Wednesday, February 23, 2005

Scientists Identify Stem Cell On/Off Switch

Source: HealthDay News
Date: February 23, 2005

Summary:

In experiments with mice, scientists believe they've discovered a new class of gene signals that either prevent or permit stem cells to develop into specific cell types. This is an important advance because to keep stem cells useful therapeutically, doctors will have to preserve them as undifferentiated stem cells for as long as possible.

Newly-discovered Class Of Genes Determines -- And Restricts -- Stem Cell Fate

Source: University Of Pennsylvania Medical Center
Date: February 23, 2005

Summary:

Research on adult stem cells found in the skin hints at a new class of genes, according to a study from investigators at the University of Pennsylvania School of Medicine. These genes dubbed pangenes can both govern a stem cell's fate and put a hold on future differentiation until the time is right. Understanding the molecular control of these genes has implications for therapies that involve tissue regeneration.

Stem Cell Therapy For Spinal Injury

Source: Karolinska Institutet
Date: February 23, 2005

Summary:

Researchers at Karolinska Institutet have shown how the transplantation of stem cells improves recovery from spinal injury. However, a painful condition can also develop, which can be prevented if the stem cells are supplemented with a certain gene that controls their maturing process. The results are important for planning of stem cell therapy trials on patients with spinal injury.

Thursday, February 10, 2005

Research May Hold Promise For Treating Alzheimer's

Source: University Of Central Florida
Date: February 10, 2005

Summary:

A compound similar to the components of DNA may improve the chances that stem cells transplanted from a patient's bone marrow to the brain will take over the functions of damaged cells and help treat Alzheimer's disease and other neurological illnesses. A research team at the University of Central Florida found that treating bone marrow cells in laboratory cultures with bromodeoxyuridine, a compound that becomes part of DNA, made adult human stem cells more likely to develop as brain cells after they were implanted in adult rat brains.