:19 AM EDT
Summary:
Advanced Cell Technology, Inc. reports it has developed a large-scale differentiation process that has generated panels of differentiating human progenitor cell lines from human embryonic stem cells (hESCs):
"Advanced Cell Technology, Inc. reported on a large-scale differentiation process that has generated panels of differentiating human progenitor cell lines from human embryonic stem cells (hESCs). The research will be published in the April issue of Regenerative Medicine. ...One of the hurdles has been a commercially viable means for the expansion of sufficient numbers of the cell types needed for tissue regeneration. With the publication of work entitled 'The ACTCellerate Initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives,' ACT scientists have solved some of these problems. The paper describes a system that was established to isolate and clonally expand tissue specific precursors that heretofore could only be isolated from aborted human fetal tissue."
Posted: April 3, 2008 11:19 AM EDT
Summary:
Advanced Cell Technology, Inc. reports it has developed a large-scale differentiation process that has generated panels of differentiating human progenitor cell lines from human embryonic stem cells (hESCs):
"Advanced Cell Technology, Inc. reported on a large-scale differentiation process that has generated panels of differentiating human progenitor cell lines from human embryonic stem cells (hESCs). The research will be published in the April issue of Regenerative Medicine. ...One of the hurdles has been a commercially viable means for the expansion of sufficient numbers of the cell types needed for tissue regeneration. With the publication of work entitled 'The ACTCellerate Initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives,' ACT scientists have solved some of these problems. The paper describes a system that was established to isolate and clonally expand tissue specific precursors that heretofore could only be isolated from aborted human fetal tissue."
Tuesday, April 01, 2008
British team makes mixed human animal embryos
Source: The Times
Date: April 1, 2008
Summary:
The Times reports British researchers created animal embryos containing human DNA for the first time:
"Embryos containing both human and animal material have been created in Britain for the first time, a month before the House of Commons is to vote on new laws to regulate the controversial research. A team at the University of Newcastle-upon-Tyne announced tonight that it had successfully generated 'admixed embryos' by adding human DNA to empty cow eggs, in the first experiment of its kind in the UK."
Date: April 1, 2008
Summary:
The Times reports British researchers created animal embryos containing human DNA for the first time:
"Embryos containing both human and animal material have been created in Britain for the first time, a month before the House of Commons is to vote on new laws to regulate the controversial research. A team at the University of Newcastle-upon-Tyne announced tonight that it had successfully generated 'admixed embryos' by adding human DNA to empty cow eggs, in the first experiment of its kind in the UK."
Tuesday, March 25, 2008
Coverage of Parkinson's Stem Cell Study
Below is a summary of media coverage from various sources of recent studies by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) using embryonic stem cells derived from therapeutic cloning to treat Parkinson's Disease in mice:
Medical News Today, 25 March 2008 - 2:00 PDT:
"In a step closer to developing a treatment for Parkinson's in humans using therapeutic cloning, scientists in the US and Japan have for the first time used cells from a mouse to treat Parkinson's in the same mouse. The study is published in the advanced online issue of the journal Nature Medicine and is the work of investigators at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, and the Riken Institute in Kobe, Japan. Hailed as the first study of its kind, the investigators showed that therapeutic cloning, or somatic cell nuclear transfer (SNCT), using cells from a mouse to treat the same mouse can be successful. Although so far only demonstrated in animals, if the success is replicated in humans, it will open the door to treatments that reduce transplant rejection and improve recovery in a range of other diseases and medical conditions."
United Press International, March 24, 2008 at 2:57 PM EDT:
"A U.S. and Japanese study used therapeutic cloning to treat Parkinson's disease in mice. The nucleus taken from skin cells from the tail of the mouse were used to generate "customized" dopamine neurons. The study, published online in Nature Medicine, found mice receiving dopamine neurons from the individually matched stem cell lines showed neurological improvement. But when these neurons were grafted into mice that did not genetically match the transplanted cells, the cells did not survive well and the mice did not recover."
HealthDay News, March 24, 2008:
"Therapeutic cloning successfully treated Parkinson's disease in mice, researchers report. Using the process to develop dopamine-producing neurons with an identical genetic profile to each mouse being treated allowed scientists to significantly improve the neurological performance of the diseased animals, without provoking any evidence of immune system rejection."
ScienceNOW Daily News, 24 March 2008:
"Scientists have moved a step closer toward therapeutic cloning, the strategy of using patients' own cells to treat their diseases. Mice with a Parkinson-like movement disorder showed significant improvement after being implanted with brain cells derived from their own tissue. It's a "technical tour de force," says Harvard stem cell researcher George Daley."
The Independent, 24 March 2008:
"A potential cure for Parkinson's disease has come a significant step closer today with a study showing that it is possible to treat the degenerative brain disorder with cells derived from cloned embryos – a development condemned by the Roman Catholic Church. The research was carried out on laboratory mice but scientists believe the findings are proof that the techniques could be applied to humans suffering not just from Parkinson's, but a range of other incurable diseases. Researchers have demonstrated the possibility of treating Parkinson's disease by transplanting laboratory-matured brain cells back into the individual who supplied the skin cells that were turned into cloned embryos – a process known as therapeutic cloning."
Daily Mail - Glasgow, UK, 24th March 2008, 11:07am GMT:
"A potential cure for Parkinson's disease has come a significant step closer today with a study showing that it is possible to treat the degenerative brain disorder with cells derived from cloned embryos. The cells were successfully used to treat animals with the disease for the first time. The experiment marked the first time that cloned stem cells had been used to reverse disease in the same animals from which they were taken. Mice bred to develop the equivalent of Parkinson's showed signs of improvement when they received neurons containing the chemical dopamine which had been grown from their own cloned stem cells. The findings, published in the journal Nature Medicine, suggest it could be possible to use this cloning approach, known as therapeutic cloning, to treat Parkinson's in humans."
Sydney Morning Herald, March 24, 2008 - 6:33 AM
AST:
"THE controversial technique of therapeutic cloning has been successfully used to treat a disease for the first time, with mice with Parkinson's disease found to improve after receiving their own modified cells. American and Japanese researchers converted skin cells from the tail of the sick animals into the dopamine-producing brain cells they lacked, and grafted the genetically matched tissue back into the same mice."
BBC News 23 March 2008 19:03 GMT:
"Therapeutic cloning has been successfully used to treat Parkinson's disease in mice, US researchers say. The study in Nature Medicine provides the best evidence so far that the controversial technique could one day help people with the condition. The Memorial Sloan-Kettering Cancer Centre team say it is the first time animals have been successfully treated with their own cloned cells. UK experts said the work was promising and exciting development."
Bloomberg News, March 23, 2008:
"Researchers cured mice with a version of Parkinson's disease by treating them with brain cells made from clones of their own skin cells. The researchers employed nuclear transfer, which involves swapping genetic material from one individual into an egg cell belonging to another. The same procedure was used to create Dolly the sheep, one of the first animals produced by cloning. The findings, published today in the journal Nature Medicine, offer a glimpse into how the cloning technique might one day be used to develop therapies, as opposed to making copies of an individual."
Bloomberg News, March 23, 2008:
"Researchers cured mice with a version of Parkinson's disease by treating them with brain cells made from clones of their own skin cells. The researchers employed nuclear transfer, which involves swapping genetic material from one individual into an egg cell belonging to another. The same procedure was used to create Dolly the sheep, one of the first animals produced by cloning. The findings, published today in the journal Nature Medicine, offer a glimpse into how the cloning technique might one day be used to develop therapies, as opposed to making copies of an individual."
The Guardian, March 24, 2008:
"Scientists have shown that stem cells produced by therapeutic cloning are effective for treating Parkinson's disease, in the first convincing demonstration that stem cells derived from the subject can be used to treat a serious disease. The technique has only been tried in mice, but scientists have hailed it as proof that a similar approach could be successful in humans."
The Times, March 24, 2008:
"Cloned embryonic stem cells have been used to treat animals with Parkinson’s disease for the first time, in an important step towards developing the therapy for human patients. The successful experiment marks the first time that cloned stem cells have been used to reverse disease in the same animals from which they were derived, and suggests that it should be possible to use therapeutic cloning in medicine."
Reuters, March 23, 2008 2:05 pm EDT:
"Researchers who used cloned embryonic stem cells to treat Parkinson's disease in mice said on Sunday they worked better than other cells. The researchers were trying to prove that it is possible to make embryonic stem cells using cloning technology and use them to provide a tailor-made treatment. But they found that a mouse's own cloned stem cells were far less disruptive to its body than cloned cells taken from other mice."
New Scientist, 18:00 GMT 23 March 2008:
"Therapeutic cloning works – in mice, at least. An international team has restored mice with a condition similar to Parkinson's disease back to health, using neurons grown in the lab that were made from their own cloned skin cells. This is the first time that a disease has been successfully treated using cloned cells that had been derived from the recipient animals."
The Courier Mail, March 24, 2008 05:30am AST:
"RESEARCHERS who used cloned embryonic stem cells to treat Parkinson's disease in mice said today they worked better than other cells. The researchers were trying to prove that it is possible to make embryonic stem cells using cloning technology and use them to provide a tailor-made treatment. But they found that a mouse's own cloned stem cells were far less disruptive to its body than cloned cells taken from other mice."
Medical News Today, 25 March 2008 - 2:00 PDT:
"In a step closer to developing a treatment for Parkinson's in humans using therapeutic cloning, scientists in the US and Japan have for the first time used cells from a mouse to treat Parkinson's in the same mouse. The study is published in the advanced online issue of the journal Nature Medicine and is the work of investigators at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York, and the Riken Institute in Kobe, Japan. Hailed as the first study of its kind, the investigators showed that therapeutic cloning, or somatic cell nuclear transfer (SNCT), using cells from a mouse to treat the same mouse can be successful. Although so far only demonstrated in animals, if the success is replicated in humans, it will open the door to treatments that reduce transplant rejection and improve recovery in a range of other diseases and medical conditions."
United Press International, March 24, 2008 at 2:57 PM EDT:
"A U.S. and Japanese study used therapeutic cloning to treat Parkinson's disease in mice. The nucleus taken from skin cells from the tail of the mouse were used to generate "customized" dopamine neurons. The study, published online in Nature Medicine, found mice receiving dopamine neurons from the individually matched stem cell lines showed neurological improvement. But when these neurons were grafted into mice that did not genetically match the transplanted cells, the cells did not survive well and the mice did not recover."
HealthDay News, March 24, 2008:
"Therapeutic cloning successfully treated Parkinson's disease in mice, researchers report. Using the process to develop dopamine-producing neurons with an identical genetic profile to each mouse being treated allowed scientists to significantly improve the neurological performance of the diseased animals, without provoking any evidence of immune system rejection."
ScienceNOW Daily News, 24 March 2008:
"Scientists have moved a step closer toward therapeutic cloning, the strategy of using patients' own cells to treat their diseases. Mice with a Parkinson-like movement disorder showed significant improvement after being implanted with brain cells derived from their own tissue. It's a "technical tour de force," says Harvard stem cell researcher George Daley."
The Independent, 24 March 2008:
"A potential cure for Parkinson's disease has come a significant step closer today with a study showing that it is possible to treat the degenerative brain disorder with cells derived from cloned embryos – a development condemned by the Roman Catholic Church. The research was carried out on laboratory mice but scientists believe the findings are proof that the techniques could be applied to humans suffering not just from Parkinson's, but a range of other incurable diseases. Researchers have demonstrated the possibility of treating Parkinson's disease by transplanting laboratory-matured brain cells back into the individual who supplied the skin cells that were turned into cloned embryos – a process known as therapeutic cloning."
Daily Mail - Glasgow, UK, 24th March 2008, 11:07am GMT:
"A potential cure for Parkinson's disease has come a significant step closer today with a study showing that it is possible to treat the degenerative brain disorder with cells derived from cloned embryos. The cells were successfully used to treat animals with the disease for the first time. The experiment marked the first time that cloned stem cells had been used to reverse disease in the same animals from which they were taken. Mice bred to develop the equivalent of Parkinson's showed signs of improvement when they received neurons containing the chemical dopamine which had been grown from their own cloned stem cells. The findings, published in the journal Nature Medicine, suggest it could be possible to use this cloning approach, known as therapeutic cloning, to treat Parkinson's in humans."
Sydney Morning Herald, March 24, 2008 - 6:33 AM
AST:
"THE controversial technique of therapeutic cloning has been successfully used to treat a disease for the first time, with mice with Parkinson's disease found to improve after receiving their own modified cells. American and Japanese researchers converted skin cells from the tail of the sick animals into the dopamine-producing brain cells they lacked, and grafted the genetically matched tissue back into the same mice."
BBC News 23 March 2008 19:03 GMT:
"Therapeutic cloning has been successfully used to treat Parkinson's disease in mice, US researchers say. The study in Nature Medicine provides the best evidence so far that the controversial technique could one day help people with the condition. The Memorial Sloan-Kettering Cancer Centre team say it is the first time animals have been successfully treated with their own cloned cells. UK experts said the work was promising and exciting development."
Bloomberg News, March 23, 2008:
"Researchers cured mice with a version of Parkinson's disease by treating them with brain cells made from clones of their own skin cells. The researchers employed nuclear transfer, which involves swapping genetic material from one individual into an egg cell belonging to another. The same procedure was used to create Dolly the sheep, one of the first animals produced by cloning. The findings, published today in the journal Nature Medicine, offer a glimpse into how the cloning technique might one day be used to develop therapies, as opposed to making copies of an individual."
Bloomberg News, March 23, 2008:
"Researchers cured mice with a version of Parkinson's disease by treating them with brain cells made from clones of their own skin cells. The researchers employed nuclear transfer, which involves swapping genetic material from one individual into an egg cell belonging to another. The same procedure was used to create Dolly the sheep, one of the first animals produced by cloning. The findings, published today in the journal Nature Medicine, offer a glimpse into how the cloning technique might one day be used to develop therapies, as opposed to making copies of an individual."
The Guardian, March 24, 2008:
"Scientists have shown that stem cells produced by therapeutic cloning are effective for treating Parkinson's disease, in the first convincing demonstration that stem cells derived from the subject can be used to treat a serious disease. The technique has only been tried in mice, but scientists have hailed it as proof that a similar approach could be successful in humans."
The Times, March 24, 2008:
"Cloned embryonic stem cells have been used to treat animals with Parkinson’s disease for the first time, in an important step towards developing the therapy for human patients. The successful experiment marks the first time that cloned stem cells have been used to reverse disease in the same animals from which they were derived, and suggests that it should be possible to use therapeutic cloning in medicine."
Reuters, March 23, 2008 2:05 pm EDT:
"Researchers who used cloned embryonic stem cells to treat Parkinson's disease in mice said on Sunday they worked better than other cells. The researchers were trying to prove that it is possible to make embryonic stem cells using cloning technology and use them to provide a tailor-made treatment. But they found that a mouse's own cloned stem cells were far less disruptive to its body than cloned cells taken from other mice."
New Scientist, 18:00 GMT 23 March 2008:
"Therapeutic cloning works – in mice, at least. An international team has restored mice with a condition similar to Parkinson's disease back to health, using neurons grown in the lab that were made from their own cloned skin cells. This is the first time that a disease has been successfully treated using cloned cells that had been derived from the recipient animals."
The Courier Mail, March 24, 2008 05:30am AST:
"RESEARCHERS who used cloned embryonic stem cells to treat Parkinson's disease in mice said today they worked better than other cells. The researchers were trying to prove that it is possible to make embryonic stem cells using cloning technology and use them to provide a tailor-made treatment. But they found that a mouse's own cloned stem cells were far less disruptive to its body than cloned cells taken from other mice."
Sunday, March 23, 2008
Therapeutic Cloning Treats Parkinson's Disease in Mice
Source: Memorial Sloan-Kettering Cancer Center
Date: March 23, 2008
Summary:
Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice. The study's results are published in the March 23 online edition of the journal Nature Medicine. For the first time, researchers showed that therapeutic cloning or SCNT has been successfully used to treat disease in the same subjects from whom the initial cells were derived. While this current work is in animals, it could have future implications as this method may be an effective way to reduce transplant rejection and enhance recovery in other diseases and in other organ systems.
Date: March 23, 2008
Summary:
Research led by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice. The study's results are published in the March 23 online edition of the journal Nature Medicine. For the first time, researchers showed that therapeutic cloning or SCNT has been successfully used to treat disease in the same subjects from whom the initial cells were derived. While this current work is in animals, it could have future implications as this method may be an effective way to reduce transplant rejection and enhance recovery in other diseases and in other organ systems.
Friday, March 21, 2008
Therapeutic cloning creates perfect match: Animal-specific stem cells treat Parkinson's symptoms in mice.
Source: Nature
Date: 21 March 2008
Summary:
Nature reports researchers have treated Parkinson's disease in mice using embryonic stem cells derived from therapeutic cloning:
"Researchers have used therapeutic cloning to transform a mouse's tail cells into ones that can treat it for disease. The study helps advance the prospect of creating cell lines perfectly matched to human patients. ... "The process is laborious and technically challenging. Previous work had shown that dopamine-producing cells formed from embryonic stem cells could be transplanted into mice with a model of Parkinson’s disease. The transplants successfully relieved symptoms, but in that case the researchers derived the stem cell line from a different (but genetically related) donor, not from the mouse that was being treated. The new study is the first to take cells from a mouse, transform them through therapeutic cloning into a new cell line, and use this to treat the original donor."
Date: 21 March 2008
Summary:
Nature reports researchers have treated Parkinson's disease in mice using embryonic stem cells derived from therapeutic cloning:
"Researchers have used therapeutic cloning to transform a mouse's tail cells into ones that can treat it for disease. The study helps advance the prospect of creating cell lines perfectly matched to human patients. ... "The process is laborious and technically challenging. Previous work had shown that dopamine-producing cells formed from embryonic stem cells could be transplanted into mice with a model of Parkinson’s disease. The transplants successfully relieved symptoms, but in that case the researchers derived the stem cell line from a different (but genetically related) donor, not from the mouse that was being treated. The new study is the first to take cells from a mouse, transform them through therapeutic cloning into a new cell line, and use this to treat the original donor."
Friday, January 18, 2008
Embryos are cloned using skin cells DNA and egg together reached a stage that could produce stem cells.
Source: Bloomberg News
Date: January 18, 2008
Summary:
Bloomberg News reports researchers successfully cloned human embryos using DNA from adult skin cells:
"Five human embryos were cloned using donated DNA from skin cells, a technique that may lead to treatments based on patients' own stem cells. Researchers said the DNA came from the skin of two men, while three women donated eggs. The research, led by Andrew French, the chief science officer of the closely held biotechnology company Stemagen Corp., is detailed in a report published today by the journal Stem Cells."
Date: January 18, 2008
Summary:
Bloomberg News reports researchers successfully cloned human embryos using DNA from adult skin cells:
"Five human embryos were cloned using donated DNA from skin cells, a technique that may lead to treatments based on patients' own stem cells. Researchers said the DNA came from the skin of two men, while three women donated eggs. The research, led by Andrew French, the chief science officer of the closely held biotechnology company Stemagen Corp., is detailed in a report published today by the journal Stem Cells."
Thursday, January 17, 2008
TV News Coverage of Stemagen Human Embryo Cloning Announcement
Below are links to videos of TV news coverage of the announcement by biotechnology company Stemagen, Inc. that it cloned a human embryo using somatic cell nuclear transfer (SCNT):
"SoCal Lab Says It Cloned Human Embryos: Stemagen Says Technology Will Be Used To Create Stem Cells"
Source: NBC 11 Bay Area San Jose, CA
POSTED: 11:44 am PST January 17, 2008
UPDATED: 12:03 pm PST January 17, 2008
"Local Company Successfully Clones Human Embryos"
Source: 10News San Diego, CA
POSTED: 8:02 am PST January 17, 2008
UPDATED: 12:04 pm PST January 17, 2008
"SoCal Lab Says It Cloned Human Embryos: Stemagen Says Technology Will Be Used To Create Stem Cells"
Source: NBC 11 Bay Area San Jose, CA
POSTED: 11:44 am PST January 17, 2008
UPDATED: 12:03 pm PST January 17, 2008
"Local Company Successfully Clones Human Embryos"
Source: 10News San Diego, CA
POSTED: 8:02 am PST January 17, 2008
UPDATED: 12:04 pm PST January 17, 2008
Stemagen First to Create Cloned Human Embryos From Adult Cells
Source: Stemagen Inc.
Posted: January 17, 2008 9:01 am ET
Summary:
Stemagen, a privately held embryonic stem cell research company, announced today it has become the first in the world to create, and meticulously document, a cloned human embryo using somatic cell nuclear transfer (SCNT). Stemagen CEO Samuel H. Wood, M.D., Ph.D., a co-author of the publication and a donor of the cells from which the embryos were cloned, terms this achievement "a critical milestone in the development of patient-specific embryonic stem cells for human therapeutic use, potentially including developing treatments for Parkinson's, Alzheimer's and other degenerative diseases." Stemagen's research is exhaustively detailed in a paper published in today's issue of the highly regarded peer-reviewed scientific journal Stem Cells.
Posted: January 17, 2008 9:01 am ET
Summary:
Stemagen, a privately held embryonic stem cell research company, announced today it has become the first in the world to create, and meticulously document, a cloned human embryo using somatic cell nuclear transfer (SCNT). Stemagen CEO Samuel H. Wood, M.D., Ph.D., a co-author of the publication and a donor of the cells from which the embryos were cloned, terms this achievement "a critical milestone in the development of patient-specific embryonic stem cells for human therapeutic use, potentially including developing treatments for Parkinson's, Alzheimer's and other degenerative diseases." Stemagen's research is exhaustively detailed in a paper published in today's issue of the highly regarded peer-reviewed scientific journal Stem Cells.
Thursday, December 20, 2007
New stem cell therapy said to be universal
Source: San Diego Union-Tribune
Date: December 20, 2007
Summary:
The San Diego Union-Tribune reports International Stem Cell Corporation has created embryonic stem cell lines that are a genetic match to patients, potentially eliminating risks of immune system rejection:
"In a step toward one-size-fits-all stem cell therapies, an Oceanside biotechnology company said yesterday that it has developed cell lines that could potentially be used by many different people and races without fear of transplant rejection. Scientists at International Stem Cell Corp. said the four embryonic stem cell lines have a simple genetic profile in critical areas of DNA that code for immune system rejection, making them easy to “immune match” with large numbers of patients."
Date: December 20, 2007
Summary:
The San Diego Union-Tribune reports International Stem Cell Corporation has created embryonic stem cell lines that are a genetic match to patients, potentially eliminating risks of immune system rejection:
"In a step toward one-size-fits-all stem cell therapies, an Oceanside biotechnology company said yesterday that it has developed cell lines that could potentially be used by many different people and races without fear of transplant rejection. Scientists at International Stem Cell Corp. said the four embryonic stem cell lines have a simple genetic profile in critical areas of DNA that code for immune system rejection, making them easy to “immune match” with large numbers of patients."
Human embryonic stem cell lines created that avoid immune rejection
Source: Mary Ann Liebert, Inc.
Date: December 20, 2007
Summary:
In a groundbreaking experiment published in Cloning & Stem Cells, scientists from International Stem Cell Corporation derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are “HLA-homozygous,” meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection. The lines could serve to create a stem cell bank as a renewable source of transplantable cells for use in cell therapy to replace damaged tissues or to treat genetic and degenerative diseases.
Date: December 20, 2007
Summary:
In a groundbreaking experiment published in Cloning & Stem Cells, scientists from International Stem Cell Corporation derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are “HLA-homozygous,” meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection. The lines could serve to create a stem cell bank as a renewable source of transplantable cells for use in cell therapy to replace damaged tissues or to treat genetic and degenerative diseases.
Wednesday, December 19, 2007
International Stem Cell Corporation Creates Human Stem Cell Lines That Can Eliminate Immune Rejection by Patients
Source: International Stem Cell Corporation
Posted: December 19, 2007 12:01 PM EST
Summary:
In an official company news release, International Stem Cell Corporation, a biotechnology company in the field of stem cell research, announced it has successfully created human stem cell lines that match human beings, eliminating the risk of immune rejection in patients:
"Scientists at International Stem Cell Corporation have created unique human stem cell lines that make them easily “immune matched” to human beings and could enable the creation of a bank of stem cells that could be used, without rejection, by a majority of the different people and races of the world."
The release also explains the significance of this finding:
"Akin to the concept of finding multiple 'universal Type O blood donors', the discovery is significant because it would eliminate the need for harsh immune suppression drugs currently used for cell transplant therapy. This may open the door to cell transplant therapy for diseases such as juvenile diabetes where the use of immune suppressant drugs is harmful to the patient."
Posted: December 19, 2007 12:01 PM EST
Summary:
In an official company news release, International Stem Cell Corporation, a biotechnology company in the field of stem cell research, announced it has successfully created human stem cell lines that match human beings, eliminating the risk of immune rejection in patients:
"Scientists at International Stem Cell Corporation have created unique human stem cell lines that make them easily “immune matched” to human beings and could enable the creation of a bank of stem cells that could be used, without rejection, by a majority of the different people and races of the world."
The release also explains the significance of this finding:
"Akin to the concept of finding multiple 'universal Type O blood donors', the discovery is significant because it would eliminate the need for harsh immune suppression drugs currently used for cell transplant therapy. This may open the door to cell transplant therapy for diseases such as juvenile diabetes where the use of immune suppressant drugs is harmful to the patient."
Friday, November 16, 2007
First Primate Embryonic Stem Cells Cloned By US Scientists
Source: Medical News Today
Article Date: 16 November 2007 - 6:00 PST
Summary:
US scientists have successfully created cloned primate embryos for the first time and used them to make embryonic stem cells. Their work is published in the early online issue of the journal Nature. Researchers at the Oregon National Primate Research Center (ONPRC) based at Oregon Health & Science University (OHSU) in Portland, Oregon, in collaboration with a number of other biomedical research organizations, have successfully produced monkey embryonic stem cells by using a new method to remove the nucleus of the eggs being used.
Article Date: 16 November 2007 - 6:00 PST
Summary:
US scientists have successfully created cloned primate embryos for the first time and used them to make embryonic stem cells. Their work is published in the early online issue of the journal Nature. Researchers at the Oregon National Primate Research Center (ONPRC) based at Oregon Health & Science University (OHSU) in Portland, Oregon, in collaboration with a number of other biomedical research organizations, have successfully produced monkey embryonic stem cells by using a new method to remove the nucleus of the eggs being used.
Thursday, November 15, 2007
Scientists Reach Breakthrough in Cloning Monkey Embryos
Source: The Online NewsHour
Date: November 15, 2007
Summary:
In a streaming media online broadcast, NewsHour reports scientists say they have extracted embryonic stem cells from cloned monkey embryos. It's the first time that method has been successful with primates.
Date: November 15, 2007
Summary:
In a streaming media online broadcast, NewsHour reports scientists say they have extracted embryonic stem cells from cloned monkey embryos. It's the first time that method has been successful with primates.
Clones of monkey embryos raise hopes for stem cell research
Source: San Francisco Chronicle
Date: November 15, 2007
Summary:
Researchers revealed that they have successfully cloned embryos of rhesus monkeys and obtained stem cells from them that could be turned into heart and nerve tissue - a laboratory breakthrough that could one day lead to similar work in human beings. The study renews the belief, previously dashed by fraud, that a similar process using cloned human embryos could create transplant tissue genetically matched to patients, thus avoiding the risk of rejection.
Date: November 15, 2007
Summary:
Researchers revealed that they have successfully cloned embryos of rhesus monkeys and obtained stem cells from them that could be turned into heart and nerve tissue - a laboratory breakthrough that could one day lead to similar work in human beings. The study renews the belief, previously dashed by fraud, that a similar process using cloned human embryos could create transplant tissue genetically matched to patients, thus avoiding the risk of rejection.
Scientists Use Monkey Clones to Extract Stem Cells
Source: New York Times
Date: November 15, 2007
Summary:
The New York Times reports researchers have obtained stem cells from cloned monkey embryos:
"Researchers in Oregon are reporting that they used cloning to produce monkey embryos and then extracted stem cells from the embryos."
The story mentions this new discovery could eventually be applied to treat human medical conditions:
"Not only is this the first time such cells have been produced in any animal other than a mouse, but the method, the researchers say, should also work in humans. In 2004, South Korean researchers reported making stem cells from cloned human embryos, but the claim turned out fraudulent."
The study's lead author believes this new cloning technique could also be used to produce human embryonic stem cells:
'We hope the technology will be useful for other labs that are working on human eggs and human cells,” the lead researcher of the group, Shoukhrat Mitalipov at Oregon Health and Science University in Beaverton, said in a telephone interview. “I am quite sure it will work in humans.'”
Date: November 15, 2007
Summary:
The New York Times reports researchers have obtained stem cells from cloned monkey embryos:
"Researchers in Oregon are reporting that they used cloning to produce monkey embryos and then extracted stem cells from the embryos."
The story mentions this new discovery could eventually be applied to treat human medical conditions:
"Not only is this the first time such cells have been produced in any animal other than a mouse, but the method, the researchers say, should also work in humans. In 2004, South Korean researchers reported making stem cells from cloned human embryos, but the claim turned out fraudulent."
The study's lead author believes this new cloning technique could also be used to produce human embryonic stem cells:
'We hope the technology will be useful for other labs that are working on human eggs and human cells,” the lead researcher of the group, Shoukhrat Mitalipov at Oregon Health and Science University in Beaverton, said in a telephone interview. “I am quite sure it will work in humans.'”
Wednesday, November 14, 2007
Monkey embryos cloned in stem cell first
Source: Financial Times
Published: November 15 2007 04:31 | Last updated: November 15 2007 04:31
Summary:
The Financial Times reports researchers derived stem cells from cloned monkey embryos:
"Scientists in the US have for the first time made cloned embryos from adult monkeys and extracted stem cells from them. The success, published online by the journal Nature, will encourage researchers who want to create cloned human embryos for stem cell experiments."
Published: November 15 2007 04:31 | Last updated: November 15 2007 04:31
Summary:
The Financial Times reports researchers derived stem cells from cloned monkey embryos:
"Scientists in the US have for the first time made cloned embryos from adult monkeys and extracted stem cells from them. The success, published online by the journal Nature, will encourage researchers who want to create cloned human embryos for stem cell experiments."
Stem-Cell Researchers Clone Monkey Embryo
Source: NPR
Date: November 14, 2007
Summary:
In a streaming radio broadcast, National Public Radio (NPR) reports scientists have cloned a money embryo:
" Scientists have announced another first in cloning: They have cloned a primate embryo. The researchers in Oregon say they used those cloned monkey embryos to derive embryonic stem cells. Researchers hope to one day use such a process in humans to create customized stem-cell therapies for individual patients."
Date: November 14, 2007
Summary:
In a streaming radio broadcast, National Public Radio (NPR) reports scientists have cloned a money embryo:
" Scientists have announced another first in cloning: They have cloned a primate embryo. The researchers in Oregon say they used those cloned monkey embryos to derive embryonic stem cells. Researchers hope to one day use such a process in humans to create customized stem-cell therapies for individual patients."
Researchers clone monkeys for stem cells
Source: Reuters
Posted: November 14, 2007 1:02pm ET
Summary:
Reuters reports researchers have derived stem cells from cloned monkey embryos:
"U.S. researchers have cloned monkeys and used the resulting embryos to get valued embryonic stem cells, an important step towards being able to do the same thing in humans, they reported on Wednesday. Shoukhrat Mitalipov and colleagues at Oregon Health & Science University said they used skin cells from monkeys to create cloned embryos, and then extracted embryonic stem cells from these days-old embryos."
Posted: November 14, 2007 1:02pm ET
Summary:
Reuters reports researchers have derived stem cells from cloned monkey embryos:
"U.S. researchers have cloned monkeys and used the resulting embryos to get valued embryonic stem cells, an important step towards being able to do the same thing in humans, they reported on Wednesday. Shoukhrat Mitalipov and colleagues at Oregon Health & Science University said they used skin cells from monkeys to create cloned embryos, and then extracted embryonic stem cells from these days-old embryos."
OHSU Scientists First To Successfully Create Primate Embryonic Stem Cells
Source: Oregon Health & Science University
Date: November 14, 2007
Summary:
Researchers at Oregon Health & Science University’s Oregon National Primate Research Center have made a significant breakthrough in efforts to develop human stem cell therapies that may be used to combat numerous devastating diseases. For the first time, scientists have successfully derived embryonic stem cells by reprogramming of genetic material from skin cells while studying rhesus macaque monkeys. The breakthrough follows several previously unsuccessful attempts by the OHSU-based team and other scientific teams worldwide. The results of the work were released online today by the scientific journal Nature. The work will also be published in next week’s edition of the journal.
Date: November 14, 2007
Summary:
Researchers at Oregon Health & Science University’s Oregon National Primate Research Center have made a significant breakthrough in efforts to develop human stem cell therapies that may be used to combat numerous devastating diseases. For the first time, scientists have successfully derived embryonic stem cells by reprogramming of genetic material from skin cells while studying rhesus macaque monkeys. The breakthrough follows several previously unsuccessful attempts by the OHSU-based team and other scientific teams worldwide. The results of the work were released online today by the scientific journal Nature. The work will also be published in next week’s edition of the journal.
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