Date December. 27, 2005
Source: Newsday
Summary:
Scientists at Memorial Sloan-Kettering Cancer Center in Manhattan have developed a stem cell-based gene therapy that targets stem cells and restores effective oxygen delivery, which may cure two pervasive blood disorders. The first round of human trials is expected to begin within six months. Gene therapy is the technique in which a healthy new gene is incorporated into patients' cells to correct a debilitating defect. Scientists report that they have developed a form of gene therapy that targets stem cells and restores effective oxygen delivery.
Tuesday, December 27, 2005
MIT Researcher Finds Neuron Growth In Adult Brain
Source: Massachusetts Institute of Technology
Date: December 27, 2005
Summary:
A researcher at MIT's Picower Institute for Learning and Memory reports that structural remodeling of neurons does in fact occur in mature brains. This finding means that it may one day be possible to grow new cells to replace ones damaged by disease or spinal cord injury.
Date: December 27, 2005
Summary:
A researcher at MIT's Picower Institute for Learning and Memory reports that structural remodeling of neurons does in fact occur in mature brains. This finding means that it may one day be possible to grow new cells to replace ones damaged by disease or spinal cord injury.
Friday, December 23, 2005
New Neurons Take Baby Steps In The Adult Brain
Source: Johns Hopkins Medical Institutions
Date: December 23, 2005
Summary:
In experiments with mice, scientists from Johns Hopkins' Institute for Cell Engineering have discovered the steps required to integrate new neurons into the brain's existing operations. In the first study to show how these "baby" neurons are integrated into the brain's existing networks, the Johns Hopkins researchers show that a brain chemical called GABA readies baby neurons to make connections to old ones.
Date: December 23, 2005
Summary:
In experiments with mice, scientists from Johns Hopkins' Institute for Cell Engineering have discovered the steps required to integrate new neurons into the brain's existing operations. In the first study to show how these "baby" neurons are integrated into the brain's existing networks, the Johns Hopkins researchers show that a brain chemical called GABA readies baby neurons to make connections to old ones.
Thursday, December 22, 2005
A Little Telomerase Isn't Enough: Study Links Length Of Chromosome Ends To A Rare Disease Of Stem Cells
Source: Johns Hopkins Medical Institutions
Posted: December 22, 2005
Summary:
A Johns Hopkins geneticist and her team have discovered a critical link between the health of stem cells and the length of the chromosome ends within them.
Posted: December 22, 2005
Summary:
A Johns Hopkins geneticist and her team have discovered a critical link between the health of stem cells and the length of the chromosome ends within them.
Clinical Trial To Test Stem Cell Approach For Children With Brain Injury
Source: University of Texas Health Science Center at Houston
Date: December 22, 2005
Summary:
A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow. The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic stem cells. As a Phase I clinical trial, the project's first emphasis is to establish the safety of the procedure, with a secondary goal of observing possible therapeutic effects.
Date: December 22, 2005
Summary:
A unique clinical trial will gauge the safety and potential of treating children suffering traumatic brain injury with stem cells derived from their own bone marrow. The clinical trial is the first to apply stem cells to treat traumatic brain injury. It does not involve embryonic stem cells. As a Phase I clinical trial, the project's first emphasis is to establish the safety of the procedure, with a secondary goal of observing possible therapeutic effects.
Monday, December 19, 2005
Stem Cells from Hair Follicles Rival Embryonic Stem Cells in Their Potential for Regenerative Medicine
Source: AntiCancer, Inc.
Posted: December 19, 2005 6:00 am ET
Summary:
Researchers led by a team at AntiCancer, Inc., in San Diego have found that stem cells from hair follicles of mice can be used to rejoin severed nerves in mouse models. Easily accessible hair follicle stem cells, which normally function to form the hair follicle which in turn form the growing hair in all mammals including man, have been shown to have great potential to produce nerve cells and many other types of cells.
Posted: December 19, 2005 6:00 am ET
Summary:
Researchers led by a team at AntiCancer, Inc., in San Diego have found that stem cells from hair follicles of mice can be used to rejoin severed nerves in mouse models. Easily accessible hair follicle stem cells, which normally function to form the hair follicle which in turn form the growing hair in all mammals including man, have been shown to have great potential to produce nerve cells and many other types of cells.
Sunday, December 18, 2005
New hope for arthritis sufferers
Source: BBC NEWS:
Published: 2005/12/18 19:56:44 GMT
Summary:
BBC News reports on an advancement in growing cartilage from adult bone marrow stem cells to attempt to treat arthritis:
"Scientists say they have made a significant step towards finding a new treatment for osteoarthritis. Researchers at Bristol University successfully grew new cartilage from a patient's own stem cells. Experts from Bristol University grew a piece of cartilage using stem cells from the bone marrow of people undergoing hip replacement operations because of the disease. The new technique is expected to overcome problems of transplant rejection because the patient's own cells are used to create the cartilage. Ethical concerns over using human embryos in stem cell research can also be avoided. They hope the technique will allow them to carry out transplants in the future."
Published: 2005/12/18 19:56:44 GMT
Summary:
BBC News reports on an advancement in growing cartilage from adult bone marrow stem cells to attempt to treat arthritis:
"Scientists say they have made a significant step towards finding a new treatment for osteoarthritis. Researchers at Bristol University successfully grew new cartilage from a patient's own stem cells. Experts from Bristol University grew a piece of cartilage using stem cells from the bone marrow of people undergoing hip replacement operations because of the disease. The new technique is expected to overcome problems of transplant rejection because the patient's own cells are used to create the cartilage. Ethical concerns over using human embryos in stem cell research can also be avoided. They hope the technique will allow them to carry out transplants in the future."
Stem cell breakthrough promises arthritis 'cure'
Source: Daily Telegraph
(Filed: 18/12/2005)
Summary:
Scientists are predicting a "cure" for arthritis within the next decade after they successfully grew human cartilage from a patients' own stem cells for the first time. The cells were taken from the bone marrow of pensioners undergoing National Health Service replacement surgery due to the disease. Crucially, the new technique is expected to overcome problems of transplant rejection because the patient's own cells would be used to create the cartilage.
(Filed: 18/12/2005)
Summary:
Scientists are predicting a "cure" for arthritis within the next decade after they successfully grew human cartilage from a patients' own stem cells for the first time. The cells were taken from the bone marrow of pensioners undergoing National Health Service replacement surgery due to the disease. Crucially, the new technique is expected to overcome problems of transplant rejection because the patient's own cells would be used to create the cartilage.
Friday, December 16, 2005
Stem-cell therapies make a comeback
Source: New Scientist
16 December 2005
Summary:
Stem cells that migrate from bone marrow and fuse with cells in other tissues could one day be used to repair cells in people with genetic diseases.
16 December 2005
Summary:
Stem cells that migrate from bone marrow and fuse with cells in other tissues could one day be used to repair cells in people with genetic diseases.
Thursday, December 15, 2005
USC Researchers Track Down The Stem Cells That Create Feathers
Source: University Of Southern California
Date: December 15, 2005
Summary:
The stem cells that produce bird feathers have been visualized and analyzed for the first time, signifying the initial step in a scientific journey that may ultimately shed light on human organ regeneration. Feather stem cells are of interest to scientists because of their profound regenerative abilities.
Date: December 15, 2005
Summary:
The stem cells that produce bird feathers have been visualized and analyzed for the first time, signifying the initial step in a scientific journey that may ultimately shed light on human organ regeneration. Feather stem cells are of interest to scientists because of their profound regenerative abilities.
Engineered Stem Cells Show Promise For Sneaking Drugs Into The Brain
Source: University of Wisconsin-Madison
Date: December 15, 2005
Summary:
Scientists have found a new way to sneak drugs past the blood-brain barrier by engineering and implanting progenitor brain cells derived from stem cells to produce and deliver a critical growth factor that has already shown clinical promise for treating Parkinson's disease. In the journal Gene Therapy, scientists describe experiments that demonstrate that engineered human brain progenitor cells, transplanted into the brains of rats and monkeys, can effectively integrate into the brain and deliver medicine where it is needed.
Date: December 15, 2005
Summary:
Scientists have found a new way to sneak drugs past the blood-brain barrier by engineering and implanting progenitor brain cells derived from stem cells to produce and deliver a critical growth factor that has already shown clinical promise for treating Parkinson's disease. In the journal Gene Therapy, scientists describe experiments that demonstrate that engineered human brain progenitor cells, transplanted into the brains of rats and monkeys, can effectively integrate into the brain and deliver medicine where it is needed.
Adult stem cells 'fusion hope'
Source: BBC News
Published: 2005/12/15 01:11:54 GMT
Summary:
BBC News reports on news findings by US researchers that point to the potentially increase flexibility of adult stem cells:
"US researchers said evidence had shown adult cells could be effectively fused with other cells to work elsewhere. US researchers said evidence had shown adult cells could be effectively fused with other cells to work elsewhere, New Scientist magazine reported."
Published: 2005/12/15 01:11:54 GMT
Summary:
BBC News reports on news findings by US researchers that point to the potentially increase flexibility of adult stem cells:
"US researchers said evidence had shown adult cells could be effectively fused with other cells to work elsewhere. US researchers said evidence had shown adult cells could be effectively fused with other cells to work elsewhere, New Scientist magazine reported."
'Engineered' Stem Cells May Help Treat Parkinson's: They are able to penetrate the brain's blood barrier, researchers report
Source: HealthDay News
Date: December 15, 2005
Summary:
Engineered human progenitor brain stem cells are able to produce and deliver into the brain a growth factor that shows promise in treating Parkinson's disease, say researchers at the University of Wisconsin-Madison.
Date: December 15, 2005
Summary:
Engineered human progenitor brain stem cells are able to produce and deliver into the brain a growth factor that shows promise in treating Parkinson's disease, say researchers at the University of Wisconsin-Madison.
Wednesday, December 14, 2005
OHSU Discovery Sheds Light Into How Stem Cells Become Brain Cells
Source: Oregon Health & Science University
Posted: December 14, 2005
Summary:
Researchers have discovered one key gene that appears to control how stem cells become various kinds of brain cells. The finding has significant implications for the study of Parkinson's disease, brain and spinal cord injury, and other conditions or diseases that might be combated by replacing lost or damaged brain cells.
Posted: December 14, 2005
Summary:
Researchers have discovered one key gene that appears to control how stem cells become various kinds of brain cells. The finding has significant implications for the study of Parkinson's disease, brain and spinal cord injury, and other conditions or diseases that might be combated by replacing lost or damaged brain cells.
Ataxia sufferer's stem cell hope
Source: BBC News
Published: 2005/12/14 12:49:09 GMT
Summary:
A woman thought to be the first person in the world to be undergoing stem cell treatment for a rare neurological condition is travelling to the Netherlands to combat Friedreich's Ataxia. The condition is caused by a faulty gene which affects her balance, co-ordination and speech.
Published: 2005/12/14 12:49:09 GMT
Summary:
A woman thought to be the first person in the world to be undergoing stem cell treatment for a rare neurological condition is travelling to the Netherlands to combat Friedreich's Ataxia. The condition is caused by a faulty gene which affects her balance, co-ordination and speech.
Tuesday, December 13, 2005
Researchers Discover A Protein Responsible For Shaping The Nervous System
Source: University of Toronto
Date: December 13, 2005
Summary:
A team of researchers have discovered a protein that is responsible for shaping the nervous system. The protein guides the nervous system in disposing of the ineffective nerve cells. The protein is from a family of tumour suppressor proteins that is mutated in many human cancers. While the protein is involved in determining which nerve cells die, the research team also suspects that it determines whether nerve cells die when injured or in neurological and neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.
Date: December 13, 2005
Summary:
A team of researchers have discovered a protein that is responsible for shaping the nervous system. The protein guides the nervous system in disposing of the ineffective nerve cells. The protein is from a family of tumour suppressor proteins that is mutated in many human cancers. While the protein is involved in determining which nerve cells die, the research team also suspects that it determines whether nerve cells die when injured or in neurological and neurodegenerative diseases such as Alzheimer's and Parkinson's diseases.
Key Gene In Development Of Connections Between Brain And Spinal Cord Identified
Source: Medical News Today
Posted: 13 December 2005 - 19:00pm (UK)
Summary:
A new study has identified a specific gene that is necessary for the development of connections between the brain and the spinal cord. This research could be critical for future understanding of the development of the human brain and possibly the treatment of spinal cord injuries.
Posted: 13 December 2005 - 19:00pm (UK)
Summary:
A new study has identified a specific gene that is necessary for the development of connections between the brain and the spinal cord. This research could be critical for future understanding of the development of the human brain and possibly the treatment of spinal cord injuries.
U of L achieves 'amazing' find with stem cells: Treatments for diseases could result from work
Source: Courier-Journal
Date: December 13, 2005
Summary:
University of Louisville researchers have coaxed stem cells from adult mice to change into brain, nerve, heart and pancreatic cells — a discovery that could lead to treatments for a host of human diseases and possibly end the national debate over the use of embryonic stem cells.
Date: December 13, 2005
Summary:
University of Louisville researchers have coaxed stem cells from adult mice to change into brain, nerve, heart and pancreatic cells — a discovery that could lead to treatments for a host of human diseases and possibly end the national debate over the use of embryonic stem cells.
In the brains of mice grow the cells of man: Embryonic implants mature into neurons to help fight diseases
Source: San Francisco Chronicle
Date: December 13, 2005
Summary:
Researchers in San Diego have designed mice containing fully functional human nerve cells as a novel way to study and potentially treat neurodegenerative diseases such as Parkinson's and Alzheimer's. The neurons were formed in the brains of mice that had been injected with human embryonic stem cells as 2-week-old embryos.
Date: December 13, 2005
Summary:
Researchers in San Diego have designed mice containing fully functional human nerve cells as a novel way to study and potentially treat neurodegenerative diseases such as Parkinson's and Alzheimer's. The neurons were formed in the brains of mice that had been injected with human embryonic stem cells as 2-week-old embryos.
Human Brain Cells Are Grown In Mice: Success Is Encouraging For Stem Cell Therapies
Source: Washington Post
Date: December 13, 2005
Summary:
By injecting human embryonic stem cells into the brains of fetal mice inside the womb, scientists have created living mice with working human brain cells inside their skulls. The research offers the first proof that human embryonic stem cells can become functional human brain cells inside a living animal.
Date: December 13, 2005
Summary:
By injecting human embryonic stem cells into the brains of fetal mice inside the womb, scientists have created living mice with working human brain cells inside their skulls. The research offers the first proof that human embryonic stem cells can become functional human brain cells inside a living animal.
Monday, December 12, 2005
Mice grow human brain cells after stem cell injections
Source: Associated Press
Date: December 12, 2005
Summary:
Scientists announced Monday that they had created mice with small amounts of human brain cells in an effort to make realistic models of neurological disorders such as Parkinson's disease.
Date: December 12, 2005
Summary:
Scientists announced Monday that they had created mice with small amounts of human brain cells in an effort to make realistic models of neurological disorders such as Parkinson's disease.
Exciting Strides Being Made in Stem Cell Research
Source: American Society of Hematology
December 12, 2005
Summary:
Four studies highlight new information about the potential of stem cells, from determining the type and location of stem cells in bone marrow to controlling the differentiation of cells into desired cell types and determining how well stem cell transplants actually work in treating cancers. Researchers have found for the first time that adult bone marrow contains a distinct population of stem cells that are uniquely responsible for the development of nerve tissue. The findings will help researchers refine their thinking about how the body repairs nerve and brain tissue throughout the life cycle.
December 12, 2005
Summary:
Four studies highlight new information about the potential of stem cells, from determining the type and location of stem cells in bone marrow to controlling the differentiation of cells into desired cell types and determining how well stem cell transplants actually work in treating cancers. Researchers have found for the first time that adult bone marrow contains a distinct population of stem cells that are uniquely responsible for the development of nerve tissue. The findings will help researchers refine their thinking about how the body repairs nerve and brain tissue throughout the life cycle.
Friday, December 09, 2005
How The Neuron Sprouts Its Branches
Source: Duke University Medical Center
Posted: December 9, 2005
Summary:
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors. It will also help researchers better understand brain development in children, as well as aid efforts to restore neuronal connections lost to injury, stroke or neurodegenerative disease, said the researchers.
Posted: December 9, 2005
Summary:
Neurobiologists have gained new insights into how neurons control growth of the intricate tracery of branches called dendrites that enable them to connect with their neighbors. It will also help researchers better understand brain development in children, as well as aid efforts to restore neuronal connections lost to injury, stroke or neurodegenerative disease, said the researchers.
Wednesday, December 07, 2005
UCSF Study Finds Nerve Regeneration Is Possible In Spinal Cord Injuries
Source: University of California - San Francisco
Date: December 7, 2005
Summary:
A team of scientists at UCSF has made a critical discovery that may help in the development of techniques to promote functional recovery after a spinal cord injury. By stimulating nerve cells in laboratory rats at the time of the injury and then again one week later, the scientists were able to increase the growth capacity of nerve cells and to sustain that capacity. Both factors are critical for nerve regeneration.
Date: December 7, 2005
Summary:
A team of scientists at UCSF has made a critical discovery that may help in the development of techniques to promote functional recovery after a spinal cord injury. By stimulating nerve cells in laboratory rats at the time of the injury and then again one week later, the scientists were able to increase the growth capacity of nerve cells and to sustain that capacity. Both factors are critical for nerve regeneration.
Tuesday, December 06, 2005
Stem cell find may lead to prostate cancer cure
Source: Daily Telegraph
Date: 6 December 2005
Summary:
The Daily Telegraph reports on the discovery of a new method of inhibiting prostate cancer stem cells:
"A new way of inhibiting prostate cancer cells has been found that could prevent the disease returning after treatment. The research could also have implications for the treatment of other cancers. The research could also have implications for the treatment of other cancers. Tumour stem cells also occur in breast and colon cancers, as well as in brain tumours."
Date: 6 December 2005
Summary:
The Daily Telegraph reports on the discovery of a new method of inhibiting prostate cancer stem cells:
"A new way of inhibiting prostate cancer cells has been found that could prevent the disease returning after treatment. The research could also have implications for the treatment of other cancers. The research could also have implications for the treatment of other cancers. Tumour stem cells also occur in breast and colon cancers, as well as in brain tumours."
Thursday, December 01, 2005
Hair Follicle Stem Cells Contribute To Wound Healing
Source: University of Pennsylvania School of Medicine
Date: December 1, 2005
Summary:
Hair follicle stem cells are important contributors to the wound-healing process, according to new research by investigators at the University of Pennsylvania School of Medicine. Using an animal model, the researchers discovered that stem cells in the hair follicle are enlisted to help heal wounds in the skin. This finding, published online in Nature Medicine last week, may suggest a therapeutic target for the development of drugs to encourage and promote wound healing.
Date: December 1, 2005
Summary:
Hair follicle stem cells are important contributors to the wound-healing process, according to new research by investigators at the University of Pennsylvania School of Medicine. Using an animal model, the researchers discovered that stem cells in the hair follicle are enlisted to help heal wounds in the skin. This finding, published online in Nature Medicine last week, may suggest a therapeutic target for the development of drugs to encourage and promote wound healing.
Cord Blood Stem Cells Key To Saving Lives: Doctors Hope To Increase Cord Blood Stem Cell Donors
Source: WRC-TV4, Washington, D.C.
POSTED: 6:18 pm EST November 30, 2005
UPDATED: 6:24 am EST December 1, 2005
Summary:
WRC-TV4, Washington, D.C. reports on new cord blood stem cell research and emphasize the importance of saving umbilical cords and the need for cord blood donors:
FAIRFAX, Va. -- Doctors hope to increase the number of donations of cord blood stem cells. The cells are a proven lifesaver that get thrown away in hospitals everyday. Cord blood stem cells are different than the controversial embryonic stem cells. They come from the umbilical cords of newborn babies -- a material that's usually discarded even though they're already proven lifesavers.
POSTED: 6:18 pm EST November 30, 2005
UPDATED: 6:24 am EST December 1, 2005
Summary:
WRC-TV4, Washington, D.C. reports on new cord blood stem cell research and emphasize the importance of saving umbilical cords and the need for cord blood donors:
FAIRFAX, Va. -- Doctors hope to increase the number of donations of cord blood stem cells. The cells are a proven lifesaver that get thrown away in hospitals everyday. Cord blood stem cells are different than the controversial embryonic stem cells. They come from the umbilical cords of newborn babies -- a material that's usually discarded even though they're already proven lifesavers.
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