Source: Forsyth Institute
Date: February 28, 2007
Summary:
Scientists at Forsyth may have moved one step closer to regenerating human spinal cord tissue by artificially inducing a frog tadpole to re-grow its tail at a stage in its development when it is normally impossible. Using a variety of methods including a kind of gene therapy, the scientists altered the electrical properties of cells thus inducing regeneration. This discovery may provide clues about how bioelectricity can be used to help humans regenerate.
Wednesday, February 28, 2007
Stem cells may have role in cancer relapse
Source: USA Today
Date: February 28, 2007
Summary:
New research from Johns Hopkins University suggests that a small group of especially hardy cells, called cancer stem cells, could explain why tumors grow back, sometimes years later, despite even the harshest therapies. These relapses often prove fatal, taking the lives of patients who appeared cancer free.
Date: February 28, 2007
Summary:
New research from Johns Hopkins University suggests that a small group of especially hardy cells, called cancer stem cells, could explain why tumors grow back, sometimes years later, despite even the harshest therapies. These relapses often prove fatal, taking the lives of patients who appeared cancer free.
Researchers grow heart tissue from stem cells
Source: The Post-Bulletin - Rochester, MN
Posted: February 28, 2007 10:20:43 AM CST
Summary:
According to a study published in the February issue of the Journal of Experimental Medicine, researchers at the Mayo Clinic discovered a way to grow new heart tissue in mice using embryonic stem cells without creating cancerous tumors for the first time, successfully fixing heart attack damage.
Posted: February 28, 2007 10:20:43 AM CST
Summary:
According to a study published in the February issue of the Journal of Experimental Medicine, researchers at the Mayo Clinic discovered a way to grow new heart tissue in mice using embryonic stem cells without creating cancerous tumors for the first time, successfully fixing heart attack damage.
Tuesday, February 27, 2007
Sox17 required for transformation of embryonic stem cell to heart muscle cell
Source: Baylor College of Medicine
Date: February 27, 2007
Summary:
An important choreographer of the complicated dance of signals, enzymes and proteins that takes embryonic stem cells through the steps to becoming a beating heart muscle cell is the gene Sox17, said researchers from Baylor College of Medicine in a report in the current issue of the Proceedings of the National Academy of Sciences.
Date: February 27, 2007
Summary:
An important choreographer of the complicated dance of signals, enzymes and proteins that takes embryonic stem cells through the steps to becoming a beating heart muscle cell is the gene Sox17, said researchers from Baylor College of Medicine in a report in the current issue of the Proceedings of the National Academy of Sciences.
Mayo Clinic Researchers Safely Regenerate Failing Mouse Hearts with Programmed Embryonic Stem Cells
Source: Mayo Clinic
Date: February 27, 2007
Summary:
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor -- which, so far, has impeded successful translation into practice of embryonic stem cell research.
Date: February 27, 2007
Summary:
Mayo Clinic researchers have safely transplanted cardiac preprogrammed embryonic stem cells into diseased hearts of mice successfully regenerating infarcted heart muscle without precipitating the growth of a cancerous tumor -- which, so far, has impeded successful translation into practice of embryonic stem cell research.
MIT bioengineer advances survival, promise of adult stem cells
Source: Massachusetts Institute of Technology
Date: February 27, 2007
Summary:
MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. Griffith is the senior author of a recent study showing that when presented in the right physical context, certain growth factors encourage the survival and proliferation of bone marrow mesenchymal stem cells grown outside of the body.
Date: February 27, 2007
Summary:
MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. Griffith is the senior author of a recent study showing that when presented in the right physical context, certain growth factors encourage the survival and proliferation of bone marrow mesenchymal stem cells grown outside of the body.
UT Scientists Develop Promising New Procedure To Differentiate Human Embryonic Stem Cells
Source: University of Texas Health Science Center at Houston
Date: February 26, 2007
Summary:
Molecular scientists at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) – which is part of the University of Texas Health Science Center at Houston – have developed a new procedure for the differentiation of human embryonic stem cells, with which they have created the first transplantable source of lung epithelial cells.
Date: February 26, 2007
Summary:
Molecular scientists at the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM) – which is part of the University of Texas Health Science Center at Houston – have developed a new procedure for the differentiation of human embryonic stem cells, with which they have created the first transplantable source of lung epithelial cells.
Saturday, February 24, 2007
Hormonal Surge During Pregnancy Repairs Faulty Brain Signaling
Source: Scientific American
Date: February 24, 2007
Scientific Americanreports on a new finding that could have implications for treating Multiple Sclerosis:
"In what could give hope to the 2.5 million sufferers of multiple sclerosis (MS) worldwide, a new study reports that the hormone prolactin, the levels of which spike during pregnancy, mended nerve damage in mice."
Date: February 24, 2007
Scientific Americanreports on a new finding that could have implications for treating Multiple Sclerosis:
"In what could give hope to the 2.5 million sufferers of multiple sclerosis (MS) worldwide, a new study reports that the hormone prolactin, the levels of which spike during pregnancy, mended nerve damage in mice."
Friday, February 23, 2007
Bringing The Curative Power Of Stem Cell Transplants To More Patients - How A New Mouse Model Shows The Way
Source: H. Lee Moffitt Cancer Center & Research Institute
Date: 23 Feb 2007 - 12:00 PST
Summary:
A Leukemia and Lymphoma Society-funded researcher, William Kerr Ph.D. of the H. Lee Moffitt Cancer Center & Research Institute, is working to bring this potentially curative option to more blood cancer patients. His latest research breakthroughs will be published this month in the Journal of Immunology.
Date: 23 Feb 2007 - 12:00 PST
Summary:
A Leukemia and Lymphoma Society-funded researcher, William Kerr Ph.D. of the H. Lee Moffitt Cancer Center & Research Institute, is working to bring this potentially curative option to more blood cancer patients. His latest research breakthroughs will be published this month in the Journal of Immunology.
Thursday, February 22, 2007
Breakthrough suggests hope for neurodegenerative diseases
Source: Pharmaceutical Business Review
Date: February 22, 2007
Summary:
Scientists from Universite Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor Francois Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson's disease.
Date: February 22, 2007
Summary:
Scientists from Universite Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor Francois Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson's disease.
How stem cells are regulated
Source: University of Copenhagen
Date: February 22, 2007
Summary:
Researchers from Biotech Research & Innovation Centre (BRIC) at University of Copenhagen have identified a new group of proteins that regulate the function of stem cells. The results are published in the new issue of Cell.
Date: February 22, 2007
Summary:
Researchers from Biotech Research & Innovation Centre (BRIC) at University of Copenhagen have identified a new group of proteins that regulate the function of stem cells. The results are published in the new issue of Cell.
Stem cell research sheds light on organ regeneration
Source: Harvard University Gazette
Date: February 22, 2007
Summary:
A new study by Harvard Stem Cell Institute co-director Doug Melton and colleagues published in today's issue of the journal Nature helps to explain the variation both in organ regenerative capacity and in organ size determination as well. The findings also underscore the value of embryonic stem cells as tools to study normal development.
Date: February 22, 2007
Summary:
A new study by Harvard Stem Cell Institute co-director Doug Melton and colleagues published in today's issue of the journal Nature helps to explain the variation both in organ regenerative capacity and in organ size determination as well. The findings also underscore the value of embryonic stem cells as tools to study normal development.
Liposuctioned fat stem cells to repair bodies
Source: European Science Foundation
Date: February 22, 2007
Summary:
Expanding waistlines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body. A team led by Philippe Collas at the University of Oslo in Norway has identified certain chemical marks that allow him to predict which, among the hundreds of millions of stem cells in liposuctioned fat, are best at regenerating tissue.
Date: February 22, 2007
Summary:
Expanding waistlines, unsightly bulges: people will gladly remove excess body fat to improve their looks. But unwanted fat also contains stem cells with the potential to repair defects and heal injuries in the body. A team led by Philippe Collas at the University of Oslo in Norway has identified certain chemical marks that allow him to predict which, among the hundreds of millions of stem cells in liposuctioned fat, are best at regenerating tissue.
Scientists Produce Neurons From Human Skin
Source: Université Laval
Date: February 22, 2007
Summary:
Scientists from Université Laval’s Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor François Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson’s disease. Berthod and his team described the method used to produce these neurons in a recent issue of the Journal of Cellular Physiology.
Date: February 22, 2007
Summary:
Scientists from Université Laval’s Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor François Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson’s disease. Berthod and his team described the method used to produce these neurons in a recent issue of the Journal of Cellular Physiology.
Regrowing Teeth
Source: Technology Review
Date: February 22, 2007
Summary:
Japanese researchers recently reported in Nature Methods they had successfully regrown a tooth from cells extracted from mouse embryos. The researchers were able to transplant the tooth into an adult mouse, and the tooth bud continued to grow to full size. However, researchers caution in that it is unclear whether the technique will be effective for re-growing teeth in humans, as the embryonic stem cells used by the researchers are difficult to obtain in large amounts and could be rejected as a foreign substance by a patient's immune system when they are transplanted in to the patient.
Date: February 22, 2007
Summary:
Japanese researchers recently reported in Nature Methods they had successfully regrown a tooth from cells extracted from mouse embryos. The researchers were able to transplant the tooth into an adult mouse, and the tooth bud continued to grow to full size. However, researchers caution in that it is unclear whether the technique will be effective for re-growing teeth in humans, as the embryonic stem cells used by the researchers are difficult to obtain in large amounts and could be rejected as a foreign substance by a patient's immune system when they are transplanted in to the patient.
Wednesday, February 21, 2007
H. Lee Moffitt Researchers to Discover Potential Targets to Reduce Risk of Stem Cell Transplants
Source: Leukemia & Lymphoma Society
Date: February 21, 2007
Summary:
Researchers at H. Lee Moffitt Comprehensive Cancer Center in Tampa, led by William Kerr Ph.D., and funded by The Leukemia & Lymphoma Society, have discovered that the SHIP gene plays a critical role in graft vs. host disease (GvHD), in which a donor's immune cells (the "graft") attack a stem cell transplant patient's healthy tissue (the "host") as well as cancer cells. By using genetically engineered mice, the researchers have shown that inactivating the SHIP gene for just one week protects transplant recipients from acute GvHD. This protection is seen even when the graft contains extra immune cells to help the graft "take" or when the graft cells are completely mismatched to the recipient. The findings will be published in the March 1st issue of the "Journal of Immunology."
Date: February 21, 2007
Summary:
Researchers at H. Lee Moffitt Comprehensive Cancer Center in Tampa, led by William Kerr Ph.D., and funded by The Leukemia & Lymphoma Society, have discovered that the SHIP gene plays a critical role in graft vs. host disease (GvHD), in which a donor's immune cells (the "graft") attack a stem cell transplant patient's healthy tissue (the "host") as well as cancer cells. By using genetically engineered mice, the researchers have shown that inactivating the SHIP gene for just one week protects transplant recipients from acute GvHD. This protection is seen even when the graft contains extra immune cells to help the graft "take" or when the graft cells are completely mismatched to the recipient. The findings will be published in the March 1st issue of the "Journal of Immunology."
Tuesday, February 20, 2007
Pregnancy Hormone Key To Repairing Nerve Cell Damage - MS Society Of Canada
Source: Multiple Sclerosis Society of Canada
Date: February 20, 2007
Summary:
The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that a pregnancy-related hormone is responsible for rebuilding the protective coating around nerve cells.
Date: February 20, 2007
Summary:
The mystery of why multiple sclerosis (MS) tends to go into remission while women are pregnant may be the secret to overcoming the devastating neurodegenerative disease, according to University of Calgary researchers who have shown that a pregnancy-related hormone is responsible for rebuilding the protective coating around nerve cells.
Pregnancy hormone key to repairing nerve cell damage
Source: University of Calgary
Date: February 20, 2007
Summary:
In paper to be published in the February 21 issue of The Journal of Neuroscience, a team of researchers from the University of Calgary Faculty of Medicine reports that a study conducted on mice found that the hormone prolactin encourages the spontaneous production of myelin, the fatty substance that coats nerve cells and plays a critical role in transmitting messages in the central nervous system.
Date: February 20, 2007
Summary:
In paper to be published in the February 21 issue of The Journal of Neuroscience, a team of researchers from the University of Calgary Faculty of Medicine reports that a study conducted on mice found that the hormone prolactin encourages the spontaneous production of myelin, the fatty substance that coats nerve cells and plays a critical role in transmitting messages in the central nervous system.
Are Scientists Making Progress In Being Able To Regenerate Bone Tissue?
Source: Public Library of Science
Date: February 20, 2007
Summary:
In an article in PLoS Medicine, Gert Meijer (University Medical Centre Utrecht, The Netherlands) and colleagues discuss what kind of progress there has been in restoring the function of diseased or damaged bone by bone tissue regeneration.
Date: February 20, 2007
Summary:
In an article in PLoS Medicine, Gert Meijer (University Medical Centre Utrecht, The Netherlands) and colleagues discuss what kind of progress there has been in restoring the function of diseased or damaged bone by bone tissue regeneration.
Tech Could End Deafness
Source: Wired News
Posted: February 20, 2007 10:30 AM PST
Summary:
The science of hearing is advancing to a point where new techniques, such as combining stem-cell transplants with the "recharging" of cells that power an amplifier in the ear, may enable patients to regain their hearing through manipulation of their own biology. A Stanford University professor who discovered stem cells in the inner ear, believes they can be used to cure deafness in mice within five years.
Posted: February 20, 2007 10:30 AM PST
Summary:
The science of hearing is advancing to a point where new techniques, such as combining stem-cell transplants with the "recharging" of cells that power an amplifier in the ear, may enable patients to regain their hearing through manipulation of their own biology. A Stanford University professor who discovered stem cells in the inner ear, believes they can be used to cure deafness in mice within five years.
Cancer Is A Stem Cell Issue
Source: European Science Foundation
Date: February 19, 2007
Summary:
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. Mounting evidence implicates a clutch of rogue stem cells brandishing ‘epigenetic’ marks as the main culprits in cancer. Wiping out tumours for good, some biologists believe, depends on uprooting these wayward stem cells.
Date: February 19, 2007
Summary:
There is an urgent reason to study stem cells: stem cells are at the heart of some, if not all, cancers. Mounting evidence implicates a clutch of rogue stem cells brandishing ‘epigenetic’ marks as the main culprits in cancer. Wiping out tumours for good, some biologists believe, depends on uprooting these wayward stem cells.
Monday, February 19, 2007
Adult stem cell trial sees success at IU
Source: WTHR 13 - TV, Indianapolis, IN
Posted: February 19, 2007 02:04 PM
Summary:
Researchers at Indiana University conducted a clinical trial in an attempt to save limbs from amputation as a result of peripheral arterial disease (PAD), a circulatory condition in which narrowed arteries reduce the blood flow to limbs, with a patient's own stem cells. Researchers removed bone marrow from patients' hips, isolated adult stem cells in the lab and injected a patient's own stem cells back into the leg. Patients who participated in the trial reported improved circulation and reduced pain. The success of the trials is prompting researchers to expand stem cell trials for PAD and add studies on stroke and heart disease.
Posted: February 19, 2007 02:04 PM
Summary:
Researchers at Indiana University conducted a clinical trial in an attempt to save limbs from amputation as a result of peripheral arterial disease (PAD), a circulatory condition in which narrowed arteries reduce the blood flow to limbs, with a patient's own stem cells. Researchers removed bone marrow from patients' hips, isolated adult stem cells in the lab and injected a patient's own stem cells back into the leg. Patients who participated in the trial reported improved circulation and reduced pain. The success of the trials is prompting researchers to expand stem cell trials for PAD and add studies on stroke and heart disease.
Science Finds New Ways to Regrow Fingers
Source: Associated Press
Date: February 19, 2007
Summary:
Researchers are investigating ways to regrow fingers — and someday, even limbs by studying how some animals regrow body parts. In studying the mice and salamanders, scientists will examine the role of cells, genes and biochemical signals in order to possibly translate their findings into applications for human limb regeneration.
Date: February 19, 2007
Summary:
Researchers are investigating ways to regrow fingers — and someday, even limbs by studying how some animals regrow body parts. In studying the mice and salamanders, scientists will examine the role of cells, genes and biochemical signals in order to possibly translate their findings into applications for human limb regeneration.
New Hope For Regenerative Medicine: Hematopoietic Reconstitution With Uniparental Stem Cells
Source: Cold Spring Harbor Laboratory
Date: February 19, 2007
Summary:
Researchers at Cold Spring Harbor Laboratory reported on their success in using uniparental embryonic stem cells to replace blood stem cells in adult mice. Uniparental embryonic stem cells are an appealing alternative source of patient-derived embryonic stem cells, as they have several advantages over embryonic stem cell lines generated by somatic cell nuclear transfer (also known as therapeutic cloning).
Date: February 19, 2007
Summary:
Researchers at Cold Spring Harbor Laboratory reported on their success in using uniparental embryonic stem cells to replace blood stem cells in adult mice. Uniparental embryonic stem cells are an appealing alternative source of patient-derived embryonic stem cells, as they have several advantages over embryonic stem cell lines generated by somatic cell nuclear transfer (also known as therapeutic cloning).
One-parent embryos: A step ahead in stem cells
Source: Philadelphia Inquirer
Date: February 19, 2007
Summary:
In studies with mice, University of Pennsylvania researchers have created embryos using genetic material from only one parent - either a mother or a father, terminating the development of the embryo, but after it had reached the stage where it contained embryonic stem cells. The embryonic stem cells were used to restore the blood systems of adult mice whose own blood cells had been destroyed by radiation.
Date: February 19, 2007
Summary:
In studies with mice, University of Pennsylvania researchers have created embryos using genetic material from only one parent - either a mother or a father, terminating the development of the embryo, but after it had reached the stage where it contained embryonic stem cells. The embryonic stem cells were used to restore the blood systems of adult mice whose own blood cells had been destroyed by radiation.
Sunday, February 18, 2007
Custom-made Cancer Cell Attacks
Source: Natural Sciences and Engineering Research Council
Date: February 19, 2007
Summary:
Researchers are taking vast amounts of radioactive material and separating the particular atoms they need for therapy in order to create cancer treatment that are tailored to the cells in a patient's body, with each person receiving a unique treatment program. Bearing that principle in mind, researchers can make custom types of radioactive chemicals -- or radioisotopes -- that will attack cancer cells in a more efficient way than current cancer treatments.
Date: February 19, 2007
Summary:
Researchers are taking vast amounts of radioactive material and separating the particular atoms they need for therapy in order to create cancer treatment that are tailored to the cells in a patient's body, with each person receiving a unique treatment program. Bearing that principle in mind, researchers can make custom types of radioactive chemicals -- or radioisotopes -- that will attack cancer cells in a more efficient way than current cancer treatments.
Japanese scientists grow teeth from single cells
Source: Reuters
Posted: February 18, 2007 9:10PM EST
Summary:
Japanese researchers reported they had grown normal-looking teeth from single cells in lab dishes, and transplanted them into mice. After growing them, they found their structures had developed into compounds that make teeth, including dentin, enamel, dental pulp, blood vessels, and periodontal ligaments.
Posted: February 18, 2007 9:10PM EST
Summary:
Japanese researchers reported they had grown normal-looking teeth from single cells in lab dishes, and transplanted them into mice. After growing them, they found their structures had developed into compounds that make teeth, including dentin, enamel, dental pulp, blood vessels, and periodontal ligaments.
Bioengineering helps toothless mice smile again
Source: Agence France Presse
Posted: February 18, 2007 2:08 PM ET
Summary:
In a world first, Japanese researchers reported Sunday they had successfully replaced natural teeth in mice with teeth that were created in a lab dish from single blood and skin cells.
Posted: February 18, 2007 2:08 PM ET
Summary:
In a world first, Japanese researchers reported Sunday they had successfully replaced natural teeth in mice with teeth that were created in a lab dish from single blood and skin cells.
Loud music and noisy world take toll on hearing
Source: Associated Press
Date: February 18, 2007
Summary:
Damage to the inner cells cannot be repaired and causes deafness. Now researchers at Stanford University have isolated ear stem cells in a laboratory and coaxed them to grow into cells that resembled hair cells that have potential to restore lost hearing.
Date: February 18, 2007
Summary:
Damage to the inner cells cannot be repaired and causes deafness. Now researchers at Stanford University have isolated ear stem cells in a laboratory and coaxed them to grow into cells that resembled hair cells that have potential to restore lost hearing.
Stem cell transplants explored at Stanford as a possible treatment for hearing loss
Source: Stanford University Medical Center
Date: February 17, 2007
Summary:
Researchers at Stanford University are working to develop a variety of possible cures for deafness, focusing on two paths: drug therapy -- which could be as simple as an application of ear drops - and stem cell transplantation into the inner ear to remedy hearing loss.
Date: February 17, 2007
Summary:
Researchers at Stanford University are working to develop a variety of possible cures for deafness, focusing on two paths: drug therapy -- which could be as simple as an application of ear drops - and stem cell transplantation into the inner ear to remedy hearing loss.
Saturday, February 17, 2007
Movement of new cells pave way for brain research
Source: University of Auckland
Date: February 16, 2007
Summary:
Scientists from The University of Auckland, alongside colleagues in Sweden, have discovered how new brain stem cells migrate throughout the brain, a finding which opens the way for new treatments of neurological diseases such as Alzheimer’s, Parkinson’s and Huntington’s.
Date: February 16, 2007
Summary:
Scientists from The University of Auckland, alongside colleagues in Sweden, have discovered how new brain stem cells migrate throughout the brain, a finding which opens the way for new treatments of neurological diseases such as Alzheimer’s, Parkinson’s and Huntington’s.
Friday, February 16, 2007
Marker That Identifies Energy-producing Centers In Nerve Cells Can Help Track Metabolic Changes Related To Aging And Diseases
Source: University of Maryland Medical Center
Date: February 16, 2007
Summary:
A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system. This fluorescent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases.
Date: February 16, 2007
Summary:
A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system. This fluorescent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases.
Brain creates 'new' nerve cells
Source: BBC News
Posted: 16 February 2007, 00:01 GMT
Summary:
New Zealand and Swedish researchers have discovered a type of brain cell that continuously regenerates in humans. Experts said the findings, published in Science, opened up the potential for research into repairing brains in degenerative conditions such as Alzheimer's disease.
Posted: 16 February 2007, 00:01 GMT
Summary:
New Zealand and Swedish researchers have discovered a type of brain cell that continuously regenerates in humans. Experts said the findings, published in Science, opened up the potential for research into repairing brains in degenerative conditions such as Alzheimer's disease.
Thursday, February 15, 2007
Human adult stem cells regenerate muscle
Source: United Press International
Date: February 15, 2007
Summary:
Italian scientists have found human adult stem cells taken from blood vessels can regenerate muscle in a mouse model of muscular dystrophy.
Date: February 15, 2007
Summary:
Italian scientists have found human adult stem cells taken from blood vessels can regenerate muscle in a mouse model of muscular dystrophy.
Researchers Track Path of Humans' New Brain Cells
Source: NPR - All Things Considered
Date: February 15, 2007
Summary:
A team of New Zealand researchers seems to have discovered the source and mapped the path of adult brain cells. Next, the researchers need to find a way to use this pathway to get new brain cells to places that need repair.
Date: February 15, 2007
Summary:
A team of New Zealand researchers seems to have discovered the source and mapped the path of adult brain cells. Next, the researchers need to find a way to use this pathway to get new brain cells to places that need repair.
Brain cell regeneration sniffed out in adult humans
Source: NewScientist.com news service
Posted: 19:00 15 February 2007
Summary:
The presence of newly generated cells in a brain region responsible for processing smells has been revealed in middle-aged and elderly people. The finding adds to mounting evidence that brain cell regeneration continues throughout adulthood in humans.
Posted: 19:00 15 February 2007
Summary:
The presence of newly generated cells in a brain region responsible for processing smells has been revealed in middle-aged and elderly people. The finding adds to mounting evidence that brain cell regeneration continues throughout adulthood in humans.
Human brain can regrow cells, study shows
Source: Reuters
Posted: February 15, 2007 2:27 PM EST
Summary:
New Zealand and Swedish researchers have demonstrated that the human brain can produce new brain cells, in a study that may lead more effective treatments for brain damage and disease. The researchers say the finding provides another area of study that could reveal ways to repair human brains that are damaged from injury or diseases, and emphasizes the importance of animal research in guiding biomedical research in humans.
Posted: February 15, 2007 2:27 PM EST
Summary:
New Zealand and Swedish researchers have demonstrated that the human brain can produce new brain cells, in a study that may lead more effective treatments for brain damage and disease. The researchers say the finding provides another area of study that could reveal ways to repair human brains that are damaged from injury or diseases, and emphasizes the importance of animal research in guiding biomedical research in humans.
Stem Cells Determine Their Daughters’ Fate
Source: Carnegie Institution
Date: February 15, 2007
Summary:
From roundworm to human, most cells in an animal's body ultimately come from stem cells. When one of these versatile, unspecialized cells divides, the resulting "daughter" cell receives instructions to differentiate into a specific cell type. In some cases this signal comes from other cells. But now, for the first time, researchers at the Carnegie Institution's Department of Embryology have found a type of stem cell that directly determines the fate of its daughters.
Date: February 15, 2007
Summary:
From roundworm to human, most cells in an animal's body ultimately come from stem cells. When one of these versatile, unspecialized cells divides, the resulting "daughter" cell receives instructions to differentiate into a specific cell type. In some cases this signal comes from other cells. But now, for the first time, researchers at the Carnegie Institution's Department of Embryology have found a type of stem cell that directly determines the fate of its daughters.
Researchers discover 'sticky' proteins fuse adult stem cells to cardiac muscle, repairing hearts
Source: University of Texas M. D. Anderson Cancer Center
Date: February 15, 2007
Summary:
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. Now, in animal experiments, researchers at The University of Texas M. D. Anderson Cancer Center have deconstructed the process, describing how the stem cells fuse with heart muscle cells to create new cells that repopulate the ailing organ.
Date: February 15, 2007
Summary:
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. Now, in animal experiments, researchers at The University of Texas M. D. Anderson Cancer Center have deconstructed the process, describing how the stem cells fuse with heart muscle cells to create new cells that repopulate the ailing organ.
Harnessing the brain’s plasticity key to treating neurological damage
Source: University of California - San Francisco
Date: February 15, 2007
Summary:
Neuroscientists and engineers are working on the development of “smart” neural prostheses to treat complex neurological impairments. The devices are intended to restore function, through electrical stimulation, to damaged motor neural circuits – the long, slender fibers that conduct neurochemical messages between nerve cells in the brain and spinal cord.
Date: February 15, 2007
Summary:
Neuroscientists and engineers are working on the development of “smart” neural prostheses to treat complex neurological impairments. The devices are intended to restore function, through electrical stimulation, to damaged motor neural circuits – the long, slender fibers that conduct neurochemical messages between nerve cells in the brain and spinal cord.
Penn Researchers Replace Organ in Adult Mice Using "Single-Parent" Stem Cells From Sperm or Egg Alone
Source: University of Pennsylvania
Date: February 15, 2007
Summary:
Researchers at the University of Pennsylvania School of Veterinary Medicine have derived uniparental embryonic stem cells - created from a single donor's eggs or two sperm - and, for the first time, successfully used them to repopulate a damaged organ with healthy cells in adult mice. Their findings demonstrate that single-parent stem cells can proliferate normally in an adult organ and could provide a less controversial alternative to the therapeutic cloning of embryonic stem cells.
Date: February 15, 2007
Summary:
Researchers at the University of Pennsylvania School of Veterinary Medicine have derived uniparental embryonic stem cells - created from a single donor's eggs or two sperm - and, for the first time, successfully used them to repopulate a damaged organ with healthy cells in adult mice. Their findings demonstrate that single-parent stem cells can proliferate normally in an adult organ and could provide a less controversial alternative to the therapeutic cloning of embryonic stem cells.
Wednesday, February 14, 2007
BrainStorm starts preclinical Parkinson's trial
Source: Pharmaceutical Business Review
Date: February 14, 2007
Summary:
BrainStorm Cell Therapeutics has begun a safety trial using its adult stem cell technology in an animal model of Parkinson's disease. The company's adult stem cell technology has proven effective in animal models of Parkinson's disease in previous preclinical trials.
Date: February 14, 2007
Summary:
BrainStorm Cell Therapeutics has begun a safety trial using its adult stem cell technology in an animal model of Parkinson's disease. The company's adult stem cell technology has proven effective in animal models of Parkinson's disease in previous preclinical trials.
Gene Discovery Boosts Brain Cancer Research
Source: HealthDay News
Date: February 14, 2007
Summary:
Researchers have discovered that a gene that triggers the growth of stem cells during early brain development is also key to the growth of deadly adult brain tumors called gliomas.
Date: February 14, 2007
Summary:
Researchers have discovered that a gene that triggers the growth of stem cells during early brain development is also key to the growth of deadly adult brain tumors called gliomas.
New Protein Super-family Discovered With Critical Functions For Animal Life
Source: Public Library of Science
Date: February 14, 2007
Summary:
Biologists have discovered a new super-family of developmental proteins that are critical for cell growth and differentiation and whose further study is expected to benefit research on cancer and the nerve-cell repair.
Date: February 14, 2007
Summary:
Biologists have discovered a new super-family of developmental proteins that are critical for cell growth and differentiation and whose further study is expected to benefit research on cancer and the nerve-cell repair.
'Gateway' gene discovered for brain cancer
Source: Cell Press
Date: February 14, 2007
Summary:
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma. In experiments on mice with such gliomas, they showed that knocking out the function of a particular regulatory protein, Olig2, almost completely eliminated tumor formation.
Date: February 14, 2007
Summary:
Researchers have discovered that the same genetic regulator that triggers growth of stem cells during brain development also plays a central role in the development of the lethal brain cancer malignant glioma. In experiments on mice with such gliomas, they showed that knocking out the function of a particular regulatory protein, Olig2, almost completely eliminated tumor formation.
BrainStorm Cell Therapeutics Initiates Stem Cell Safety Study in Primates for Parkinson’s Disease
Source: BrainStorm Cell Therapeutics
Posted: February 14, 2007 08:30 AM EST
Summary:
BrainStorm Cell Therapeutics, a leader in Adult Stem Cell Research, announced today that it has initiated a safety trial using an animal model of Parkinson’s disease in primates.
Posted: February 14, 2007 08:30 AM EST
Summary:
BrainStorm Cell Therapeutics, a leader in Adult Stem Cell Research, announced today that it has initiated a safety trial using an animal model of Parkinson’s disease in primates.
Tuesday, February 13, 2007
Mice cloned from skin stem cells
Source: CBC News
Date: February 13, 2007 | 11:02 AM ET
Summary:
CBC News Reports: "U.S. researchers said they have cloned mice using stem cells obtained from the rodents' skin, a new technique that could help researchers sidestep the ethical debates over embryonic stem-cell use." Research claim it will enable the development of adult stem cells with traits similar to embryonic stem cells, possibly leading to custom-made treatments for patients that avoid the risk of cells being rejected by the patient's immune system.
Date: February 13, 2007 | 11:02 AM ET
Summary:
CBC News Reports: "U.S. researchers said they have cloned mice using stem cells obtained from the rodents' skin, a new technique that could help researchers sidestep the ethical debates over embryonic stem-cell use." Research claim it will enable the development of adult stem cells with traits similar to embryonic stem cells, possibly leading to custom-made treatments for patients that avoid the risk of cells being rejected by the patient's immune system.
Regenerating fish holds key to muscle growth, researchers say
Source: Canadian Broadcasting Corporation (CBC) - Saskatchewan, Canada
Posted: February 13, 2007 12:03 PM ET
Summary:
The zebrafish, a tropical fish from the minnow family, is a tiny fish with the ability to grow new muscles may hold the cure to a number of degenerative diseases, such as muscular dystrophy and atrophy, according to Australian researchers.
Posted: February 13, 2007 12:03 PM ET
Summary:
The zebrafish, a tropical fish from the minnow family, is a tiny fish with the ability to grow new muscles may hold the cure to a number of degenerative diseases, such as muscular dystrophy and atrophy, according to Australian researchers.
Neuralstem Inc. Cells Survive and Become Neurons in Rats With Spinal Injuries, Study Reports
Source: NeuralStem Inc.
Date: February 13, 2007
Summary:
Human neural stem cells (hNSCs) transplanted into rats with spinal cord damage turned into neurons and made extensive synaptic contact with damaged host motor neurons, a paper published today in PLoS MEDICINE (http://medicine.plosjournals.org) reported. The study, utilizing cells developed by Neuralstem, Inc. (OTC Bulletin Board: NRLS), and conducted at The Johns Hopkins Medical Institutions, led researchers to conclude that the restoration of spinal cord circuitry may be more realistic than previously thought.
Date: February 13, 2007
Summary:
Human neural stem cells (hNSCs) transplanted into rats with spinal cord damage turned into neurons and made extensive synaptic contact with damaged host motor neurons, a paper published today in PLoS MEDICINE (http://medicine.plosjournals.org) reported. The study, utilizing cells developed by Neuralstem, Inc. (OTC Bulletin Board: NRLS), and conducted at The Johns Hopkins Medical Institutions, led researchers to conclude that the restoration of spinal cord circuitry may be more realistic than previously thought.
HUMAN STEM CELL TRANSPLANTS MATURE INTO NEURONS AND MAKE CONTACTS IN RAT SPINAL CORD
Source: Johns Hopkins Medical Institutions
Date: February 13, 2007
Summary:
U.S. scientists say they have disproved the long-held theory that the spinal cord is incapable of repairing itself. The Johns Hopkins University researchers say human nerve stem cells they transplanted into damaged spinal cords of rats have survived, grown and in some cases connected with the rats' own spinal cord cells, overturning the long-held notion that spinal cords won’t allow nerve repair.
Date: February 13, 2007
Summary:
U.S. scientists say they have disproved the long-held theory that the spinal cord is incapable of repairing itself. The Johns Hopkins University researchers say human nerve stem cells they transplanted into damaged spinal cords of rats have survived, grown and in some cases connected with the rats' own spinal cord cells, overturning the long-held notion that spinal cords won’t allow nerve repair.
Monday, February 12, 2007
Scientists clone mice from adult skin stem cells
Source: Rockefeller University
Date: February 12, 2007
Summary;
Researchers at Rockefeller University and Howard Hughes Medical Institute have cloned mice using adult stem cells taken from the rodents' skin for the first time, according to a study that suggests this type of versatile cell can improve the success rate of this notoriously difficult procedure, called nuclear transfer.
Date: February 12, 2007
Summary;
Researchers at Rockefeller University and Howard Hughes Medical Institute have cloned mice using adult stem cells taken from the rodents' skin for the first time, according to a study that suggests this type of versatile cell can improve the success rate of this notoriously difficult procedure, called nuclear transfer.
Stem cells used to boost breasts
Source: BBC News
Posted: 12 February 2007, 17:35 GMT
Summary:
Scientists in Japan claim to be able to increase the size of a woman's breasts by enriching fat from the stomach or thigh fat with stem cells before transplanting it into patients. It is hoped the method could be a more natural-looking alternative to artificial implants filled with salt water or silicone.
Posted: 12 February 2007, 17:35 GMT
Summary:
Scientists in Japan claim to be able to increase the size of a woman's breasts by enriching fat from the stomach or thigh fat with stem cells before transplanting it into patients. It is hoped the method could be a more natural-looking alternative to artificial implants filled with salt water or silicone.
Scientists Clone Mice From Hair Follicle Stem Cell
Source: HealthDay News
Date: February 12, 2007
Summary:
A team of researchers from Rockefeller University reported they successfully cloned mice using stem cells from the rodents' hair follicle region. The stem cells come from adult mice, are relatively easy to obtain and inject, and may become a source of stem cells for animal cloning, the team said.
Date: February 12, 2007
Summary:
A team of researchers from Rockefeller University reported they successfully cloned mice using stem cells from the rodents' hair follicle region. The stem cells come from adult mice, are relatively easy to obtain and inject, and may become a source of stem cells for animal cloning, the team said.
Friday, February 09, 2007
Master switches found for adult blood stem cells
Source: Johns Hopkins Medical Institutions
Date: February 8, 2007
Summary:
Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders.
Date: February 8, 2007
Summary:
Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders.
Thursday, February 08, 2007
Carnegie Mellon Mechanical Engineering Researcher Proposes Development of Artificial Cells To Fight Disease
Source: Carnegie Mellon University
Date: February 7, 2007
Summary:
Carnegie Mellon University's Philip LeDuc predicts the use of artificially created cells could be a potential new therapeutic approach for treating diseases in an ever-changing world. LeDuc, an assistant professor of mechanical and biomedical engineering, penned an article for the January edition of Nature Nanotechnology Journal about the efficacy of using man-made cells to treat diseases without injecting drugs.
Date: February 7, 2007
Summary:
Carnegie Mellon University's Philip LeDuc predicts the use of artificially created cells could be a potential new therapeutic approach for treating diseases in an ever-changing world. LeDuc, an assistant professor of mechanical and biomedical engineering, penned an article for the January edition of Nature Nanotechnology Journal about the efficacy of using man-made cells to treat diseases without injecting drugs.
Cancer Biologists Identify Major Player In Cell Growth
Source: Brown University
Date: February 7, 2007
Summary:
When cells go about the business of dividing, they can get sidelined. Maybe there aren't enough nutrients. Maybe there aren't the right signals to resume multiplying. Either way, cells go quiet. The work, published online in Nature Cell Biology, introduces a new pathway that can be manipulated to control cell growth. Since cell growth is a fundamental biological process, the research may shed light on everything from miscarriages to muscular dystrophy. The main application, however, is cancer. Since a key characteristic of cancer cells is unchecked growth, the research identifies potential targets for new treatments.
Date: February 7, 2007
Summary:
When cells go about the business of dividing, they can get sidelined. Maybe there aren't enough nutrients. Maybe there aren't the right signals to resume multiplying. Either way, cells go quiet. The work, published online in Nature Cell Biology, introduces a new pathway that can be manipulated to control cell growth. Since cell growth is a fundamental biological process, the research may shed light on everything from miscarriages to muscular dystrophy. The main application, however, is cancer. Since a key characteristic of cancer cells is unchecked growth, the research identifies potential targets for new treatments.
Wednesday, February 07, 2007
World's First Adult Stem Cell Study Using Patient's Own Fat Tissue
Source: Texas Heart Institute
Date: February 7, 2007
Summary:
For the first time in humans, a heart failure patient received adult stem cells – taken from his own adipose (fat) tissue – which were processed and injected directly into the heart muscle with a special catheter. Francisco Fernandez-Avilés, M.D. performed the procedure in Madrid. The Texas Heart Institute at St. Luke’s Episcopal Hospital is leading the collaborative clinical trial which will involve 30 patients.
Date: February 7, 2007
Summary:
For the first time in humans, a heart failure patient received adult stem cells – taken from his own adipose (fat) tissue – which were processed and injected directly into the heart muscle with a special catheter. Francisco Fernandez-Avilés, M.D. performed the procedure in Madrid. The Texas Heart Institute at St. Luke’s Episcopal Hospital is leading the collaborative clinical trial which will involve 30 patients.
Tuesday, February 06, 2007
Lead, Mercury Inhibit Critical Cell Function
Source: University of Rochester Medical Center
Date: February 06, 2007
Summary:
Low levels of toxic substances cause critical stem cells in the central nervous system to prematurely shut down. That is the conclusion of a study published today in the on-line journal PLoS Biology. This research, which is the first to identify a common molecular trigger for the effects of toxicant exposure, may give scientists new insights into damage caused by toxicant exposure and new methods of evaluating the safety of chemicals.
Date: February 06, 2007
Summary:
Low levels of toxic substances cause critical stem cells in the central nervous system to prematurely shut down. That is the conclusion of a study published today in the on-line journal PLoS Biology. This research, which is the first to identify a common molecular trigger for the effects of toxicant exposure, may give scientists new insights into damage caused by toxicant exposure and new methods of evaluating the safety of chemicals.
Stem cells from fat tissue transplanted into heart
Source: Reuters
Posted: February 6, 2007 12:46pm ET
Summary:
Doctors at Spanish hospital have implanted adult stem cells extracted from a man’s fat tissue through liposuction into his heart, in an experimental treatment for angina and heart disease. Hospital officials cautioned that it take up to six months to see whether the cells repaired the damaged vessels.
Posted: February 6, 2007 12:46pm ET
Summary:
Doctors at Spanish hospital have implanted adult stem cells extracted from a man’s fat tissue through liposuction into his heart, in an experimental treatment for angina and heart disease. Hospital officials cautioned that it take up to six months to see whether the cells repaired the damaged vessels.
Spain claims stem cell first
Source: Guardian Unlimited - UK
Date: February 6, 2007
Summary:
The Guardian Unlimited reports:
"Surgeons at a Madrid hospital claim to be the first to use stem cells from a patient's fat tissue - extracted through liposuction - to treat the patient's heart."
Date: February 6, 2007
Summary:
The Guardian Unlimited reports:
"Surgeons at a Madrid hospital claim to be the first to use stem cells from a patient's fat tissue - extracted through liposuction - to treat the patient's heart."
Stem Cells May Help Heal Joint Injuries
Source: University of Guelph
Date: February 6, 2007
Summary:
As anyone who’s ever injured a knee or elbow will tell you, recovery can be a long and painful process. Cartilage is an exceptionally slow-healing tissue, and, until now, the missing or damaged tissue is often irreplaceable. Researchers at the University of Guelph are hoping stem cells might provide the needed tissue replacements and improve cartilage healing after joint injuries.
Date: February 6, 2007
Summary:
As anyone who’s ever injured a knee or elbow will tell you, recovery can be a long and painful process. Cartilage is an exceptionally slow-healing tissue, and, until now, the missing or damaged tissue is often irreplaceable. Researchers at the University of Guelph are hoping stem cells might provide the needed tissue replacements and improve cartilage healing after joint injuries.
Monday, February 05, 2007
Pre-Clinical Milestones for Sertolin Cell Replacement Technology: Insulin-Producing Cells Survive and Function without Anti-Rejection Drugs
Source: Sernova Corporation
February 05, 2007
Summary:
Sernova Corp. (TSX-V: SVA) announced its preliminary, preclinical animal studies have demonstrated long term survival and functioning of Sertolin, the Company's patented insulin producing cellular replacement therapy.
February 05, 2007
Summary:
Sernova Corp. (TSX-V: SVA) announced its preliminary, preclinical animal studies have demonstrated long term survival and functioning of Sertolin, the Company's patented insulin producing cellular replacement therapy.
Iran announces innovative new technique to repair spinal cord injuries
Source: Tehran Times - Tehran, Iran
Date: February 5, 2007
Summary:
The Islamic Republic of Iran officially announced that Iranian scientists have developed a new technique for treating patients with spinal cord injuries. In this method of Schwann cell transplantation, the Schwann cells are taken from the back of the patient’s leg (below the knee) and grown in the lab. They are then injected into the site of the injury. Researchers from the Spinal Cord Injury Treatment Center of the Tehran University of Medical Sciences have scientifically proven the efficacy of the new method through 30 operations on humans.
Date: February 5, 2007
Summary:
The Islamic Republic of Iran officially announced that Iranian scientists have developed a new technique for treating patients with spinal cord injuries. In this method of Schwann cell transplantation, the Schwann cells are taken from the back of the patient’s leg (below the knee) and grown in the lab. They are then injected into the site of the injury. Researchers from the Spinal Cord Injury Treatment Center of the Tehran University of Medical Sciences have scientifically proven the efficacy of the new method through 30 operations on humans.
Woven Scaffolds Could Improve Cartilage Repair
Source: Duke University Medical Center
Date: February 5, 2007
Summary:
DURHAM, N.C. -- Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells.
Date: February 5, 2007
Summary:
DURHAM, N.C. -- Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells.
First Heart Patient Treated in Adipose Stem Cell Trial; Cytori's Cardiovascular Stem Cell Study Initiated
Source: Cytori Therapeutics
Date: February 5, 2007
Summary:
Cytori Therapeutics and Hospital Gregorio Marañón in Madrid, Spain treated the first patient in Cytori's randomized clinical trial investigating the safety and feasibility of adipose-derived stem and regenerative cells as a therapy for cardiovascular disease. Patients in the study will receive their own adult stem and regenerative cells, thereby avoiding the risk of rejection or disease transmission that exists with donor stem cells and the controversy associated with embryonic stem cells. Once introduced into a patient's heart, the cells have shown preclinically to help the body improve blood supply that can restore circulation to the heart.
Date: February 5, 2007
Summary:
Cytori Therapeutics and Hospital Gregorio Marañón in Madrid, Spain treated the first patient in Cytori's randomized clinical trial investigating the safety and feasibility of adipose-derived stem and regenerative cells as a therapy for cardiovascular disease. Patients in the study will receive their own adult stem and regenerative cells, thereby avoiding the risk of rejection or disease transmission that exists with donor stem cells and the controversy associated with embryonic stem cells. Once introduced into a patient's heart, the cells have shown preclinically to help the body improve blood supply that can restore circulation to the heart.
Sunday, February 04, 2007
In Hematopoietic Stem Cells P21 Stops HIV-1 In Its Tracks
Source: Journal of Clinical Investigation via Medical News Today
Posted: February 4, 2007 - 8:00 PST
Summary:
Hematopoietic stem cells (HSCs) are one of the few cell types able to resist infection with HIV-1 despite expressing the cell surface molecules to which HIV-1 binds before entering a cell. In a study that appears in the February issue of the Journal of Clinical Investigation, researchers from Harvard Medical School, Boston, show that HSC expression of a protein is required for HSCs to be resistant to infection with HIV-1.
Posted: February 4, 2007 - 8:00 PST
Summary:
Hematopoietic stem cells (HSCs) are one of the few cell types able to resist infection with HIV-1 despite expressing the cell surface molecules to which HIV-1 binds before entering a cell. In a study that appears in the February issue of the Journal of Clinical Investigation, researchers from Harvard Medical School, Boston, show that HSC expression of a protein is required for HSCs to be resistant to infection with HIV-1.
Saturday, February 03, 2007
Sentry Enzyme Blocks Two Paths To Parkinson's Disease
Source: St. Jude Children's Research Hospital
Date: February 3, 2007
Summary:
The degeneration of brain cells that occurs in Parkinson's disease may be caused by either externally provoked cell death or internally initiated suicide when the molecule that normally prevents these fatal alternatives is missing, according to studies in mouse models by investigators at St. Jude Children's Research Hospital.
Date: February 3, 2007
Summary:
The degeneration of brain cells that occurs in Parkinson's disease may be caused by either externally provoked cell death or internally initiated suicide when the molecule that normally prevents these fatal alternatives is missing, according to studies in mouse models by investigators at St. Jude Children's Research Hospital.
Tumor-reactive T Cells Boosted By Hematopoietic Stem Cell Transplantation
Source: Journal of Clinical Investigation
Date: February 3, 2007
Summary:
Although treatment regimens involving the infusion of tumor-reactive T cells into patients with skin cancer (melanoma) have shown clinical benefit, there is plenty of room to improve the protocols to increase therapeutic benefit.
Date: February 3, 2007
Summary:
Although treatment regimens involving the infusion of tumor-reactive T cells into patients with skin cancer (melanoma) have shown clinical benefit, there is plenty of room to improve the protocols to increase therapeutic benefit.
Stem cells revolutionize spinal surgery
Source: Victoria Advocate - Victoria, Texas
Posted: February 03, 2007, 12:00 A.M.
Summary:
By extracting stem cells from the bone marrow in a patient's pelvis, doctors can mix the substance with ground bone and better fuse and stabilize spines following sensitive surgery - helping patients to recover and feel less back pain quicker.
Posted: February 03, 2007, 12:00 A.M.
Summary:
By extracting stem cells from the bone marrow in a patient's pelvis, doctors can mix the substance with ground bone and better fuse and stabilize spines following sensitive surgery - helping patients to recover and feel less back pain quicker.
Friday, February 02, 2007
Lipid plays big role in embryonic development
Source: Medical College of Georgia
Date: February 2, 2007
Summary:
A little-known lipid plays a big role in helping us grow from a hollow sphere of stem cells into human beings, researchers have found. They found that in the first few days of life, ceramide helps stem cells line up to form the primitive ectoderm from which embryonic tissues develop, says Dr. Erhard Bieberich, biochemist at the Medical College of Georgia.
Date: February 2, 2007
Summary:
A little-known lipid plays a big role in helping us grow from a hollow sphere of stem cells into human beings, researchers have found. They found that in the first few days of life, ceramide helps stem cells line up to form the primitive ectoderm from which embryonic tissues develop, says Dr. Erhard Bieberich, biochemist at the Medical College of Georgia.
Stem cell find could advance pancreatic cancer treatment
Source: Reuters
Date: February 2, 2007
Summary:
Researchers have discovered a small population of stem cells in pancreatic cancer that appear to drive tumor growth, opening the door for a potential new approach for treating this particularly deadly disease. Writing in the February 1 edition of the journal Cancer Research, University of Michigan scientists said finding cancer stem cells in pancreatic tumors could lead to the development of drugs intended to target and kill these cells.
Date: February 2, 2007
Summary:
Researchers have discovered a small population of stem cells in pancreatic cancer that appear to drive tumor growth, opening the door for a potential new approach for treating this particularly deadly disease. Writing in the February 1 edition of the journal Cancer Research, University of Michigan scientists said finding cancer stem cells in pancreatic tumors could lead to the development of drugs intended to target and kill these cells.
Thursday, February 01, 2007
Subset of stem cells drives pancreatic cancer: Findings opens new path for treating deadly disease
Source: Reuters
Date: February 1, 2007
Summary:
Researchers have discovered a small population of stem cells in pancreatic cancer that appear to drive tumor growth, opening the door for a potential new approach for treating this particularly deadly disease.
Date: February 1, 2007
Summary:
Researchers have discovered a small population of stem cells in pancreatic cancer that appear to drive tumor growth, opening the door for a potential new approach for treating this particularly deadly disease.
Scientists Identify Pancreatic Cancer Stem Cells: Findings Bolster Theory That Stem Cells Are at the Root of Cancer
Source: American Association for Cancer Research
Date: February 1, 2007
Summary:
Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.
Date: February 1, 2007
Summary:
Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.
U-M researchers identify stem cells in pancreatic cancer
Source: University of Michigan Health System
Date: February 1, 2007
Summary:
Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.
Date: February 1, 2007
Summary:
Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.
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