Source: University of California, Los Angeles (UCLA), Health Sciences
Date: June 12, 2012
Summary:
UCLA stem cell scientists who purified a subset of stem cells from fat tissue and used the stem cells to grow bone discovered that the bone formed faster and was of higher quality than bone grown using traditional methods. The finding may one day eliminate the need for painful bone grafts that use material taken from patients during invasive procedures. The study was published June 11 in the early online edition of Stem Cells Translational Medicine.
Showing posts with label fat. Show all posts
Showing posts with label fat. Show all posts
Tuesday, June 12, 2012
Thursday, September 01, 2011
Scientists Find Stem Cells That Tell Hair It’s Time to Grow
Source: Yale University
Date: September 1, 2011
Summary:
New Haven, Conn. — Yale researchers have discovered the source of signals that trigger hair growth, an insight that may lead to new treatments for baldness. The researchers identified stem cells within the skin's fatty layer and showed that molecular signals from these cells were necessary to spur hair growth in mice, according to research published in the Sept. 2 issue of the journal Cell.
Date: September 1, 2011
Summary:
New Haven, Conn. — Yale researchers have discovered the source of signals that trigger hair growth, an insight that may lead to new treatments for baldness. The researchers identified stem cells within the skin's fatty layer and showed that molecular signals from these cells were necessary to spur hair growth in mice, according to research published in the Sept. 2 issue of the journal Cell.
Monday, March 28, 2011
Signal uncovered to help control when stem cells become fat cells
Source: Stanford University Medical Center
Date: March 28, 2011
Summary:
A research team at the Stanford University School of Medicine and UC-San Francisco has uncovered a molecular signal that plays an important role in directing one type of “adult” stem cells to mature into fat cells. The finding could help scientists design better drugs for type-2 diabetes and other diseases associated with obesity. And it may eventually lead to therapies for disorders of low muscle mass, such as pediatric muscular dystrophies or muscle degeneration in the elderly. The study appeared March 18 in the Journal of Biological Chemistry.
Date: March 28, 2011
Summary:
A research team at the Stanford University School of Medicine and UC-San Francisco has uncovered a molecular signal that plays an important role in directing one type of “adult” stem cells to mature into fat cells. The finding could help scientists design better drugs for type-2 diabetes and other diseases associated with obesity. And it may eventually lead to therapies for disorders of low muscle mass, such as pediatric muscular dystrophies or muscle degeneration in the elderly. The study appeared March 18 in the Journal of Biological Chemistry.
Monday, February 28, 2011
Human Stem Cells from Fat Tissue Fuse With Rat Heart Cells and Beat
Source: Federation of American Societies for Experimental Biology
Date: February 28, 2011
Summary:
According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose (fat) tissue with muscle cells from rat hearts. Not only did these cells "talk" to form new muscle cells altogether, but they actually beat.
Using newborn rats, scientists studied the combination of rat heart muscle cells (cardiomyocytes) and human adipose (fat) stem cells derived from human subcutaneous adipose tissue. They found that the two fused and formed new heart muscle cells with several nuclei. When kept in a culture environment, these cells beat. These new cells exhibited an ability to compensate for a loss of cardiomyocytes as following a myocardial infarction, via fusion with cardiomyocytes. Furthermore, this study shows that contrary to previous findings suggesting that genetic modification of certain embryonic genes in adult stem cells is required as a prerequisite for turning into heart cells, the human stem cells used in this study were not genetically modified.
Date: February 28, 2011
Summary:
According to new research published online in The FASEB Journal, scientists have successfully fused human stem cells derived from subcutaneous adipose (fat) tissue with muscle cells from rat hearts. Not only did these cells "talk" to form new muscle cells altogether, but they actually beat.
Using newborn rats, scientists studied the combination of rat heart muscle cells (cardiomyocytes) and human adipose (fat) stem cells derived from human subcutaneous adipose tissue. They found that the two fused and formed new heart muscle cells with several nuclei. When kept in a culture environment, these cells beat. These new cells exhibited an ability to compensate for a loss of cardiomyocytes as following a myocardial infarction, via fusion with cardiomyocytes. Furthermore, this study shows that contrary to previous findings suggesting that genetic modification of certain embryonic genes in adult stem cells is required as a prerequisite for turning into heart cells, the human stem cells used in this study were not genetically modified.
Wednesday, June 30, 2010
Stem cells from fat may help heal bone
Source: University of California - Davis
Date: June 30, 2010
Summary:
Wounded soldiers may one day be treated with stem cells from their own fat using a method under development at UC Davis. The method employs a gel-like material to encourage stem cells from fat to regenerate damaged bone. The stem cells have been shown to stimulate the growth of small blood vessels in developing bone, encouraging healing. The gel keeps the stem cells at the injury site; as the bone heals, the gel breaks down.
Date: June 30, 2010
Summary:
Wounded soldiers may one day be treated with stem cells from their own fat using a method under development at UC Davis. The method employs a gel-like material to encourage stem cells from fat to regenerate damaged bone. The stem cells have been shown to stimulate the growth of small blood vessels in developing bone, encouraging healing. The gel keeps the stem cells at the injury site; as the bone heals, the gel breaks down.
Monday, January 18, 2010
“Jekyll and Hyde” cell may hold key to muscular dystrophy, fibrosis treatment: UBC research
Source:University of British Columbia
Date: January 18, 2010
Summary:
A team of University of British Columbia researchers has identified fat-producing cells that possess “dual-personalities” and may further the development of treatments for muscle diseases such as muscular dystrophy and fibrosis. The team found a new type of fibro/adipogenic progenitors, or FAPs, that generate fatty fibrous tissues when transplanted into damaged muscles in mice. Progenitors are similar to stem cells in their capacity to differentiate, but are limited in the number of times they can divide. The findings are published in the current issue of Nature Cell Biology.
Date: January 18, 2010
Summary:
A team of University of British Columbia researchers has identified fat-producing cells that possess “dual-personalities” and may further the development of treatments for muscle diseases such as muscular dystrophy and fibrosis. The team found a new type of fibro/adipogenic progenitors, or FAPs, that generate fatty fibrous tissues when transplanted into damaged muscles in mice. Progenitors are similar to stem cells in their capacity to differentiate, but are limited in the number of times they can divide. The findings are published in the current issue of Nature Cell Biology.
Wednesday, September 09, 2009
Coverage Summary of Conversion Of Fat Stem Cells Into Pluripotent Stem Cells
Below is a summary of news coverage of the recent announcement by researchers at Stanford University Medical Center that adult stem cells from fat were converted to pluripotent stem cells:
Medical News Today, 09 September 2009 - 2:00 PDT: "Making Stem Cells From Liposuction Leftovers Is Easier Say Researchers":
Writing in a new study, US researchers said it was easier and just as safe to make stem cells from fat cells freshly isolated from patients, for instance from cells present in liposuction "leftovers", than it was to make them from skin cells as other studies have done recently. The study was the work of researchers at the Stanford University School of Medicine in California and was published online ahead of print on 8 September in the Proceedings of the National Academy of Sciences, PNAS.
Scientific American, September 8, 2009: "Induced Pluripotent Stem Cells Created from Fat Cells":
The standard way to make induced pluripotent stem (iPS) cells for medical research is to scrape skin cells and mix up their internal clocks, coaxing them back into pluripotency over a matter of weeks. But now researchers at the Stanford University School of Medicine have turned their attention to another cell type in abundant supply: fat cells. The team of cardiologists and plastic surgeons found adipose fat cells to be much more efficient than skin cells at turning back into stem cells.
Los Angeles Times, September 8, 2009: "Stem cell researchers uncover promise in fat":
That fat you've been carrying on your hips, thighs and belly can be transformed with relative ease into cells that eventually may be capable of repairing a wide range of your damaged or diseased tissues, according to a new report by Stanford University researchers. Stem cells found in fat deposits, it turns out, are more primitive than are many adult stem cells harvested from tissues such as skin and blood. With comparatively less effort than is required to make, for instance, a stem cell derived from skin return to an undifferentiated cell form, fat cells can be reprogrammed to become muscle, neuron and stomach lining cells, finds a new study slated for publication in the Proceedings of the National Academy of Sciences."
Reuters, September 8, 2009, 6:48pm EDT: "Liposuction leftovers make easy stem cells: study":
Fat sucked out of chunky thighs or flabby bellies might provide an easy source of stem cells made using new and promising technology, U.S. researchers reported on Tuesday. They found immature fat cells in the material removed during liposuction were easy to transform into cells called induced pluripotent stem cells, or iPS cells. They were easier to work with than the skin cells usually used to make iPS cells, the team at Stanford University's School of Medicine in California reported in the Proceedings of the National Academy of Sciences. IPS cells are made using genes that take them back in time to a more immature and pliable state. They can then be re-directed to form heart cells, bone cells, brain cells or any other type of desired cell.
Nature, 7 September 2009: "Flab and freckles could advance stem cell research":
"Fat cells and pigment-producing skin cells can be reprogrammed into stem cells much faster and more efficiently than the skin cells that are usually used — suggesting large bellies and little black moles could provide much-needed material for deriving patient-specific stem cells."
San Jose Mercury News, September 7, 2009: "Stanford scientists turn liposuction leftovers into embryonic-like stem cells":
In medicine's version of winning the daily double, Stanford University researchers took ordinary fat cells and transformed them into what are effectively embryonic stem cells — those versatile cellular building blocks that can morph into a variety of tissues. Scientists warn it's too soon to use excess fat to cure disease. But in theory, it would allow people to grow personalized replacement parts for ailing organs. And it avoids the use of embryos, which has embroiled the field in political and ethical debates.
Bloomberg News, September 7, 2009: "Liposuction Fat Turns to Stem Cells Quicker Than Skin in Study":
Human fat, widely available and easily harvested with liposuction, morphed into stem cells more efficiently than skin cells in a study, giving scientists an alternative to the use of embryonic cells. Three years ago, Shinya Yamanaka, of Kyoto University in Japan, showed that skin cells could be genetically manipulated to become any other cell type, much like embryonic stem cells. This process was hailed as avoiding the destruction of embryos and letting scientists create new therapies by making stem cells from patients who are ill.
Since then, researchers have sought to overcome two drawbacks to Yamanaka’s method. One is that the viruses and genes used to reprogram skin cells can trigger tumor growth. The second is that the process is inefficient, with less than 1 percent of skin cells becoming all-purpose cells. The new research, published today in the Proceedings of the National Academy of Sciences, may solve the second problem.
Medical News Today, 09 September 2009 - 2:00 PDT: "Making Stem Cells From Liposuction Leftovers Is Easier Say Researchers":
Writing in a new study, US researchers said it was easier and just as safe to make stem cells from fat cells freshly isolated from patients, for instance from cells present in liposuction "leftovers", than it was to make them from skin cells as other studies have done recently. The study was the work of researchers at the Stanford University School of Medicine in California and was published online ahead of print on 8 September in the Proceedings of the National Academy of Sciences, PNAS.
Scientific American, September 8, 2009: "Induced Pluripotent Stem Cells Created from Fat Cells":
The standard way to make induced pluripotent stem (iPS) cells for medical research is to scrape skin cells and mix up their internal clocks, coaxing them back into pluripotency over a matter of weeks. But now researchers at the Stanford University School of Medicine have turned their attention to another cell type in abundant supply: fat cells. The team of cardiologists and plastic surgeons found adipose fat cells to be much more efficient than skin cells at turning back into stem cells.
Los Angeles Times, September 8, 2009: "Stem cell researchers uncover promise in fat":
That fat you've been carrying on your hips, thighs and belly can be transformed with relative ease into cells that eventually may be capable of repairing a wide range of your damaged or diseased tissues, according to a new report by Stanford University researchers. Stem cells found in fat deposits, it turns out, are more primitive than are many adult stem cells harvested from tissues such as skin and blood. With comparatively less effort than is required to make, for instance, a stem cell derived from skin return to an undifferentiated cell form, fat cells can be reprogrammed to become muscle, neuron and stomach lining cells, finds a new study slated for publication in the Proceedings of the National Academy of Sciences."
Reuters, September 8, 2009, 6:48pm EDT: "Liposuction leftovers make easy stem cells: study":
Fat sucked out of chunky thighs or flabby bellies might provide an easy source of stem cells made using new and promising technology, U.S. researchers reported on Tuesday. They found immature fat cells in the material removed during liposuction were easy to transform into cells called induced pluripotent stem cells, or iPS cells. They were easier to work with than the skin cells usually used to make iPS cells, the team at Stanford University's School of Medicine in California reported in the Proceedings of the National Academy of Sciences. IPS cells are made using genes that take them back in time to a more immature and pliable state. They can then be re-directed to form heart cells, bone cells, brain cells or any other type of desired cell.
Nature, 7 September 2009: "Flab and freckles could advance stem cell research":
"Fat cells and pigment-producing skin cells can be reprogrammed into stem cells much faster and more efficiently than the skin cells that are usually used — suggesting large bellies and little black moles could provide much-needed material for deriving patient-specific stem cells."
San Jose Mercury News, September 7, 2009: "Stanford scientists turn liposuction leftovers into embryonic-like stem cells":
In medicine's version of winning the daily double, Stanford University researchers took ordinary fat cells and transformed them into what are effectively embryonic stem cells — those versatile cellular building blocks that can morph into a variety of tissues. Scientists warn it's too soon to use excess fat to cure disease. But in theory, it would allow people to grow personalized replacement parts for ailing organs. And it avoids the use of embryos, which has embroiled the field in political and ethical debates.
Bloomberg News, September 7, 2009: "Liposuction Fat Turns to Stem Cells Quicker Than Skin in Study":
Human fat, widely available and easily harvested with liposuction, morphed into stem cells more efficiently than skin cells in a study, giving scientists an alternative to the use of embryonic cells. Three years ago, Shinya Yamanaka, of Kyoto University in Japan, showed that skin cells could be genetically manipulated to become any other cell type, much like embryonic stem cells. This process was hailed as avoiding the destruction of embryos and letting scientists create new therapies by making stem cells from patients who are ill.
Since then, researchers have sought to overcome two drawbacks to Yamanaka’s method. One is that the viruses and genes used to reprogram skin cells can trigger tumor growth. The second is that the process is inefficient, with less than 1 percent of skin cells becoming all-purpose cells. The new research, published today in the Proceedings of the National Academy of Sciences, may solve the second problem.
Monday, September 07, 2009
'Liposuction Leftovers' Easily Converted To Induced Pluripotent Stem Cells
Source: Stanford University Medical Center
Date: September 7, 2009
Summary:
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers, according to a new study from Stanford’s School of Medicine. The fact that the cells can also be converted without the need for mouse-derived “feeder cells” may make them an ideal starting material for human therapies. Feeder cells are often used when growing human skin cells outside the body, but physicians worry that cross-species contamination could make them unsuitable for human use. The findings will be published online Sept. 7 in the Proceedings of the National Academy of Sciences.
Date: September 7, 2009
Summary:
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers, according to a new study from Stanford’s School of Medicine. The fact that the cells can also be converted without the need for mouse-derived “feeder cells” may make them an ideal starting material for human therapies. Feeder cells are often used when growing human skin cells outside the body, but physicians worry that cross-species contamination could make them unsuitable for human use. The findings will be published online Sept. 7 in the Proceedings of the National Academy of Sciences.
Thursday, February 26, 2009
From Stem Cells To New Organs: Scientists Cross Threshold In Regenerative Medicine
Source: Federation of American Societies for Experimental Biology
Date: February 26, 2009
Summary:
By now, most people have read stories about how to "grow your own organs" using stem cells is just a breakthrough away. Despite the hype, this breakthrough has been elusive. A new report published in the March 2009 issue of The FASEB Journal brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a "scaffolding" material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection.
Date: February 26, 2009
Summary:
By now, most people have read stories about how to "grow your own organs" using stem cells is just a breakthrough away. Despite the hype, this breakthrough has been elusive. A new report published in the March 2009 issue of The FASEB Journal brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a "scaffolding" material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection.
Thursday, December 11, 2008
Transplanted Fat Cells Restore Function After Spinal Cord Injury
Source: Cell Transplantation
December 11, 2008
Summary:
Fat cells, plentiful and easily obtained from adipose tissues without discomfort and grown under culture conditions as de-differentiated fat cells (DFAT), have been for the first time shown to successfully differentiate into neuronal cells in in vivo tests. According to the study's lead researcher, Dr. Yuki Ohta of the Institute of Medical Science, St. Mariana University School of Medicine, Kawasaki, Japan, adipose-derived stem/stromal cells have in the past been shown to differentiate into neuronal cells in an in vitro setting. In their study, for the first time fat cells have been shown to successfully differentiate into neuronal cells in in vivo tests. The fat cells are grown under culture conditions that result in them becoming de-differentiated fat (DFAT) cells. This study was published in Cell Transplantation (Vol.17, No. 8.)
December 11, 2008
Summary:
Fat cells, plentiful and easily obtained from adipose tissues without discomfort and grown under culture conditions as de-differentiated fat cells (DFAT), have been for the first time shown to successfully differentiate into neuronal cells in in vivo tests. According to the study's lead researcher, Dr. Yuki Ohta of the Institute of Medical Science, St. Mariana University School of Medicine, Kawasaki, Japan, adipose-derived stem/stromal cells have in the past been shown to differentiate into neuronal cells in an in vitro setting. In their study, for the first time fat cells have been shown to successfully differentiate into neuronal cells in in vivo tests. The fat cells are grown under culture conditions that result in them becoming de-differentiated fat (DFAT) cells. This study was published in Cell Transplantation (Vol.17, No. 8.)
Wednesday, December 03, 2008
New 'control knobs' for stem cells identified
Source: Tufts University
Date: December 3, 2008
Summary:
Natural changes in voltage that occur across the membrane of adult human stem cells are a powerful controlling factor in the process by which these stem cells differentiate, according to research published by Tufts University scientists in the November 17, 2008, issue of PLoS ONE. The Tufts researchers studied the changes in membrane potential (voltage across the membrane) shown by human mesenchymal stem cells (hMSCs) obtained from donor bone marrow as the hMSCs were differentiating into fat and bone cells. They found that hyperpolarization (increased difference between the voltage in the interior and exterior of a cell) was characteristic of differentiated cells compared with undifferentiated cells and that hMSCs show different membrane potential profiles during bone vs. fat differentiation.
Date: December 3, 2008
Summary:
Natural changes in voltage that occur across the membrane of adult human stem cells are a powerful controlling factor in the process by which these stem cells differentiate, according to research published by Tufts University scientists in the November 17, 2008, issue of PLoS ONE. The Tufts researchers studied the changes in membrane potential (voltage across the membrane) shown by human mesenchymal stem cells (hMSCs) obtained from donor bone marrow as the hMSCs were differentiating into fat and bone cells. They found that hyperpolarization (increased difference between the voltage in the interior and exterior of a cell) was characteristic of differentiated cells compared with undifferentiated cells and that hMSCs show different membrane potential profiles during bone vs. fat differentiation.
Friday, August 08, 2008
Scientists uncover the key to controlling how stem cells develop
Source: McMaster University
Date: August 7, 2008
Summary:
The results of a new study involving a McMaster University researcher provide insight into how scientists might control human embryonic stem cell differentiation. In collaboration with researchers from SickKids and Mount Sinai hospitals, Dr. Jon Draper, a scientist in the McMaster Stem Cell and Cancer Research Institute, focused on producing early endoderm cells from human embryonic stem cells. The research is published in the August issue of Cell Stem Cell, a Cell Press journal.
Date: August 7, 2008
Summary:
The results of a new study involving a McMaster University researcher provide insight into how scientists might control human embryonic stem cell differentiation. In collaboration with researchers from SickKids and Mount Sinai hospitals, Dr. Jon Draper, a scientist in the McMaster Stem Cell and Cancer Research Institute, focused on producing early endoderm cells from human embryonic stem cells. The research is published in the August issue of Cell Stem Cell, a Cell Press journal.
Wednesday, July 23, 2008
Want A Reason to Love Your Lower Belly Fat? Study Finds Some Areas of the Body Have Greater Concentrations of Stem Cells
Source: American Society of Plastic Surgeons
Date: July 23, 2008
Summary:
Fat removed from the lower abdomen and inner thigh through liposuction was found to be an excellent source of stem cells, with higher stem cell concentrations than other areas of the body, reports a Brazilian-based study in August's Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). This is the first study of its kind to examine whether fat tissues from different areas of the body vary in stem cell concentration.
In the study, 23 female patients having liposuction in at least four different body areas agreed to have their fat isolated for adult stem cells and analyzed to determine stem cell concentrations. The body areas that were liposuctioned were: lower abdomen, upper abdomen, inner knee, inner thigh, flank and hips.
The study results found a significant difference in stem cell concentrations in different areas of the body. A major finding was that the concentration of stem cells was greatest in the lower abdomen and inner thighs. Interestingly, stem cell concentration in the lower abdomen was five times greater than in the upper abdomen.
Date: July 23, 2008
Summary:
Fat removed from the lower abdomen and inner thigh through liposuction was found to be an excellent source of stem cells, with higher stem cell concentrations than other areas of the body, reports a Brazilian-based study in August's Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS). This is the first study of its kind to examine whether fat tissues from different areas of the body vary in stem cell concentration.
In the study, 23 female patients having liposuction in at least four different body areas agreed to have their fat isolated for adult stem cells and analyzed to determine stem cell concentrations. The body areas that were liposuctioned were: lower abdomen, upper abdomen, inner knee, inner thigh, flank and hips.
The study results found a significant difference in stem cell concentrations in different areas of the body. A major finding was that the concentration of stem cells was greatest in the lower abdomen and inner thighs. Interestingly, stem cell concentration in the lower abdomen was five times greater than in the upper abdomen.
Tuesday, May 13, 2008
Novel mechanisms controlling insulin release and fat deposition discovered
Source: Karolinska Institutet
Date: May 13, 2008
Summary
Scientists at the Swedish medical university Karolinska Institutet have in two recent studies shown that a receptor called ALK7 plays important roles in the regulation of body fat deposition as well as the release of insulin from beta-cells in the pancreas. These findings have implications for the development of treatments against diabetes and obesity.
Date: May 13, 2008
Summary
Scientists at the Swedish medical university Karolinska Institutet have in two recent studies shown that a receptor called ALK7 plays important roles in the regulation of body fat deposition as well as the release of insulin from beta-cells in the pancreas. These findings have implications for the development of treatments against diabetes and obesity.
Friday, February 01, 2008
Finnish patient gets new jaw from own stem cells
Source: Reuters
Posted: February 1, 2008 1:46pm EST
Summary:
Reuters reports scientists have created a new jaw made from bone transplanted derived from a patient's own fat tissue:
"Scientists in Finland said they had replaced a 65-year-old patient's upper jaw with a bone transplant cultivated from stem cells isolated from his own fatty tissue and grown inside his abdomen. Researchers said on Friday the breakthrough opened up new ways to treat severe tissue damage and made the prospect of custom-made living spares parts for humans a step closer to reality."
Posted: February 1, 2008 1:46pm EST
Summary:
Reuters reports scientists have created a new jaw made from bone transplanted derived from a patient's own fat tissue:
"Scientists in Finland said they had replaced a 65-year-old patient's upper jaw with a bone transplant cultivated from stem cells isolated from his own fatty tissue and grown inside his abdomen. Researchers said on Friday the breakthrough opened up new ways to treat severe tissue damage and made the prospect of custom-made living spares parts for humans a step closer to reality."
Wednesday, January 30, 2008
First Patients Treated in Cytori's Stem & Regenerative Cell Heart Attack Study
Source: Cytori Therapeutics
Date: January 30, 2008
Summary:
In an official company news release, Cytori Therapeutics, a biotechnology company in the field of adult stem cell research, announced the the treatment of the first patients participating in its clinical trial using Adult adipose (fat) stem and regenerative cells to treat heart attacks:
" Cytori Therapeutics (NASDAQ: CYTX) enrolled the first two patients in a clinical trial using adipose-derived stem and regenerative cells in the treatment of heart attack. In this trial, patients' cells are made available using Cytori's Celution™ System, a real-time cell processing device. One patient has been enrolled in each trial center, Hospital Universitario Gregorio Marañón in Madrid, Spain, and Thoraxcenter, Erasmus Medical Center in Rotterdam, The Netherlands."
Date: January 30, 2008
Summary:
In an official company news release, Cytori Therapeutics, a biotechnology company in the field of adult stem cell research, announced the the treatment of the first patients participating in its clinical trial using Adult adipose (fat) stem and regenerative cells to treat heart attacks:
" Cytori Therapeutics (NASDAQ: CYTX) enrolled the first two patients in a clinical trial using adipose-derived stem and regenerative cells in the treatment of heart attack. In this trial, patients' cells are made available using Cytori's Celution™ System, a real-time cell processing device. One patient has been enrolled in each trial center, Hospital Universitario Gregorio Marañón in Madrid, Spain, and Thoraxcenter, Erasmus Medical Center in Rotterdam, The Netherlands."
Sunday, December 16, 2007
Fat used to repair breasts
Source: Associated Press
Date: December 16, 2007
Summary:
The Associated Press reports on a new procedure using fat stem cells to repair breast defects:
"For the first time, doctors have used stem cells from liposuctioned fat to fix breast defects in women who have had cancerous lumps removed. The approach, still experimental, holds promise for millions of women left with cratered areas and breasts that look very different from each other after cancer surgery. It might also be a way to augment healthy breasts without using artificial implants."
Date: December 16, 2007
Summary:
The Associated Press reports on a new procedure using fat stem cells to repair breast defects:
"For the first time, doctors have used stem cells from liposuctioned fat to fix breast defects in women who have had cancerous lumps removed. The approach, still experimental, holds promise for millions of women left with cratered areas and breasts that look very different from each other after cancer surgery. It might also be a way to augment healthy breasts without using artificial implants."
Tuesday, November 06, 2007
Fat cells send message that aids insulin secretion
Source: Washington University School of Medicine.
Date: November 6, 2007
Summary:
The body's fat cells help the pancreas do its job of secreting insulin, according to new research. This previously unrecognized process ultimately could lead to new methods to improve glucose metabolism in type 2 diabetic or insulin-resistant people. In a study using laboratory mice, published in the November 7, 2007 issue of Cell Metabolism, scientists at the Washington University School of Medicine report that fat cells release a protein that aids insulin secretion from pancreatic beta cells, which are the sole source of insulin. The protein is an enzyme that the pancreatic cells themselves produce in only minimal amounts. The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells.
Date: November 6, 2007
Summary:
The body's fat cells help the pancreas do its job of secreting insulin, according to new research. This previously unrecognized process ultimately could lead to new methods to improve glucose metabolism in type 2 diabetic or insulin-resistant people. In a study using laboratory mice, published in the November 7, 2007 issue of Cell Metabolism, scientists at the Washington University School of Medicine report that fat cells release a protein that aids insulin secretion from pancreatic beta cells, which are the sole source of insulin. The protein is an enzyme that the pancreatic cells themselves produce in only minimal amounts. The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells.
Sunday, October 21, 2007
Stem Cells From Patient's Fat Used To Grow New Nerves
Source: Medical News Today
Article Date: 21 October 2007 - 0:00 PDT
Summary:
Stem cells from a patient's fat may be used to create new nerves that can repair severed peripheral nerves (nerves outside the spinal cord), say scientists from Manchester University, England. The researchers say this route for creating new nerves could be part of medical practice by the year 2011.
Article Date: 21 October 2007 - 0:00 PDT
Summary:
Stem cells from a patient's fat may be used to create new nerves that can repair severed peripheral nerves (nerves outside the spinal cord), say scientists from Manchester University, England. The researchers say this route for creating new nerves could be part of medical practice by the year 2011.
Friday, October 19, 2007
New nerves grown from fat cells
Source: BBC News
Posted: 19 October 2007, 23:48 GMT 00:48 UK
Summary:
BBC News reports British scientists have transformed stem cells from fat into nerve cells:
New nerves grown from stem cells taken from a patient's fat could be available by 2011, researchers have said. They could potentially be used to repair peripheral nerves left severed by surgery or accidents. Manchester University scientists plan to place the new nerve tissue inside a biodegradable plastic tube, which can be used to rejoin the two broken ends."
Posted: 19 October 2007, 23:48 GMT 00:48 UK
Summary:
BBC News reports British scientists have transformed stem cells from fat into nerve cells:
New nerves grown from stem cells taken from a patient's fat could be available by 2011, researchers have said. They could potentially be used to repair peripheral nerves left severed by surgery or accidents. Manchester University scientists plan to place the new nerve tissue inside a biodegradable plastic tube, which can be used to rejoin the two broken ends."
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