To All Readers of Ben's Stem Cell News:
I will be away at The Stem Cell Summit in Boston this week and will have limited internet access, so I will be blogging sporadically for the next few days. I will continue with the same quality updates on the latest stem cell research and science news when I return later this week.
Ben Kaplan
Publisher
Ben's Stem Cell News
Sunday, September 30, 2007
Saturday, September 29, 2007
Stem-cell treatment for MS tested
Source: United Press International
Posted: September 29, 2007 at 12:31 AM EDT
Summary:
A clinical trial in Britain is testing a new stem-cell treatment researchers hope will undo central nervous system damage in patients with multiple sclerosis.
Posted: September 29, 2007 at 12:31 AM EDT
Summary:
A clinical trial in Britain is testing a new stem-cell treatment researchers hope will undo central nervous system damage in patients with multiple sclerosis.
Friday, September 28, 2007
Stem cell injection trial 'raises hope of MS cure'
Source: Daily Mail
Posted: 28 September 2007 10:18am BST
Summary:
The Daily Mail reports on a new trial in Britain using bone marrow stem cells to treat multiple sclerosis:
"A pioneering new treatment which could help thousands of multiple sclerosis suffers "recover" from the incurable disease is being trialled for the first time at a British hospital. The patients will be injected with bone marrow stem cells, which researchers hope will repair damaged areas of the brain and spinal cord and 'reverse' their physical decline."
Posted: 28 September 2007 10:18am BST
Summary:
The Daily Mail reports on a new trial in Britain using bone marrow stem cells to treat multiple sclerosis:
"A pioneering new treatment which could help thousands of multiple sclerosis suffers "recover" from the incurable disease is being trialled for the first time at a British hospital. The patients will be injected with bone marrow stem cells, which researchers hope will repair damaged areas of the brain and spinal cord and 'reverse' their physical decline."
Thursday, September 27, 2007
Stem cell trials raise multiple sclerosis hopes
Source: Daily Telegraph
Posted: 28 September 2007 12:54am BST
Summary:
The Daily Telegraph reports on a new trial using adult bone marrow stem cells to attempt to treat Multiple Sclerosis:
"Tens of thousands of patients with MS could benefit from the revolutionary treatment if the tests taking place at the Frenchay hospital, near Bristol, are successful. Patients are injected with stem cells taken from their own bone marrow, not from umbilical cords The procedure involves patients being injected with stem cells taken from their own bone marrow, in the hope that they will travel to damaged parts of the brain and repair them."
Posted: 28 September 2007 12:54am BST
Summary:
The Daily Telegraph reports on a new trial using adult bone marrow stem cells to attempt to treat Multiple Sclerosis:
"Tens of thousands of patients with MS could benefit from the revolutionary treatment if the tests taking place at the Frenchay hospital, near Bristol, are successful. Patients are injected with stem cells taken from their own bone marrow, not from umbilical cords The procedure involves patients being injected with stem cells taken from their own bone marrow, in the hope that they will travel to damaged parts of the brain and repair them."
Wednesday, September 26, 2007
Study of bone marrow stem cells in multiple sclerosis
Source: University of Bristol
Date: September 26, 2007
Summary:
A new pilot clinical trial to test bone marrow stem cell therapy with a small group of patients with multiple sclerosis has started at Frenchay Hospital. The aim of the trial, conducted by the University of Bristol and North Bristol NHS Trust, is to find out what effects, good or bad, it has on patients with MS, and their disability.
Date: September 26, 2007
Summary:
A new pilot clinical trial to test bone marrow stem cell therapy with a small group of patients with multiple sclerosis has started at Frenchay Hospital. The aim of the trial, conducted by the University of Bristol and North Bristol NHS Trust, is to find out what effects, good or bad, it has on patients with MS, and their disability.
Tuesday, September 25, 2007
Stem cell therapy 'could cut liver transplants'
Source: Daily Telegraph
Last Updated: 2:38am BST 26/09/2007
Summary:
The Daily Telegraph reports scientists have developed a new way to treat liver failure using stem cells:
"Scientists have discovered a new way of treating liver failure that could save the lives of thousands of patients on transplant waiting lists. The technique involves inserting stem cells into the damaged organ so that it is encouraged to repair itself and create new tissue. According to the researchers, the treatment will allow patients to live long enough for a new organ to found and could even enable the liver to completely heal itself so a transplant is no longer needed."
Last Updated: 2:38am BST 26/09/2007
Summary:
The Daily Telegraph reports scientists have developed a new way to treat liver failure using stem cells:
"Scientists have discovered a new way of treating liver failure that could save the lives of thousands of patients on transplant waiting lists. The technique involves inserting stem cells into the damaged organ so that it is encouraged to repair itself and create new tissue. According to the researchers, the treatment will allow patients to live long enough for a new organ to found and could even enable the liver to completely heal itself so a transplant is no longer needed."
Immune system modulation can halt liver failure in animals
Source: Massachusetts General Hospital
Date: September 25, 2007
Summary:
Massachusetts General Hospital (MGH) researchers have a developed a totally new approach to treating liver failure – manipulating the immune response. If the results of the animal study can be applied in human patients, the approach may be able to keep patients alive until donor organs become available or to support liver function until the organ can regenerate itself, eliminating the need for a transplant. The findings are being reported in the journal PLOS One.
Date: September 25, 2007
Summary:
Massachusetts General Hospital (MGH) researchers have a developed a totally new approach to treating liver failure – manipulating the immune response. If the results of the animal study can be applied in human patients, the approach may be able to keep patients alive until donor organs become available or to support liver function until the organ can regenerate itself, eliminating the need for a transplant. The findings are being reported in the journal PLOS One.
Stem Cells Show Promise For Treating Huntington's Disease
Source: University of Rochester Medical Center
Date: September 25, 2007
Summary:
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington’s disease – a fatal disorder for which there is currently no cure or even a treatment to slow the disease. In a paper published Sept. 20 in the Journal of Clinical Investigation, scientists at the University of Rochester Medical Center have shown how stem-cell therapy might someday be used to treat the disease. The team used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s. The mice that were treated lived significantly longer, were healthier, and had many more new, viable brain cells than their counterparts that did not receive the treatment.
Date: September 25, 2007
Summary:
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington’s disease – a fatal disorder for which there is currently no cure or even a treatment to slow the disease. In a paper published Sept. 20 in the Journal of Clinical Investigation, scientists at the University of Rochester Medical Center have shown how stem-cell therapy might someday be used to treat the disease. The team used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s. The mice that were treated lived significantly longer, were healthier, and had many more new, viable brain cells than their counterparts that did not receive the treatment.
Monday, September 24, 2007
Scientists discover how cancer may take hold
Source: Carnegie Institution
Date: September 24, 2007
Summary:
A team, led by researchers at the Carnegie Institution, has found a key biochemical cycle that suppresses the immune response, thereby allowing cancer cells to multiply unabated. The research shows how the biomolecules responsible for healthy T-cells, the body’s first defenders against hostile invaders, are quashed, permitting the invading cancer to spread. The same cycle could also be involved in autoimmune diseases such as multiple sclerosis. The work is published in the September 25, 2007 issue of PLoS Biology.
Date: September 24, 2007
Summary:
A team, led by researchers at the Carnegie Institution, has found a key biochemical cycle that suppresses the immune response, thereby allowing cancer cells to multiply unabated. The research shows how the biomolecules responsible for healthy T-cells, the body’s first defenders against hostile invaders, are quashed, permitting the invading cancer to spread. The same cycle could also be involved in autoimmune diseases such as multiple sclerosis. The work is published in the September 25, 2007 issue of PLoS Biology.
Friday, September 21, 2007
Study: Sibling umbilical blood transplant cures sickle-cell kids
Source: San Francisco Chronicle
Date: September 21, 2007
Summary:
Children with sickle cell disease were cured following umbilical cord blood transplants from their siblings, according to findings reported Thursday in Washington, D.C., by doctors from Children's Hospital Oakland.
Date: September 21, 2007
Summary:
Children with sickle cell disease were cured following umbilical cord blood transplants from their siblings, according to findings reported Thursday in Washington, D.C., by doctors from Children's Hospital Oakland.
Thursday, September 20, 2007
Testicles yield stem cells in science breakthrough
Source: Australian Broadcasting Corporation
Posted Thu Sep 20, 2007 5:18pm AEST
Updated Thu Sep 20, 2007 5:25pm AEST
Summary:
Scientists say they have isolated stem cells from the testes of male mice, extract them and reprogram them into blood vessels, heart cells and tissue. They say if the results can be reproduced in humans, the technology could help get around the ethical concerns associated with the use of embryonic stem cells and could be used to help treat Parkinson's, heart disease, strokes and cancer.
Posted Thu Sep 20, 2007 5:18pm AEST
Updated Thu Sep 20, 2007 5:25pm AEST
Summary:
Scientists say they have isolated stem cells from the testes of male mice, extract them and reprogram them into blood vessels, heart cells and tissue. They say if the results can be reproduced in humans, the technology could help get around the ethical concerns associated with the use of embryonic stem cells and could be used to help treat Parkinson's, heart disease, strokes and cancer.
Stem Cells Derived from Adult Testes Produce Wide Range of Tissue Types for Therapeutic Organ Regeneration
Source: Howard Hughes Medical Institute
Date: September 20, 2007
Summary:
After a decade of research, Howard Hughes Medical Institute scientists have succeeded in reprogramming adult stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue. The research offers a promising new source of stem cells for use in organ regeneration studies.
Date: September 20, 2007
Summary:
After a decade of research, Howard Hughes Medical Institute scientists have succeeded in reprogramming adult stem cells from the testes of male mice into functional blood vessels and contractile cardiac tissue. The research offers a promising new source of stem cells for use in organ regeneration studies.
Scientists Find Less Controversial Stem Cell
Source: NPR
Date: September 20, 2007
Summary:
Scientists in New York say they may have found cells that are just as promising, but do not start with an embryo. An NPR radio broadcast accompanies this story.
Date: September 20, 2007
Summary:
Scientists in New York say they may have found cells that are just as promising, but do not start with an embryo. An NPR radio broadcast accompanies this story.
Human testicles can provide stem cells
Source: United Press International
Published: September 20, 2007 at 9:28 AM EDT
Summary:
U.S. scientists said adult stem cells found in human testicles might be used in place of controversial embryonic stem cells to help fight diseases.
Published: September 20, 2007 at 9:28 AM EDT
Summary:
U.S. scientists said adult stem cells found in human testicles might be used in place of controversial embryonic stem cells to help fight diseases.
Using testicles to fix the brain, heart and blood
Source: The Globe and Mail
Posted: September 20, 2007 at 4:19 AM EDT
Summary:
Men have a source of potentially life-saving stem cells between their legs. A team of American researchers has found a way to easily identify stem cells in the testicles of adult mice that can be coaxed to turn into brain cells, muscle cells, heart cells, blood cells and even blood vessels. One day, they say, male patients may be able to turn to their own testicles as a source of stem cells to repair an ailing heart or kidney or to fix the brain damage caused by Alzheimer's or Parkinson's disease.
Posted: September 20, 2007 at 4:19 AM EDT
Summary:
Men have a source of potentially life-saving stem cells between their legs. A team of American researchers has found a way to easily identify stem cells in the testicles of adult mice that can be coaxed to turn into brain cells, muscle cells, heart cells, blood cells and even blood vessels. One day, they say, male patients may be able to turn to their own testicles as a source of stem cells to repair an ailing heart or kidney or to fix the brain damage caused by Alzheimer's or Parkinson's disease.
Wednesday, September 19, 2007
Obtaining Stem Cells From Adult Testicles, An Alternative To Embryonic Stem Cells, actually expanding the small population o
Source: Medical News Today
Article Date: 19 September 2007 - 16:00 PDT
Summary:
Adult testicles could one day become a common source for stem cells to cultivate a host of tissue types to combat disease, while at the same time avoiding the ethical resistance to embryonic stem cells, say researchers from Weill Cornell Medical College. Using SPCs (spermatogonial progenitor stem cells) which came from the testes of mice, the scientists were able to tweak them in the lab to form MASCs (multi-potent adult spermatogonial-derived stem cells). These cells were developed into endothelial (working blood vessel) cells and tissue, cardiac cells, brain cells and a range of other cell types.
Article Date: 19 September 2007 - 16:00 PDT
Summary:
Adult testicles could one day become a common source for stem cells to cultivate a host of tissue types to combat disease, while at the same time avoiding the ethical resistance to embryonic stem cells, say researchers from Weill Cornell Medical College. Using SPCs (spermatogonial progenitor stem cells) which came from the testes of mice, the scientists were able to tweak them in the lab to form MASCs (multi-potent adult spermatogonial-derived stem cells). These cells were developed into endothelial (working blood vessel) cells and tissue, cardiac cells, brain cells and a range of other cell types.
Global Breakthrough In Animal Experiment: Stem Cells To Repair The Lungs, Highly Promising Results From British Team
Source: European Respiratory Society
Article Date: 19 September 2007 - 15:00 PDT
Summary:
Researchers from London's Imperial College have successfully implanted lung cells grown from embryonic stem cells into the lungs of mice. This worldwide breakthrough, presented to the annual Congress of the European Respiratory Society (ERS) in Stockholm, opens up exciting new horizons for the treatment of lung disease.
Article Date: 19 September 2007 - 15:00 PDT
Summary:
Researchers from London's Imperial College have successfully implanted lung cells grown from embryonic stem cells into the lungs of mice. This worldwide breakthrough, presented to the annual Congress of the European Respiratory Society (ERS) in Stockholm, opens up exciting new horizons for the treatment of lung disease.
Testicular Stem Cells Show Their Spots: Tracking down powerful adult stem cells in mouse testes may benefit humans, too
Source: Scientific American
Date: September 19, 2007
Summary:
Researchers say they have found a way to pluck out a potent type of stem cell from the testes of adult mice and transform it into other kinds of tissue, including heart muscle and blood vessels.
Date: September 19, 2007
Summary:
Researchers say they have found a way to pluck out a potent type of stem cell from the testes of adult mice and transform it into other kinds of tissue, including heart muscle and blood vessels.
Stem Cells From Testes Produce Wide Range of Tissue Types
Source: HealthDay News
Posted: September 19, 2007; 4:00 PM EDT
Summary;
HealthDay News reports researchers have turned adult stem cells from male mice testes into functioning cell types:
"U.S. researchers say they've successfully reprogrammed adult stem cells from the testes of male mice into a wide variety of cell types, including functional blood vessels, contractile cardiac tissue, and brain cells. If the same can be done with adult testes stem cells from humans, they may offer a source of new therapies to treat men with health problems such as heart disease, vascular diseases, diabetes, stroke, Parkinson's, Alzheimer's, and even cancer, the researchers said."
Posted: September 19, 2007; 4:00 PM EDT
Summary;
HealthDay News reports researchers have turned adult stem cells from male mice testes into functioning cell types:
"U.S. researchers say they've successfully reprogrammed adult stem cells from the testes of male mice into a wide variety of cell types, including functional blood vessels, contractile cardiac tissue, and brain cells. If the same can be done with adult testes stem cells from humans, they may offer a source of new therapies to treat men with health problems such as heart disease, vascular diseases, diabetes, stroke, Parkinson's, Alzheimer's, and even cancer, the researchers said."
Male sex organ new source of stem cells
Source: Agence France Presse (AFP)
Posted: September 19, 2007 3:22 PM EDT
Summary:
Agence France Presse (AFP) reports researchers isolated adult stem cells in mouse testicles:
"A man's testicles could one day provide a plentiful and accessible supply of adult stems cells to help him fight off disease or regenerate damaged organs, according to a study published Wednesday. Researchers at Weill Cornell Medical College in New York have already isolated the multi-purpose cells in mice, and successfully coaxed them to grow into cardiac cells, brain cells and working blood vessel tissue."
Posted: September 19, 2007 3:22 PM EDT
Summary:
Agence France Presse (AFP) reports researchers isolated adult stem cells in mouse testicles:
"A man's testicles could one day provide a plentiful and accessible supply of adult stems cells to help him fight off disease or regenerate damaged organs, according to a study published Wednesday. Researchers at Weill Cornell Medical College in New York have already isolated the multi-purpose cells in mice, and successfully coaxed them to grow into cardiac cells, brain cells and working blood vessel tissue."
Cells that make sperm make stem cells, too – study
Source: Reuters
Posted: September 19, 2007 3:54 p.m. EDT
Summary:
Reuters reports researchers have isolated stem cells from tissue in testicles and turned them into different cell types that might be able to treat diseases and injuries in humans:
"Stem cells that normally make sperm can be taught to make other tissues as well, perhaps offering men a medical repair kit, U.S. researchers said Wednesday. They found a way to easily pick the cells out from other tissue in the testicles and to grow them into batches big enough to use medically. This provides a new source of stem cells, the body's master cells, which experts hope can be used to treat injuries, replace diseased tissue and perhaps even regenerate organs."
Posted: September 19, 2007 3:54 p.m. EDT
Summary:
Reuters reports researchers have isolated stem cells from tissue in testicles and turned them into different cell types that might be able to treat diseases and injuries in humans:
"Stem cells that normally make sperm can be taught to make other tissues as well, perhaps offering men a medical repair kit, U.S. researchers said Wednesday. They found a way to easily pick the cells out from other tissue in the testicles and to grow them into batches big enough to use medically. This provides a new source of stem cells, the body's master cells, which experts hope can be used to treat injuries, replace diseased tissue and perhaps even regenerate organs."
To Evade Chemotherapy, Some Cancer Cells Mimic Stem Cells
Source: American Association for Cancer Research
Date: September 19, 2007
Summary:
Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association for Cancer Research's second International Conference on Molecular Diagnostics in Cancer Therapeutic Development.
Date: September 19, 2007
Summary:
Anti-cancer treatments often effectively shrink the size of tumors, but some might have an opposite effect, actually expanding the small population of cancer stem cells believed to drive the disease, according to findings presented today in Atlanta, Georgia at the American Association for Cancer Research's second International Conference on Molecular Diagnostics in Cancer Therapeutic Development.
Study: Testicle Stem Cells May Ward Off Disease
Source: Fox News
Date: September 19, 2007
Summary:
Stem cells, found in male testicles, may be used to create tissue samples to help men fight off disease. Using spermatogonial progenitor stem cells (SPCs), which lie within a specific area of the testes and generate the precursors to sperm, researchers from the Weill Cornell Medical College in New York City were able to develop working cells and tissue types.
Date: September 19, 2007
Summary:
Stem cells, found in male testicles, may be used to create tissue samples to help men fight off disease. Using spermatogonial progenitor stem cells (SPCs), which lie within a specific area of the testes and generate the precursors to sperm, researchers from the Weill Cornell Medical College in New York City were able to develop working cells and tissue types.
Stem cells in adult testes provide alternative to embryonic stem cells for organ regeneration
Source: Weill Cornell Medical College
Date: September 19, 2007
Summary:
Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. Using spermatogonial progenitor stem cells (SPCs) obtained from the mouse's testes, the researchers were able to redirect the cells' development in the lab to form so-called "multi-potent adult spermatogonial-derived stem cells" (MASCs). It was these cells that went on to develop into working blood vessel (endothelial) cells and tissue, as well as cardiac cells, brain cells and a host of other cell types.
Date: September 19, 2007
Summary:
Easily accessed and plentiful, adult stem cells found in a male patient's testicles might someday be used to create a wide range of tissue types to help him fight disease -- getting around the need for more controversial embryonic stem cells. Using spermatogonial progenitor stem cells (SPCs) obtained from the mouse's testes, the researchers were able to redirect the cells' development in the lab to form so-called "multi-potent adult spermatogonial-derived stem cells" (MASCs). It was these cells that went on to develop into working blood vessel (endothelial) cells and tissue, as well as cardiac cells, brain cells and a host of other cell types.
Testicle stem cell harvest plan
Source: BBC News
Published: 2007/09/19 17:00:33 GMT
Summary:
BBC News reports scientists have found stem cells in adult testicles that may enable treatments for diseases:
"A man's testicles might be a source of stem cells to help him fight serious diseases, US scientists have shown. They extracted early-stage sperm cells from mice, then turned them into cells capable of becoming different tissues. Writing in Nature, the Weill Cornell Medical College team said their work might lead to treatments for illnesses such as Alzheimer's and diabetes. However, some doubt has been expressed on the willingness of men to undergo the procedure to extract the cells."
Published: 2007/09/19 17:00:33 GMT
Summary:
BBC News reports scientists have found stem cells in adult testicles that may enable treatments for diseases:
"A man's testicles might be a source of stem cells to help him fight serious diseases, US scientists have shown. They extracted early-stage sperm cells from mice, then turned them into cells capable of becoming different tissues. Writing in Nature, the Weill Cornell Medical College team said their work might lead to treatments for illnesses such as Alzheimer's and diabetes. However, some doubt has been expressed on the willingness of men to undergo the procedure to extract the cells."
Unique cell growth technology is created
Source: United Press International
Posted: September 19, 2007 at 12:27 PM
Summary:
British scientists have created a laboratory technology that can grow stem cells and other tissue in a manner similar to how cells grow in the body.
Posted: September 19, 2007 at 12:27 PM
Summary:
British scientists have created a laboratory technology that can grow stem cells and other tissue in a manner similar to how cells grow in the body.
Cell growth technology promises more successful drug development
Source: Durham University
Date: 19 September 2007
Summary:
Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body. The technology, developed and patented by scientists at Durham University and its spin-out company ReInnervate Limited, is a plastic scaffold which allows cells to be grown in a more realistic three-dimensional (3D) form compared to the traditional flat surface of a Petri dish. Evidence gathered by the research team shows that the technology is a cheap and straightforward way of cultivating cells in 3D. Using it could lead to more successful drug development programmes and a reduction in unnecessary tests on animals.
Date: 19 September 2007
Summary:
Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body. The technology, developed and patented by scientists at Durham University and its spin-out company ReInnervate Limited, is a plastic scaffold which allows cells to be grown in a more realistic three-dimensional (3D) form compared to the traditional flat surface of a Petri dish. Evidence gathered by the research team shows that the technology is a cheap and straightforward way of cultivating cells in 3D. Using it could lead to more successful drug development programmes and a reduction in unnecessary tests on animals.
Tuesday, September 18, 2007
Sexual function affected by stem cell transplant according to long-term study
Source: American Society of Hematology
Date: September 18, 2007
Summary:
A long-term study found that a type of stem cell transplant used for patients with life-threatening diseases, such as leukemia and lymphoma, results in decreased sexual function and activity for recipients. Further, males are likely to recover from these changes over time, while the sexuality of female patients remains compromised. In addition, neither male nor female long-term cancer survivors regained levels of sexual activity and function equal to those of their peers who have not had cancer, according to a Blood First Edition Paper prepublished online today.
Date: September 18, 2007
Summary:
A long-term study found that a type of stem cell transplant used for patients with life-threatening diseases, such as leukemia and lymphoma, results in decreased sexual function and activity for recipients. Further, males are likely to recover from these changes over time, while the sexuality of female patients remains compromised. In addition, neither male nor female long-term cancer survivors regained levels of sexual activity and function equal to those of their peers who have not had cancer, according to a Blood First Edition Paper prepublished online today.
Stem cells can repair diseased lungs: study
Source: Agence France Presse (AFP)
Date: September 18, 2007
Summary:
Researchers have discovered that Lung cells grown from mouse embryo stem cells have been successfully implanted into the lungs of mice, a breakthrough that could one day help humans with lung disease.
Date: September 18, 2007
Summary:
Researchers have discovered that Lung cells grown from mouse embryo stem cells have been successfully implanted into the lungs of mice, a breakthrough that could one day help humans with lung disease.
T vs. B: Re-engineered Human T Cells Effectively Target and Kill Cancerous B Cells
Source: American Association for Cancer Research
Date: September 18, 2007
Summary
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).
Date: September 18, 2007
Summary
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia (ALL), according to researchers at Memorial Sloan-Kettering Cancer Center (MSKCC).
Stem cells show potential to repair lungs in mice
Source: Reuters
Posted: September 18, 2007 10:12 am EDT
Summary:
British researchers have successfully implanted lung cells grown from embryonic stem cells into the lungs of mice in a move that may one day provide treatments for humans with severe breathing problems.
Posted: September 18, 2007 10:12 am EDT
Summary:
British researchers have successfully implanted lung cells grown from embryonic stem cells into the lungs of mice in a move that may one day provide treatments for humans with severe breathing problems.
Monday, September 17, 2007
Cell death in sparrow brains may provide clues in age-related human diseases
Source: University of Washington
Date: September 17, 2007
Summary:
A remarkable change takes place in the brains of tiny songbirds every year, and some day the mechanism controlling that change may help researchers develop treatments for age-related degenerative diseases of the brain such as Parkinson's and dementia.
Date: September 17, 2007
Summary:
A remarkable change takes place in the brains of tiny songbirds every year, and some day the mechanism controlling that change may help researchers develop treatments for age-related degenerative diseases of the brain such as Parkinson's and dementia.
Stem cells are isolated in womb tissue
Source: United Press International
Posted: September 17, 2007 2:29 PM ET
Summary:
Australian scientists have found a way of identifying probable stem cells in the lining of women’s wombs. The finding by Monash University researchers opens the possibility of using the stem cells for tissue engineering applications, such as creating natural tissue to repair pelvic floor prolapse, a common condition that affects more than 50 percent of women after childbirth.
Posted: September 17, 2007 2:29 PM ET
Summary:
Australian scientists have found a way of identifying probable stem cells in the lining of women’s wombs. The finding by Monash University researchers opens the possibility of using the stem cells for tissue engineering applications, such as creating natural tissue to repair pelvic floor prolapse, a common condition that affects more than 50 percent of women after childbirth.
Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
Source: Tengion Inc.
Date: September 17, 2007
Summary:
Tengion, Inc., a leader in regenerative medicine, announced today it has initiated a Phase 2 multi-center clinical trial of its neo-bladder construct, derived from a patient’s own cells. The U.S.-based study is being conducted in 10 adult patients with neurogenic bladder due to spinal cord injuries. Neurogenic bladder is a condition that can occur due to spinal cord injury and may lead to kidney failure and incontinence, even when patients receive optimal medical treatment.
Date: September 17, 2007
Summary:
Tengion, Inc., a leader in regenerative medicine, announced today it has initiated a Phase 2 multi-center clinical trial of its neo-bladder construct, derived from a patient’s own cells. The U.S.-based study is being conducted in 10 adult patients with neurogenic bladder due to spinal cord injuries. Neurogenic bladder is a condition that can occur due to spinal cord injury and may lead to kidney failure and incontinence, even when patients receive optimal medical treatment.
Saturday, September 15, 2007
A molecule that protects from neuronal disorders
Source: European Molecular Biology Laboratory
Date: September 15, 2007
Summary:
Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation -, result from abnormal migration of nerve cells during the development of the brain. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy, have now discovered that a protein that helps organising the cells’ skeleton is crucial for preventing such defects.
Date: September 15, 2007
Summary:
Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly – a form of mental retardation -, result from abnormal migration of nerve cells during the development of the brain. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy, have now discovered that a protein that helps organising the cells’ skeleton is crucial for preventing such defects.
Friday, September 14, 2007
Help for growing hearts
Source: Newsday
Date: September 14, 2007
Summary:
Newsday reports doctors have successfully created functioning heart valves from human bone marrow stem cells:
"Doctors say they are a significant step closer to producing stem-cell-generated heart valves for children, structures that can grow with the child, eliminating the need for repeat surgeries as now is the case when conventional methods are used. Medical researchers at Children's Hospital Boston say they can create the valves from stem cells derived from the bone marrow and coax those cells in the lab to grow into a complete, functioning heart valve. The process is called tissue-engineering, an area of science in which investigators are attempting to develop replacement parts for structures damaged by disease and age."
Date: September 14, 2007
Summary:
Newsday reports doctors have successfully created functioning heart valves from human bone marrow stem cells:
"Doctors say they are a significant step closer to producing stem-cell-generated heart valves for children, structures that can grow with the child, eliminating the need for repeat surgeries as now is the case when conventional methods are used. Medical researchers at Children's Hospital Boston say they can create the valves from stem cells derived from the bone marrow and coax those cells in the lab to grow into a complete, functioning heart valve. The process is called tissue-engineering, an area of science in which investigators are attempting to develop replacement parts for structures damaged by disease and age."
Thursday, September 13, 2007
Keeping The Right Balance - New Insights Into The Control Of Stem Cells
Source: Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch
Article Date: 13 September 2007 - 17:00 PDT
Summary:
In recent years, researchers have gained ever more insight into the regulation of stem cells and their role in self-renewal and repair mechanisms. One important stem cell regulator discovered is now known as the Wnt signaling pathway. It plays a crucial role in embryonic development, cell growth (proliferation), and maturation of cells into specialized cells (differentiation). This pathway is also an important regulator of stem cells.
Article Date: 13 September 2007 - 17:00 PDT
Summary:
In recent years, researchers have gained ever more insight into the regulation of stem cells and their role in self-renewal and repair mechanisms. One important stem cell regulator discovered is now known as the Wnt signaling pathway. It plays a crucial role in embryonic development, cell growth (proliferation), and maturation of cells into specialized cells (differentiation). This pathway is also an important regulator of stem cells.
Gene knockout extends life of mice with ALS
Source: Nature
Date: 13 September 2007
Summary:
Knocking out a single gene nearly doubles the lifespan of mice with the animal model of Lou Gehrig's disease, suggesting that the gene may one day become a target for therapies in humans.
Date: 13 September 2007
Summary:
Knocking out a single gene nearly doubles the lifespan of mice with the animal model of Lou Gehrig's disease, suggesting that the gene may one day become a target for therapies in humans.
Fetal Neurons Still Operate in Adult Brain. The question is: Why?
Source: Scientific American
Date: September 13, 2007
Summary:
A population of nerve cells crucial for proper brain wiring may serve a completely different function in adult and fetal brains, according to a new study in The Journal of Neuroscience.
Date: September 13, 2007
Summary:
A population of nerve cells crucial for proper brain wiring may serve a completely different function in adult and fetal brains, according to a new study in The Journal of Neuroscience.
Stem cell find to shed light on womb disorders
Source: The Mercury - Australia
Posted: September 13, 2007 03:31pm
Summary:
AUSTRALIAN scientists have made a stem cell breakthrough that could shed light on mysterious reproductive ailments suffered by millions of women. Researchers at Monash University have identified stem cells in the lining of women's wombs that have the ability to switch into a range of fat, bone or muscle cells as needed.
Posted: September 13, 2007 03:31pm
Summary:
AUSTRALIAN scientists have made a stem cell breakthrough that could shed light on mysterious reproductive ailments suffered by millions of women. Researchers at Monash University have identified stem cells in the lining of women's wombs that have the ability to switch into a range of fat, bone or muscle cells as needed.
Scientists discover how to isolate stem cells in womb tissue
Source: European Society for Human Reproduction and Embryology
Date: September 13, 2007
Summary:
Scientists in Australia have found a way of identifying probable stem cells in the lining of women’s wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors. Pelvic floor prolapse is a common condition, affecting over 50% of women after childbirth; around one in ten women have surgery and a third of these women require repeated operations to correct the problem.
Date: September 13, 2007
Summary:
Scientists in Australia have found a way of identifying probable stem cells in the lining of women’s wombs. The finding opens up the possibility of using the stem cells for tissue engineering applications such as building up natural tissue to repair prolapsed pelvic floors. Pelvic floor prolapse is a common condition, affecting over 50% of women after childbirth; around one in ten women have surgery and a third of these women require repeated operations to correct the problem.
Wednesday, September 12, 2007
Stem Cell Therapy Disappoints Against Rare Kidney Ailment
Source: HealthDay News
Date: September 12, 2007
Summary:
In a disheartening result that confounds existing research, a team in France says a new stem cell therapy for a rare kidney disease is no better than the usual chemotherapy-only approach. But there's also some good news. The study doesn't reject the possibility that stem-cell transplants may be a better bet in facilities that specialize in the procedure.
Date: September 12, 2007
Summary:
In a disheartening result that confounds existing research, a team in France says a new stem cell therapy for a rare kidney disease is no better than the usual chemotherapy-only approach. But there's also some good news. The study doesn't reject the possibility that stem-cell transplants may be a better bet in facilities that specialize in the procedure.
Unique Role for Blood Formation Gene Identified: DMS research reveals new pathway for stem cell turnover
Source: Dartmouth Medical School
Date: September 12, 2007
Summary:
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research reveals an unexpected role for the gene in sustaining the adult blood-forming system, and opens novel strategies for targeting the gene, which is often involved in a type of childhood leukemia.
Date: September 12, 2007
Summary:
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research reveals an unexpected role for the gene in sustaining the adult blood-forming system, and opens novel strategies for targeting the gene, which is often involved in a type of childhood leukemia.
Cancer stem cell subpopulation drives metastasis of human pancreatic cancer
Source: Cell Press
Date: September 12, 2007
Summary:
Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer. The research, published by Cell Press in the September issue of the journal Cell Stem Cell, provides insight into the role of CSCs in cancer initiation, progression, and metastasis and suggests new directions for development of more effective therapeutics.
Date: September 12, 2007
Summary:
Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer. The research, published by Cell Press in the September issue of the journal Cell Stem Cell, provides insight into the role of CSCs in cancer initiation, progression, and metastasis and suggests new directions for development of more effective therapeutics.
Putting Stem Cell Research On The Fast Track: Two groups of researchers provide tools to speed stem cell research
Source: Rensselaer Polytechnic Institute
Date: September 12, 2007
Summary:
Engineers at Rensselaer Polytechnic Institute have developed tools to help solve two of the main problems slowing the progress of stem cell research -- how to quickly test stem cell response to different drugs or genes, and how to create a large supply of healthy, viable stem cells to study from only a few available cells. The researchers have created methods to study millions of stems cells on devices the size of a standard microscope slide. The techniques enable thousands of individual stem cell experiments to be carried out quickly and in parallel on one small device.
Date: September 12, 2007
Summary:
Engineers at Rensselaer Polytechnic Institute have developed tools to help solve two of the main problems slowing the progress of stem cell research -- how to quickly test stem cell response to different drugs or genes, and how to create a large supply of healthy, viable stem cells to study from only a few available cells. The researchers have created methods to study millions of stems cells on devices the size of a standard microscope slide. The techniques enable thousands of individual stem cell experiments to be carried out quickly and in parallel on one small device.
Tuesday, September 11, 2007
Embryonic stem cells are reprogrammed
Source: United Press International
Posted: September 11, 2007 at 4:10 PM EDT
Summary:
U.S. scientists have reported a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state.
Posted: September 11, 2007 at 4:10 PM EDT
Summary:
U.S. scientists have reported a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state.
Customized Virus Kills Brain Tumor Stem Cells That Drive Lethal Cancer
Source: University of Texas M. D. Anderson Cancer Center
Date: September 11, 2007
Summary:
A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.
Date: September 11, 2007
Summary:
A tailored virus destroys brain tumor stem cells that resist other therapies and cause lethal re-growth of cancer after surgery, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the Sept. 18 edition of the Journal of the National Cancer Institute.
Monday, September 10, 2007
Embryonic stem cell strategy advanced with UCSF finding
Source: University of California - San Francisco
Date: September 10, 2007
Summary:
UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells. The scientists developed an alternative to this genetically engineered "switch" technique. They developed serum-free conditions in the cell culture dish that both promoted more successful reprogramming and generated embryonic stem cells that could be detected based on their form and structure, alone.
Date: September 10, 2007
Summary:
UCSF scientists are reporting what they say is a significant improvement in the technique for genetically reprogramming mouse cells to their embryonic state, a process that transforms the cells, in essence, into embryonic stem cells. The scientists developed an alternative to this genetically engineered "switch" technique. They developed serum-free conditions in the cell culture dish that both promoted more successful reprogramming and generated embryonic stem cells that could be detected based on their form and structure, alone.
New Current TV Video: "Stem Cells"
Here is a new video I am featured in with my brother Oliver on Current TV entitled "Stem Cells" that examines the ethical, political, and scientific aspects of stem cell research:
Scientists Eye Secrets of Retinal Regeneration
Source: Weill Cornell Medical College
Date: September 10, 2007
Summary:
Peering at microscopic changes within the retina, scientists in the Department of Ophthalmology at Weill Cornell Medical College in New York City, have discovered a key mechanism driving eye health and eye disease. Reporting in the cover article of a recent edition of Cell, the team says they have discovered just how light-sensing discs in the retina's rod cells regenerate themselves.
Date: September 10, 2007
Summary:
Peering at microscopic changes within the retina, scientists in the Department of Ophthalmology at Weill Cornell Medical College in New York City, have discovered a key mechanism driving eye health and eye disease. Reporting in the cover article of a recent edition of Cell, the team says they have discovered just how light-sensing discs in the retina's rod cells regenerate themselves.
Study: Embryonic stem cells like shaking
Source: United Press International
Posted: September 10, 2007 at 2:49 PM EDT
Summary:
U.S. scientists have discovered embryonic stem cells like to be gently shaken or sloshed, much in the same way they are in a mother's womb. Georgia Institute of Technology and Emory University researchers said such shaking significantly improves embryonic stem cell development and might some day even be used to control what type of cell they eventually become.
Posted: September 10, 2007 at 2:49 PM EDT
Summary:
U.S. scientists have discovered embryonic stem cells like to be gently shaken or sloshed, much in the same way they are in a mother's womb. Georgia Institute of Technology and Emory University researchers said such shaking significantly improves embryonic stem cell development and might some day even be used to control what type of cell they eventually become.
Stem cells better when shaken, scientists say
Source: MSNBC
Posted: September 10, 2007 1:29 p.m. PT
Summary:
"Scientists have known that embryos spend much of their time bobbing along with their mother's movements. So it is perhaps not surprising that researchers have now discovered that embryonic stem cells, which can potentially transform into any kind of body tissue, develop better when their environments are gently jiggled. The finding, detailed in the September issue of the journal Stem Cells, could lead to new ways of controlling what cell type embryonic stem cells ultimately become by moving them in different ways."
Posted: September 10, 2007 1:29 p.m. PT
Summary:
"Scientists have known that embryos spend much of their time bobbing along with their mother's movements. So it is perhaps not surprising that researchers have now discovered that embryonic stem cells, which can potentially transform into any kind of body tissue, develop better when their environments are gently jiggled. The finding, detailed in the September issue of the journal Stem Cells, could lead to new ways of controlling what cell type embryonic stem cells ultimately become by moving them in different ways."
A step toward tissue-engineered heart structures for children
Source: Children's Hospital Boston
Date: September 10, 2007
Summary:
Infants and children receiving artificial heart-valve replacements face several repeat operations as they grow, since the replacements become too small and must be traded for bigger ones. Researchers at Children's Hospital Boston have now developed a solution: living, growing valves created in the lab from a patient's own cells.
Date: September 10, 2007
Summary:
Infants and children receiving artificial heart-valve replacements face several repeat operations as they grow, since the replacements become too small and must be traded for bigger ones. Researchers at Children's Hospital Boston have now developed a solution: living, growing valves created in the lab from a patient's own cells.
Stem cells make new heart valves
Source: Harvard University
Date: September 10, 2007
Summary;
Researchers have coaxed adult stem cells into forming artificial heart valves that could one day mean fewer surgeries for children suffering from heart defects. The scientists, at Harvard-affiliated Boston Children’s Hospital, grew the valves from a type of stem cell that normally gives rise to the inner lining of blood vessels. They used a biodegradable scaffold to give the cells shape and a mix of proteins and growth factors to stimulate the cells to grow into the proper tissue type.
Date: September 10, 2007
Summary;
Researchers have coaxed adult stem cells into forming artificial heart valves that could one day mean fewer surgeries for children suffering from heart defects. The scientists, at Harvard-affiliated Boston Children’s Hospital, grew the valves from a type of stem cell that normally gives rise to the inner lining of blood vessels. They used a biodegradable scaffold to give the cells shape and a mix of proteins and growth factors to stimulate the cells to grow into the proper tissue type.
Embryonic stem cells thrive when shaken
Source: Georgia Institute of Technology
Date: September 10, 2007
Summary:
Embryos spend much of their time in the womb bobbing along with a mother’s movement, and, surprisingly enough, new research from the Georgia Institute of Technology and Emory University suggests that embryonic stem cells may develop much better under similarly shaky conditions.
Date: September 10, 2007
Summary:
Embryos spend much of their time in the womb bobbing along with a mother’s movement, and, surprisingly enough, new research from the Georgia Institute of Technology and Emory University suggests that embryonic stem cells may develop much better under similarly shaky conditions.
Stem cell research leads to key discovery for Fragile X Syndrome
Source: McMaster University
Date: September 10, 2007
Summary:
An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females.
Date: September 10, 2007
Summary:
An important finding has been made by McMaster researchers about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects approximately one in 4,000 males and one in 6,000 females.
Scientists identify stem cells in tendons
Source: United Press International
Posted: Published: September 10, 2007 at 10:28 AM ET
Summary:
U.S. scientists have discovered stem cells in adult tendons can regenerate tissue -- a finding that promises new treatments for tendon injury and disease.
Posted: Published: September 10, 2007 at 10:28 AM ET
Summary:
U.S. scientists have discovered stem cells in adult tendons can regenerate tissue -- a finding that promises new treatments for tendon injury and disease.
USC researcher identifies stem cells in tendons that regenerate tissue in animal model
Source: University of Southern California
Date: September 10, 2007
Summary:
Athletes know that damage to a tendon can signal an end to their professional careers. But a consortium of scientists, led in part by University of Southern California (USC) School of Dentistry researcher Songtao Shi, has identified unique cells within the adult tendon that have stem-cell characteristics—including the ability to proliferate and self-renew. The research team was able to isolate these cells and regenerate tendon-like tissue in the animal model. Their findings hold tremendous promise for the treatment of tendon injuries caused by overuse and trauma.
Date: September 10, 2007
Summary:
Athletes know that damage to a tendon can signal an end to their professional careers. But a consortium of scientists, led in part by University of Southern California (USC) School of Dentistry researcher Songtao Shi, has identified unique cells within the adult tendon that have stem-cell characteristics—including the ability to proliferate and self-renew. The research team was able to isolate these cells and regenerate tendon-like tissue in the animal model. Their findings hold tremendous promise for the treatment of tendon injuries caused by overuse and trauma.
Sunday, September 09, 2007
Researchers Isolate Adult Stem Cells for First Time in Tendon
Source: NIH/National Institute of Dental and Craniofacial Research (NIDCR)
Posted: September 9, 2007 1:00 pm EDT
Summary:
Tendon, the cord-like tissue that connects muscle to bone, contains a small subset of previously unknown adult stem cells, scientists at the National Institute of Dental and Craniofacial Research (NIDCR) part of the National Institutes of Health, and their colleagues have discovered. The finding, published online today in the journal Nature Medicine, points to a natural source of tendon-producing cells in adults and raises the possibility that, with further research, these cells one day could help to mend torn or degenerating tendons that are slow to heal.
Posted: September 9, 2007 1:00 pm EDT
Summary:
Tendon, the cord-like tissue that connects muscle to bone, contains a small subset of previously unknown adult stem cells, scientists at the National Institute of Dental and Craniofacial Research (NIDCR) part of the National Institutes of Health, and their colleagues have discovered. The finding, published online today in the journal Nature Medicine, points to a natural source of tendon-producing cells in adults and raises the possibility that, with further research, these cells one day could help to mend torn or degenerating tendons that are slow to heal.
Friday, September 07, 2007
Systems Biology poised to revolutionise the understanding of cell function and disease
Source: European Science Foundation
Date: September 7, 2007
Summary:
Systems Biology is transforming the way scientists think about biology and disease. This novel approach to research could prompt a shake up in medical science and it might ultimately allow clinicians to predict and treat complex diseases such as diabetes, heart failure, cancer, and metabolic syndrome for which there are currently no cures.
Date: September 7, 2007
Summary:
Systems Biology is transforming the way scientists think about biology and disease. This novel approach to research could prompt a shake up in medical science and it might ultimately allow clinicians to predict and treat complex diseases such as diabetes, heart failure, cancer, and metabolic syndrome for which there are currently no cures.
Thursday, September 06, 2007
University Of Minnesota / U conducts pioneering cellular therapy
Source: Pioneer Press
Posted: September 6, 2007 11:09:11 PM CDT
Summary:
In the world's first clinical trial of its kind, doctors at the University Of Minnesota infused the "T-regulatory" cells into a leukemia patient to see if they protected her, while a separate stem cell transplant repaired her damaged blood and immune systems. Eventually, U researchers want to use the T-reg cells on their own to treat diseases such as Type 1 diabetes and multiple sclerosis that are caused by overaggressive immune systems.
Posted: September 6, 2007 11:09:11 PM CDT
Summary:
In the world's first clinical trial of its kind, doctors at the University Of Minnesota infused the "T-regulatory" cells into a leukemia patient to see if they protected her, while a separate stem cell transplant repaired her damaged blood and immune systems. Eventually, U researchers want to use the T-reg cells on their own to treat diseases such as Type 1 diabetes and multiple sclerosis that are caused by overaggressive immune systems.
UCR Plant Cell Biologist to Study How Plant Stem-Cells Maintain and Change Their Identity
Source: University of California - Riverside
Date: September 6, 2007
Summary:
A plant cell biologist at UC Riverside has received a $1 million grant from the National Science Foundation to investigate how plant stem-cells maintain their identity and how they eventually get specialized into different cell types. According to G. Venugopala Reddy, the principal investigator of the four-year grant, the research, which will focus only on plants, has potential to lead to better insights into how stem cells communicate with each other both before and after they are transformed into specialized cells that lead to the development of different plant organs.
Specifically, Reddy, an assistant professor of plant cell biology who joined UCR’s Department of Botany and Plant Sciences last year, will utilize two powerful methods in his research: microgenomics, which will help identify which genes are active in the stem cells; and live imaging, which will allow him to monitor, in real time, how individual proteins interact in living plant cells. “This research may lead to better insights into stem-cell regulation,” Reddy said.
Date: September 6, 2007
Summary:
A plant cell biologist at UC Riverside has received a $1 million grant from the National Science Foundation to investigate how plant stem-cells maintain their identity and how they eventually get specialized into different cell types. According to G. Venugopala Reddy, the principal investigator of the four-year grant, the research, which will focus only on plants, has potential to lead to better insights into how stem cells communicate with each other both before and after they are transformed into specialized cells that lead to the development of different plant organs.
Specifically, Reddy, an assistant professor of plant cell biology who joined UCR’s Department of Botany and Plant Sciences last year, will utilize two powerful methods in his research: microgenomics, which will help identify which genes are active in the stem cells; and live imaging, which will allow him to monitor, in real time, how individual proteins interact in living plant cells. “This research may lead to better insights into stem-cell regulation,” Reddy said.
Embryonic stem cells used to grow cartilage
Source: Rice University
Date: September 6, 2007
Summary:
Rice University biomedical engineers have developed a new technique for growing cartilage from human embryonic stem cells, a method that could be used to grow replacement cartilage for the surgical repair of knee, jaw, hip, and other joints.
Date: September 6, 2007
Summary:
Rice University biomedical engineers have developed a new technique for growing cartilage from human embryonic stem cells, a method that could be used to grow replacement cartilage for the surgical repair of knee, jaw, hip, and other joints.
Skin stem cells used to mend spines of rats
Source: Toronto Star
Posted: September 6, 2007 04:30 AM EDT
Summary:
The Toronto Star reports researchers have used adult skin stem cells to heal spinal cord injuries in rats:
"Injured rats injected with skin-derived stem cells regained mobility and had better walking co-ordination, according to the study published yesterday in the Journal of Neuroscience. The skin-derived stem cells, injected directly into the injured rats' spinal cords, were able to survive in their new location and set off a flurry of activity, helping to heal the cavity in the cord."
Posted: September 6, 2007 04:30 AM EDT
Summary:
The Toronto Star reports researchers have used adult skin stem cells to heal spinal cord injuries in rats:
"Injured rats injected with skin-derived stem cells regained mobility and had better walking co-ordination, according to the study published yesterday in the Journal of Neuroscience. The skin-derived stem cells, injected directly into the injured rats' spinal cords, were able to survive in their new location and set off a flurry of activity, helping to heal the cavity in the cord."
Wednesday, September 05, 2007
Researchers use skin-derived stem cells to repair spinal cord injuries
Source: The Hospital for Sick Children
Date: September 5, 2007
Summary:
Researchers at The Hospital for Sick Children (SickKids) and the University of British Columbia (UBC) have used skin-derived stem cells to repair spinal cord injuries in rats.
Date: September 5, 2007
Summary:
Researchers at The Hospital for Sick Children (SickKids) and the University of British Columbia (UBC) have used skin-derived stem cells to repair spinal cord injuries in rats.
Specific brain protein required for nerve cell connections to form and function
Source: University of North Carolina at Chapel Hill
Date: September 5, 2007
Summary:
Neurons, or nerve cells, communicate with each other through contact points called synapses. When these connections are damaged, communication breaks down, causing the messages that would normally help our feet push our bike pedals or our mind locate our car keys to fall short. Now scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein called neurexin is required for these nerve cell connections to form and function correctly. The discovery, made in Drosophila fruit flies may lead to advances in understanding autism spectrum disorders, as recently, human neurexins have been identified as a genetic risk factor for autism.
Date: September 5, 2007
Summary:
Neurons, or nerve cells, communicate with each other through contact points called synapses. When these connections are damaged, communication breaks down, causing the messages that would normally help our feet push our bike pedals or our mind locate our car keys to fall short. Now scientists at the University of North Carolina at Chapel Hill School of Medicine have shown that a protein called neurexin is required for these nerve cell connections to form and function correctly. The discovery, made in Drosophila fruit flies may lead to advances in understanding autism spectrum disorders, as recently, human neurexins have been identified as a genetic risk factor for autism.
International Stem Cell Corporation Creates Human Cornea Tissue from Its Parthenote Stem Cells; Preliminary Discovery Holds Promise to Aid in Therapy
Source: International Stem Cell Corporation
Date: September 5, 2007
Summary:
International Stem Cell announced today that data from an independent third party laboratory has confirmed that it has successfully created tissue compatible with a human cornea from embryonic stem cells.
Date: September 5, 2007
Summary:
International Stem Cell announced today that data from an independent third party laboratory has confirmed that it has successfully created tissue compatible with a human cornea from embryonic stem cells.
In Pitt study, muscle stem cells show promise to fight disease
Source: Pittsburgh Post-Gazette
Date: September 5, 2007
Summary:
The Pittsburgh Post-Gazette reports University of Pittsburgh researchers have found new adult muscle stem cells which may lead to new treatments for muscle diseases and injuries:
"Children's Hospital and University of Pittsburgh researchers have identified a group of stem cells derived from adult human muscle that they believe may eventually lead to treatments for such problems as heart attacks and muscular dystrophy."
Dr. Johnny Huard, a professor and vice chairman of research in orthopedic surgery at the University of Pittsburgh School of Medicine lead author of the study, notes dprogress toward a treatment in humans:
"Though much work remains to be done before a treatment could be developed, the findings bring researchers 'much closer to a clinical application of this therapy,"
The story also mentions potential applications of muscle stem cells to treat patients:
"Eventually, researchers hope that muscle biopsies could be obtained from patients with muscle injuries or disease. The myoendothelial cells could be removed and treated in the lab. The stem cells could then be reinjected into the patient to repair the muscle damage."
Date: September 5, 2007
Summary:
The Pittsburgh Post-Gazette reports University of Pittsburgh researchers have found new adult muscle stem cells which may lead to new treatments for muscle diseases and injuries:
"Children's Hospital and University of Pittsburgh researchers have identified a group of stem cells derived from adult human muscle that they believe may eventually lead to treatments for such problems as heart attacks and muscular dystrophy."
Dr. Johnny Huard, a professor and vice chairman of research in orthopedic surgery at the University of Pittsburgh School of Medicine lead author of the study, notes dprogress toward a treatment in humans:
"Though much work remains to be done before a treatment could be developed, the findings bring researchers 'much closer to a clinical application of this therapy,"
The story also mentions potential applications of muscle stem cells to treat patients:
"Eventually, researchers hope that muscle biopsies could be obtained from patients with muscle injuries or disease. The myoendothelial cells could be removed and treated in the lab. The stem cells could then be reinjected into the patient to repair the muscle damage."
Tuesday, September 04, 2007
Neural Stem Cell Study Reveals Mechanism That May Play Role In Cancer
Source: University of California - San Francisco
Date: September 4, 2007
Summary:
In the dynamic world of the developing brain, neural stem cells give rise to neurons deep within the brain’s fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Now, scientists have discovered a key mechanism of this migration – one that may also play an important role in other developmental processes and diseases, including cancer.
Date: September 4, 2007
Summary:
In the dynamic world of the developing brain, neural stem cells give rise to neurons deep within the brain’s fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Now, scientists have discovered a key mechanism of this migration – one that may also play an important role in other developmental processes and diseases, including cancer.
From frogs to humans, brains form the same way
Source: Rockefeller University
Date: September 4, 2007
Summary:
It’s a critical juncture in an embryo’s development: the moment that a brain and nervous system begin to form from a mass of unspecialized cells. Scientists had believed that mammals and amphibians, distinctly different animals, have distinctly different developmental patterns when it comes to the nervous system. But new research suggests that their processes of neural development are actually quite similar.
Date: September 4, 2007
Summary:
It’s a critical juncture in an embryo’s development: the moment that a brain and nervous system begin to form from a mass of unspecialized cells. Scientists had believed that mammals and amphibians, distinctly different animals, have distinctly different developmental patterns when it comes to the nervous system. But new research suggests that their processes of neural development are actually quite similar.
Scientists report major stem cell advance
Source: United Press International
Posted: September 4, 2007 1:31 PM ET
Summary:
U.S. medical scientistshave discovered a group of adult stem cells derived from human muscles that might be used to treat muscle injuries.
Posted: September 4, 2007 1:31 PM ET
Summary:
U.S. medical scientistshave discovered a group of adult stem cells derived from human muscles that might be used to treat muscle injuries.
Pittsburgh scientists identify human source of stem cells with potential to repair muscle
Source: Children's Hospital of Pittsburgh
Date: September 4, 2007
Summary:
For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy. In a study using human muscle tissue, scientists in Children's Stem Cell Research Center isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell-sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cells.
Date: September 4, 2007
Summary:
For the first time, scientists at Children's Hospital of Pittsburgh of UPMC have discovered a unique population of adult stem cells derived from human muscle that could be used to treat muscle injuries and diseases such as heart attack and muscular dystrophy. In a study using human muscle tissue, scientists in Children's Stem Cell Research Center isolated and characterized stem cells taken from blood vessels (known as myoendothelial cells) that are easily isolated using cell-sorting techniques, proliferate rapidly and can be differentiated in the laboratory into muscle, bone and cartilage cells.
Monday, September 03, 2007
Death triggered in cancer-prone intestinal cells
Source: Reuters
Posted: September 3, 2007 6:32AM EDT
Summary:
Researchers in Singapore have worked out a way to kill intestinal stem cells that may develop into colorectal cancer, the second largest cause of cancer related deaths in western countries.
Posted: September 3, 2007 6:32AM EDT
Summary:
Researchers in Singapore have worked out a way to kill intestinal stem cells that may develop into colorectal cancer, the second largest cause of cancer related deaths in western countries.
Stem cell advance offers hope for heart treatments
Source: Agence France Presse (AFP)
Date: September 03, 2007
Summary:
Surgeons will soon be able to literally mend a broken heart using live tissue grown from a patient's very own stem cells, top cardiologists said. The whole procedure -- harvesting cells from bone marrow, growing tissue and surgically implanting the heart muscle or valve -- could take as little as six weeks and could become routine within three-to-five years, they reported.
Another publication of this article can be found here.
Date: September 03, 2007
Summary:
Surgeons will soon be able to literally mend a broken heart using live tissue grown from a patient's very own stem cells, top cardiologists said. The whole procedure -- harvesting cells from bone marrow, growing tissue and surgically implanting the heart muscle or valve -- could take as little as six weeks and could become routine within three-to-five years, they reported.
Another publication of this article can be found here.
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