Source: Advanced Cell Technology, Inc.
Date: June 29, 2005
Summary:
WORCESTER, Mass. -- Advanced Cell Technology, Inc. and its collaborators reported the long-term transplantation of clone-derived stem cells in an animal model of aging. In this study, the cloned-derived stem cells showed an exponential (tenfold) competitive advantage over adult stem cells.
Wednesday, June 29, 2005
Monday, June 27, 2005
Rebooted cells tackle ethical concerns: Fusion technique resets adult skin cells to embryonic state
Source: Nature
Date: 27 June 2005
Summary:
A new study published in the journal Nature describes an experiment attempting to give adult stem cells the properties of embryonic stem cells by fusing adult skin cells and embryonic stem cells:
"Scientists who want to study the special properties of stem cells may be able to use a new technique to avoid some of the practical and ethical pitfalls of stem-cell research. Scientists at the Harvard Stem Cell Institute have fused a human embryonic stem cell to an adult skin cell. They showed that the embryonic stem cell 'reprogrammed' the skin cell's nucleus, causing the skin cell to start behaving like a youthful, embryonic stem cell."
Date: 27 June 2005
Summary:
A new study published in the journal Nature describes an experiment attempting to give adult stem cells the properties of embryonic stem cells by fusing adult skin cells and embryonic stem cells:
"Scientists who want to study the special properties of stem cells may be able to use a new technique to avoid some of the practical and ethical pitfalls of stem-cell research. Scientists at the Harvard Stem Cell Institute have fused a human embryonic stem cell to an adult skin cell. They showed that the embryonic stem cell 'reprogrammed' the skin cell's nucleus, causing the skin cell to start behaving like a youthful, embryonic stem cell."
A Step Forward In Stem Cell Research
Source: Memorial Sloan-Kettering Cancer Center
Posted: June 27, 2005
Summary:
Investigators from Memorial Sloan-Kettering Cancer Center (MSKCC) have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells (HESCs). Mesenchymal precursor cells are capable of giving rise to fat, cartilage, bone, and skeletal muscle cells, and may potentially be used for regenerative stem cell therapy in bone, cartilage, or muscle replacement.
Posted: June 27, 2005
Summary:
Investigators from Memorial Sloan-Kettering Cancer Center (MSKCC) have used new techniques in the laboratory that allowed them for the first time to derive unlimited numbers of purified mesenchymal precursor cells from human embryonic stem cells (HESCs). Mesenchymal precursor cells are capable of giving rise to fat, cartilage, bone, and skeletal muscle cells, and may potentially be used for regenerative stem cell therapy in bone, cartilage, or muscle replacement.
Friday, June 24, 2005
Neuroglial activation in Niemann–Pick Type C mice is suppressed by intracerebral transplantation of bone marrow-derived mesenchymal stem cells
Source: Neuroscience Letters
Volume 381, Issue 3, 24 June 2005, Pages 234-236
Abstract:
Glial activation is thought to play a key role in pathogenesis of neurodegenerative disorders. Here we show that direct transplantation of bone marrow-derived mesenchymal stem cells (BM-MSC) results in alleviation of inflammatory responses associated with the cerebellum of Niemann–Pick disease Type C (NP-C) model mice. Immunohistochemical examinations using glial fibrillary acidic protein (GFAP) and F4/80 antibodies revealed that BM-MSC transplantation reduced significantly both of astocytic and microglial activations in the cerebellum of NP-C mice. Expression of macrophage colony stimulating factor (M-CSF), a microglial activator, was also considerably down-regulated by the BM-MSC transplantation. These findings suggest that BM-MSC transplantation may have potential for a therapeutic role in the treatment of NP-C and other neurodegenerative brain disorders.
Volume 381, Issue 3, 24 June 2005, Pages 234-236
Abstract:
Glial activation is thought to play a key role in pathogenesis of neurodegenerative disorders. Here we show that direct transplantation of bone marrow-derived mesenchymal stem cells (BM-MSC) results in alleviation of inflammatory responses associated with the cerebellum of Niemann–Pick disease Type C (NP-C) model mice. Immunohistochemical examinations using glial fibrillary acidic protein (GFAP) and F4/80 antibodies revealed that BM-MSC transplantation reduced significantly both of astocytic and microglial activations in the cerebellum of NP-C mice. Expression of macrophage colony stimulating factor (M-CSF), a microglial activator, was also considerably down-regulated by the BM-MSC transplantation. These findings suggest that BM-MSC transplantation may have potential for a therapeutic role in the treatment of NP-C and other neurodegenerative brain disorders.
Study: Adult stem cells promising
Source: Pittsburgh Tribune-Review
Date: June 24, 2005
Summary:
Children's Hospital of Pittsburgh researchers announced they have discovered a population of stem cells isolated from mouse muscle with the same ability to multiply as stem cells harvested from human embryos.
Date: June 24, 2005
Summary:
Children's Hospital of Pittsburgh researchers announced they have discovered a population of stem cells isolated from mouse muscle with the same ability to multiply as stem cells harvested from human embryos.
Thursday, June 23, 2005
Breakthrough Study at Children's Hospital of Pittsburgh Finds Adult Stem Cells Show Same Ability to Self-Renew as Embryonic
Source: Children's Hospital of Pittsburgh
Date: June 23, 2005
Summary:
In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post- natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role. Researchers were able to expand post-natal stem cells to a population level comparable to that reached by researchers using embryonic stem cells.
Date: June 23, 2005
Summary:
In a ground-breaking study, scientists at Children's Hospital of Pittsburgh have discovered that adult, or post- natal, stem cells have the same ability as embryonic stem cells to multiply, a previously unknown characteristic indicating that post-natal stem cells may play an important therapeutic role. Researchers were able to expand post-natal stem cells to a population level comparable to that reached by researchers using embryonic stem cells.
Wake Forest research shows stem cells can be gleaned from skin
Source: The Business Journal
Date: June 23, 2005
Summary:
In what could be a major scientific leap, Dr. Anthony Atala revealed Thursday that his Wake Forest University Institute for Regenerative Medicine laboratory in Winston-Salem has successfully taken stem cells from skin and grown them into new tissues.
Date: June 23, 2005
Summary:
In what could be a major scientific leap, Dr. Anthony Atala revealed Thursday that his Wake Forest University Institute for Regenerative Medicine laboratory in Winston-Salem has successfully taken stem cells from skin and grown them into new tissues.
Researchers Grow Stem Cells From Human Skin
Source: Wake Forest University Baptist Medical Center
Posted: June 23, 2005
Summary:
WINSTON-SALEM, N.C. – Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells. The study, one of the first studies to show the ability of a single adult stem cell to become multiple tissue types, is reported this week in Stem Cells and Development.
Posted: June 23, 2005
Summary:
WINSTON-SALEM, N.C. – Researchers at Wake Forest University School of Medicine have successfully isolated stem cells from human skin, expanded them in the laboratory and coaxed them into becoming fat, muscle and bone cells. The study, one of the first studies to show the ability of a single adult stem cell to become multiple tissue types, is reported this week in Stem Cells and Development.
Sunday, June 19, 2005
Breakthrough Isolating Embryo-quality Stem Cells From Blood
Source: Institute of Physics
Posted: June 19, 2005
Summary:
A major breakthrough in stem cell research – a new tool that could allow scientists to harvest stem cells ethically - was announced recently at the Institute of Physics’ conference Physics 2005. Professors from the University of Leipzig have developed a procedure that can extract and isolate embryo-quality stem cells from adult blood for the first time. This new technique could unlock the stem cell revolution and stimulate a boom in medical research using stem cells.
Posted: June 19, 2005
Summary:
A major breakthrough in stem cell research – a new tool that could allow scientists to harvest stem cells ethically - was announced recently at the Institute of Physics’ conference Physics 2005. Professors from the University of Leipzig have developed a procedure that can extract and isolate embryo-quality stem cells from adult blood for the first time. This new technique could unlock the stem cell revolution and stimulate a boom in medical research using stem cells.
Breakthrough Isolating Embryo-quality Stem Cells From Blood
Source: Institute of Physics
Date: June 19, 2005
Summary:
A major breakthrough in stem cell research – a new tool that could allow scientists to harvest stem cells ethically - was announced at the Institute of Physics’ conference Physics 2005. Professor Josef Käs and Dr Jochen Guck from the University of Leipzig have developed a procedure that can extract and isolate embryo-quality stem cells from adult blood for the first time. This new technique could unlock the stem cell revolution and stimulate a boom in medical research using stem cells.
Date: June 19, 2005
Summary:
A major breakthrough in stem cell research – a new tool that could allow scientists to harvest stem cells ethically - was announced at the Institute of Physics’ conference Physics 2005. Professor Josef Käs and Dr Jochen Guck from the University of Leipzig have developed a procedure that can extract and isolate embryo-quality stem cells from adult blood for the first time. This new technique could unlock the stem cell revolution and stimulate a boom in medical research using stem cells.
Monday, June 13, 2005
Scientists grow large batches of brain stem cells: Discovery could lead to new treatments for neurological diseases
Source: Reuters
Posted: June 13, 2005 5:06 p.m. ET
Summary:
WASHINGTON - Scientists working in mice said they had found a way to identify master cells in the brain and grow them in large batches — a potential way of helping patients grow their own brain tissue transplants. The scientists said they had found a process to make the cells multiply, which would be crucial in fighting degenerative brain diseases like Parkinson’s and Huntington’s.
Posted: June 13, 2005 5:06 p.m. ET
Summary:
WASHINGTON - Scientists working in mice said they had found a way to identify master cells in the brain and grow them in large batches — a potential way of helping patients grow their own brain tissue transplants. The scientists said they had found a process to make the cells multiply, which would be crucial in fighting degenerative brain diseases like Parkinson’s and Huntington’s.
Wednesday, June 08, 2005
Scientists find key to stem cell immortality: MicroRNAs short-circuit
Source: MSNBC News
Posted: June 8, 2005 9:26 p.m. ET
Summary:
MSNBC News reports on a new finding about the role of microRNA's in the regulation of both normal and cancer stem cells:
"Researchers report in the journal Nature that microRNAs — tiny snippets of genetic material that have now been linked to growth regulation in normal cells as well as cancer growth in abnormal cells — appear to shut off the "stop signals" or brakes that would normally tell cells to stop dividing."
Posted: June 8, 2005 9:26 p.m. ET
Summary:
MSNBC News reports on a new finding about the role of microRNA's in the regulation of both normal and cancer stem cells:
"Researchers report in the journal Nature that microRNAs — tiny snippets of genetic material that have now been linked to growth regulation in normal cells as well as cancer growth in abnormal cells — appear to shut off the "stop signals" or brakes that would normally tell cells to stop dividing."
Czech Scientist Sustain Human Stem Cells in Original 'Blank' State
Source: CzechInvest
Date: June 8, 2005
Summary:
CzechInvest announce the discovery of a way to maintain human embryonic stem cells in their original, undifferentiated state:
"CzechInvest, the Investment and Business Development Agency of the Czech Republic, today announced Czech scientists have recently made significant new breakthroughs in stem cell research. Dr. Petr Dvorak, scientist with the Institute of Experimental Medicine at the Czech Academy of Sciences, will detail the discovery of a potential mechanism that would sustain human stem cells in their original "blank" state. The leading international scientific journal, Stem Cells, is slated to publish these findings in an upcoming issue later this year."
Date: June 8, 2005
Summary:
CzechInvest announce the discovery of a way to maintain human embryonic stem cells in their original, undifferentiated state:
"CzechInvest, the Investment and Business Development Agency of the Czech Republic, today announced Czech scientists have recently made significant new breakthroughs in stem cell research. Dr. Petr Dvorak, scientist with the Institute of Experimental Medicine at the Czech Academy of Sciences, will detail the discovery of a potential mechanism that would sustain human stem cells in their original "blank" state. The leading international scientific journal, Stem Cells, is slated to publish these findings in an upcoming issue later this year."
Team IDs Mechanism For Multiplying Adult Stem Cells
Source: Massachusetts Institute Of Technology
Date: June 8, 2005
Summary:
Researchers have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently. One of the main obstacles with adult stem cell research is that, in order for these cells to be therapeutically useful, researchers need to multiply them in the lab. But when adult stem cells are isolated, they immediately start growing into their designated tissue type, which limits their replication. If scientists could take a liver adult stem cell and multiply it in a dish, without having it form mature liver tissue, more tissue could be made.
Date: June 8, 2005
Summary:
Researchers have discovered a mechanism that might enable scientists to multiply adult stem cells quickly and efficiently. One of the main obstacles with adult stem cell research is that, in order for these cells to be therapeutically useful, researchers need to multiply them in the lab. But when adult stem cells are isolated, they immediately start growing into their designated tissue type, which limits their replication. If scientists could take a liver adult stem cell and multiply it in a dish, without having it form mature liver tissue, more tissue could be made.
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