Saturday, August 27, 2005

Scientists create hybrid cell

Source: Knight Ridder Newspapers
Posted: August 27, 2005 07:50 PM

Summary:

A team of scientists at Harvard have fused skin cells with embryonic stem cells to create a hybrid cell. The new cell can be "reprogrammed" to become a different kind of cell. The new technology may lead to new ways to produce insulin, which could benefit diabetics, regenerate nerves, which could help paralyzed people walk again, and could be used to stave off degenerative diseases such as Parkinson's.

Tuesday, August 23, 2005

Researchers Fuse Skin and Stem Cells

Source: Associated Press
Date: Tuesday, August 23, 2005 18:03 PDT

Summary:

Harvard scientists announced they've discovered a way to fuse adult skin cells with embryonic stem cells, a promising and dramatic breakthrough that could lead to the creation of useful stem cells without first having to create and destroy human embryos.

Step towards making human lungs

Source: BBC NEWS:
Posted: 23 August 2005 10:37:10 GMT

Summary:

Scientists say they have made a significant step towards making human lungs for transplantation. The UK team at Imperial College London took human embryonic stem cells and encouraged them to grow into cells found in adult lungs. In addition to eventually being used to help make whole lungs for transplantation, the cells could also be used to repair parts of damaged lungs.

Monday, August 22, 2005

Microgravity tech could sway stem cell debate

Source: CNET News.com
Posted: August 22, 2005:6:36:51 PDT

Summary:

Microgravity technology developed by NASA can multiply stem cells from a newborn's blood in large enough quantities to be used to regenerate human tissue, London scientists have found. Researchers at U.K.-based Kingston University have discovered in the umbilical cord blood of infants primitive stem cells that are similar to those from human embryos and that can develop into any tissue in the body.

Scientists Find Mechanism for Neural Stem Cell Death

Source: Korea Times
Date: August 22, 2005

Summary:

A team of South Korean scientists has uncovered the mechanism of neural stem cell death, a discovery expected to help treat such degenerative diseases as Parkinson’s and Alzheimer’s.

Scientists Explore New Route for Creating Stem Cells: If successful, the technique could sidestep controversy over embryonic stem cell research

Source: HealthDay News
Date: August 22, 2005

Summary:

Harvard researchers say they've discovered a way to combine embryonic stem cells with human skin cells, which were then reprogrammed to become embryonic cells, hoping that turning adult cells back to their embryonic state would offer new therapeutic possibilities while sidestepping the political concerns of using embryonic stem cells.

Harvard scientists advance cell work: Technique doesn't destroy embryos

Source: Boston Globe
Date: August 22, 2005

Summary:

The Boston Globe reports on a new advance by researchers at Harvard University where human skin cells, when fused with embryonic stem cells, can take on the properties of embryonic stem cells, potentially diffusing the ethical controversy surrounding embryonic stem cell research:

"Harvard scientists have created cells similar to human embryonic stem cells without destroying embryos, a major step toward someday possibly defusing the central objection to stem cell research. The team showed that when a human skin cell was fused with an embryonic stem cell, the resulting hybrid looked and acted like the stem cell. The implications: It may eventually be possible to fashion tailor-made, genetically matched stem cells for patients using such a cell fusion technique, rather than by creating and then destroying a cloned embryo. That use of early embryos is the main sticking point for opponents of stem cell research."

Fusion process advances research on stem cells

Source: USA Today
Posted: August 22, 2005 7:59 AM EDT

Summary:

USA Today reports on the creation of a hybrid stem cell by researchers at Harvard University, an advancement that could diffuse the ethical controversy surrounding embryonic stem cell research:

"Scientists at Harvard Medical School announced that they have created a new kind of hybrid stem cell by fusing skin cells with embryonic stem cells. The advance opens an avenue to creating stem cells without destroying cloned, early-stage embryos or excess embryos from fertility clinics. Because embryonic stem cells are master cells that give rise to all kinds of tissue, scientists see them as a way to cure many diseases. Some social conservatives decry the destruction of human embryos to harvest the cells."

Skin Cells Converted to Stem Cells: Scientists' Work Could Clear Moral Hurdle to Embryonic Research

Source: Washington Post
Date: August 22, 2005

Summary:

The Washington Post reports on the announcement by Harvard University researchers that skin cells have been transformed into cells that appear to have the properties of embryonic stem cells:

"Scientists for the first time have turned ordinary skin cells into what appear to be embryonic stem cells -- without having to use human eggs or make new human embryos a Harvard research team announced yesterday. The technique uses laboratory-grown human embryonic stem cells -- such as the ones that President Bush has already approved for use by federally funded researchers -- to "reprogram" the genes in a person's skin cell, turning that skin cell into an embryonic stem cell itself."

Hybrid hope in stem cell research

Source: BBC News
Posted: 22 August 2005, 16:56 GMT 17:56 UK

Summary:

BBC News reports on a the creation of a hybrid stem cell by Harvard researchers by fusing lab-grown embryonic stem cells with adult cells

"US scientists believe they have found a less controversial way of creating embryonic stem cells by using skin cells to create a 'hybrid" version. The Harvard University team fused lab-grown embryonic stem cells with the adult cells to create the new stem cell, Science will report this week. Researchers believe these hybrid embryonic stem cells could help disease research without using human embryos."

Adult Cells Transformed Into Stem Cells

Source: Harvard University
Posted: August 22, 2005

Summary:

A new type of hybrid cell created at Harvard University could eventually solve the mystery of how embryonic stem cells develop into specialized adult cells, and provide genetically tailored treatments for many human diseases. The technique holds out the possibility of doing this without creating or destroying human embryos. The researchers fused adult skin cells with embryonic stem cells in such a way that the genes of the embryonic cells reset the genetic clock of the adult cells, turning them back to their embryonic form.

Saturday, August 20, 2005

Baby comes with brain repair kit for mum

Source: New Scientist Print Edition
Date: 20 August 2005

Summary:

New Scientist reports on new findings that fetal brain cells may be able to repair brain injury:

"EVERYONE knows that kids get their brains, or lack of them, from their parents. But it now seems that the reverse is also true. Stray stem cells from a growing fetus can colonise the brains of mothers during pregnancy, at least in mice. If the finding is repeated in humans, the medical implications could be profound. Initial results suggest that the fetal cells are summoned to repair damage to the mother's brain. If this is confirmed, it could open up new, safer avenues of treatment for brain damage caused by strokes and Alzheimer's disease."

Friday, August 19, 2005

Growing hope over umbilical-cord stem cells: A promising find could quiet the debate about the cutting-edge field

Source: Houston Chronicle
Posted: August 19, 2005, 12:27 AM

Summary:

The Houston Chronicle reports on new research in which stem cells from umbilical-cord blood might be capable of possess traits of embryonic stem cells:

"A team of Texas and British researchers have produced embryonic-like stem cells from umbilical-cord blood, a breakthrough that could overcome the controversy holding back the cutting-edge field. The researchers reported Thursday that they've grown mass amounts of cord-blood stem cells that have the same ability to turn into any kind of tissue as stem cells taken from human embryos. That ability is considered a key to the future of medicine."

Thursday, August 18, 2005

Shaggy-haired mice aid cell-aging research

Source: San Francisco Chronicle
Date: August 18, 2005

Summary:

Stanford University biologists have created a strain of long-haired laboratory mice that suggest a surprising new role for an enzyme already linked to aging and cancer.

Researchers make 'embryonic-like' stem cells from umbilical cord blood

Source: University of Texas Medical Branch at Galveston
Date: 18 August 2005

Summary:

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities, and provides medical researchers and physicians with an ethical and reliable source of human stem cells for the first time.

Umbilical cord 'stem cell' hope

Source: BBC NEWS:
Posted: 2005/08/18 11:57:46 GMT

Summary:

BBC News reports on a new method of obtaining stem cells from umbilical cord blood using micro-gravity techniques:

"Scientists believe they have found a way to get plentiful stem cells from umbilical cord blood to treat people with diseases.
Stem cells have the potential to turn into many different types of tissue, but using embryonic stem cells is controversial. UK and US team believe they have found a way round this using cord blood and space technology borrowed from NASA. Their microgravity method is described in the journal Cell Proliferation."

Cord blood yields 'ethical' embryonic stem cells

Source: New Scientist
Posted: 18 August 2005 00:01

Summary:

New Scientist reports on the discovery of umbilical cord blood stem cells that may have the therapeutic potential of embryonic stem cells:

"Hopes for treating disease with stem cells from umbilical cord blood has received a major boost, following the discovery of primitive cells with clinical potential matching that of the far more controversial embryonic stem cells (ESCs). The latter are originally derived from human fetuses, which are then destroyed, and have become a major ethical issue, especially in the US."

Alternative to embryo research found

Source: Scotsman.com
Date: Thu 18 August 2005

Summary:

SCIENTISTS have found a way of deriving stem cells from umbilical cords which may end the need to clone human embryos in an attempt to cure diseases.

Wednesday, August 17, 2005

Embryonic-Like Stem Cells Found in Umbilical Cord Blood: If confirmed, the cells could offer way around current ethical issues

Source: University of Texas Medical Branch at Galveston
Date: August 17, 2005

Summary:

A breakthrough in human stem cell research, producing embryonic-like cells from umbilical cord blood may substantially speed up the development of treatments for life-threatening illnesses, injuries and disabilities. The discovery made during a project undertaken with experts from the University of Texas Medical Branch and the Synthecon Corporation in the United States provides medical researchers and physicians with an ethical and reliable source of human stem cells for the first time.

Tuesday, August 16, 2005

Stem cells open the door to greater understanding of neurological diseases

Source: Institute for Stem Cell Research
Date: August 16, 2005

Summary:

Scientists at the Universities of Edinburgh and Milan have developed a new technique to grow pure brain stem cells, which may be used to model diseases of the nervous system and develop new drugs to treat these diseases. The researchers also feel that their work may be a step in the right direction for using stem cells to replace damaged tissue.

Scientists make nerve stem cells

Source: BBC NEWS
Published: 2005/08/16 07:15:23 GMT

Summary:

BBC News reports scientists, for the first time, have created pure nerve cells:

"The world's first pure nerve stem cells made from human embryonic stem cells has been created by scientists at the Universities of Edinburgh and Milan. It is hoped the newly-created cells will eventually help scientists find new treatments for diseases such as Parkinson's and Alzheimer's."

Monday, August 15, 2005

A novel method to propagate stem cells

Source: PLoS Biology
Date: 15 August 2005

Summary:

Scientists have developed a method to propagate mouse brain stem cells derived from ES cells, allowing researchers to culture colonies of mouse brain stem cells that can either propagate without differentiating or become normal brain cells at the flip of a genetic switch.

Gene Controls Stem Cell Differentiation 8/15/05

Source: Bioscience Technology
Date: August 15, 2005

Summary:

A protein known as "TAZ" plays an important role in determining whether adult mesenchymal stem cells (MSCs) found in bone marrow differentiate into bone or fat cells, researchers report. The discovery, they say, may hold promise for treating human diseases ranging from cancer to osteoporosis to childhood obesity.

Gradient Guides Nerve Growth Down Spinal Cord

Source: University of Chicago Medical Center
Date: August 15, 2005

Summary:

The same family of chemical signals that attracts developing sensory nerves up the spinal cord toward the brain serves to repel motor nerves, sending them in the opposite direction, down the cord and away from the brain. The finding may help restore function to people with paralyzing spinal cord injuries.

Monday, August 08, 2005

Compound Can Hasten Harvest of Stem Cells: Mouse study finds chemical speeds movement of cells from bone marrow to bloodstream

Source: HealthDay News
Date: August 8, 2005

Summary:

New insight into how blood-regenerating stem cells travel from bone marrow to the bloodstream is outlined in a study by scientists at the University of Cincinnati and the Cincinnati Children's Hospital Medical Center.

Friday, August 05, 2005

Option to stem cells found: Pitt experts say placental cells offer palatable alternative

Source: Pittsburgh Post-Gazette
Date: August 5, 2005

Summary:

The Pittsburgh Post-Gazette reports on a discovery by researchers at the University of Pittsburgh of a type of cell found in the human placenta that may have characteristics similar to embryonic stem cells:

"University of Pittsburgh researchers have discovered that one type of cell in the human placenta has characteristics that are strikingly similar to embryonic stem cells in their ability to regenerate a wide variety of tissues. The cells, called amniotic epithelial cells, potentially could be used to produce new liver cells to treat liver failure, or new pancreatic islet cells to cure diabetes or new neurons to treat Parkinson's disease."

Discarded Placentas Deliver Researchers Promising Cells Similar To Embryonic Stem Cells

Source: University of Pittsburgh Medical Center
Date: August 5, 2005

Summary:

A University of Pittsburgh study to be published in the journal Stem Cells suggests placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryonic stem cells.

Thursday, August 04, 2005

Stem Cell Transplant Bests Chemo for Common Childhood Leukemia: Five-year survival rates were better than with high-dose chemotherapy, study says

Source: HealthDayNews
Date: Augutst 4, 2005

Summary:

The worst cases of acute lymphoblastic leukemia, the most common leukemia in children, respond better to a stem cell transplant than to chemotherapy, a new study finds.

Tuesday, August 02, 2005

Stem Cell Therapy for Skin Developed

Source: Korea Times
Date: August 2, 2005

Summary:

Skin cells enriched from stem cells are being sprayed on damaged skin to restore the epidermis. A team of Korean scientists has developed a breakthrough technology to heal skin damage, such as burn injuries, by transplanting skin cells enriched from stem cells.

Key to Stem Cell Holy Grail Found

Source: Korea Times
Date: August 2, 2005

Summary:

A Korean husband-and-wife scientist team has made headway in adult stem cell research by discovering a gene in charge of differentiating the parent cells in human bodies.

Monday, August 01, 2005

Experimental therapy could offer new way to treat spine damage

Source: University of Louisville
Date: August 1, 2005

Summary:

An experimental therapy that combines stem cells and gene therapy to repair spinal cord injuries in rats may lead to a new way to treat the same injury in humans. The therapy shows significant potential for repairing the spinal cord by regenerating a protective coating on the nervous system.