Source: Reuters
Posted: November 30, 2007 5:43pm EST
Summary:
Reuters reports researchers have eliminated the cancer risk associated with the recently-reported advance of creating stem cells from skin cells, but that the process is less efficient:
"Researchers who figured out how to make valued embryonic stem cells out of ordinary skin cells said on Friday they had found a way to cut one cancer-causing ingredient out of the mix. But it came at a price -- the method may be safer, but it is also less efficient."
Friday, November 30, 2007
Stem cell breakthrough: Now Japanese team go one better
Source: Agence France Presse (AFP)
Posted: November 30, 2007, 13:57 EST
Summary:
A Japanese team that last week broke new ground in stem cell research announced a further advance on Friday, saying they had made good progress towards clearing a key safety hurdle in their work. In further research, published in the journal Nature Biotechnology, Yamanaka's team report that they can now produce these so-called induced pluripotent stem cells, or iPS cells, without having to resort to a cancer gene found to cause tumours in many of the lab mice in the earlier experiment. If confirmed, it will remove a significant safety hazard in using these cells in transplants one day.
Posted: November 30, 2007, 13:57 EST
Summary:
A Japanese team that last week broke new ground in stem cell research announced a further advance on Friday, saying they had made good progress towards clearing a key safety hurdle in their work. In further research, published in the journal Nature Biotechnology, Yamanaka's team report that they can now produce these so-called induced pluripotent stem cells, or iPS cells, without having to resort to a cancer gene found to cause tumours in many of the lab mice in the earlier experiment. If confirmed, it will remove a significant safety hazard in using these cells in transplants one day.
First Patient Completes StemCells, Inc.'s Phase I Clinical Trial
Source: StemCells, Inc.
Date: November 30, 2007
Summary:
In an official company news release, Stem Cells, Inc., a biotechnology company in the field of stem cell research, announced that the first patient to receive a transplant of purified human neural stem cells in the Company's Phase I clinical trial has completed the trial. The patient, who was transplanted in November 2006, has finished the twelve-month period of immunosuppression and follow-up, and undergone the last of the tests and observations required by the trial protocol. As planned, the patient has subsequently been enrolled in a separate long-term follow-up study, designed to monitor the patients over a four-year period.
Date: November 30, 2007
Summary:
In an official company news release, Stem Cells, Inc., a biotechnology company in the field of stem cell research, announced that the first patient to receive a transplant of purified human neural stem cells in the Company's Phase I clinical trial has completed the trial. The patient, who was transplanted in November 2006, has finished the twelve-month period of immunosuppression and follow-up, and undergone the last of the tests and observations required by the trial protocol. As planned, the patient has subsequently been enrolled in a separate long-term follow-up study, designed to monitor the patients over a four-year period.
Thursday, November 29, 2007
Stanford researchers produce short-term reversal of skin aging in mice
Source: Stanford University
Date: November 29, 2007
Summary:
Researchers at Stanford University have temporarily reversed skin aging on mice by blocking the action of a single protein. The finding may eventually enable older people heal as they did when they were younger. However, Howard Chang, MD, PhD, assistant professor of dermatology and senior author of the study, says the study lead to short-term treatments in older people, but cautions it is not a future fountain of youth. Wired magazine has also published a story on this development.
Date: November 29, 2007
Summary:
Researchers at Stanford University have temporarily reversed skin aging on mice by blocking the action of a single protein. The finding may eventually enable older people heal as they did when they were younger. However, Howard Chang, MD, PhD, assistant professor of dermatology and senior author of the study, says the study lead to short-term treatments in older people, but cautions it is not a future fountain of youth. Wired magazine has also published a story on this development.
Oosight microscope enables embryonic stem cell breakthrough
Source: Marine Biological Laboratory
Date: November 29, 2007
Summary:
A noninvasive, polarized light microscope invented at the Marine Biological Laboratory (MBL) played a crucial role in a recent breakthrough in embryonic stem-cell research aimed at developing medical therapies.
Date: November 29, 2007
Summary:
A noninvasive, polarized light microscope invented at the Marine Biological Laboratory (MBL) played a crucial role in a recent breakthrough in embryonic stem-cell research aimed at developing medical therapies.
Blood stem cells fight invaders, study finds
Source: Harvard Medical School
Date: November 29, 2007
Summary:
New research from Harvard Medical School, published in the November 30 edition of Cell, suggests that the biological role of blood, or hematopoietic stem cells (HSCs) is far more versatile and dynamic. Researchers have found that HSCs can travel from the bone marrow, through the blood system, and enter visceral organs in search of disease-causing invaders, such as bacteria and viruses. Upon encountering an invader they immediately synthesize a defense, divide and mature, producing new immune system cells.
Date: November 29, 2007
Summary:
New research from Harvard Medical School, published in the November 30 edition of Cell, suggests that the biological role of blood, or hematopoietic stem cells (HSCs) is far more versatile and dynamic. Researchers have found that HSCs can travel from the bone marrow, through the blood system, and enter visceral organs in search of disease-causing invaders, such as bacteria and viruses. Upon encountering an invader they immediately synthesize a defense, divide and mature, producing new immune system cells.
Wednesday, November 28, 2007
Researchers identify key genetic trigger of acute myeloid leukemia
Source: St. Jude Children's Research Hospital
Date: November 28, 2007
Summary:
A gene called N-Myc leads a double life in certain white blood cells when it is overexpressed, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.
Date: November 28, 2007
Summary:
A gene called N-Myc leads a double life in certain white blood cells when it is overexpressed, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.
New hope for heart patients after mature cells grown
Source: The Daily Democrat
Posted: November 28, 2007 08:39:03 AM PST
Summary:
The Daily Democrat reports researchers discovered embryonic heart stem cells can be turned into adult heart cells:
"In a new study, UC Davis researchers report the first functional evidence that heart cells from human embryonic stem cells can be converted into adult heart cells. The finding gives scientists hope that these cells can one day be coaxed into becoming viable cells safe for transplant into damaged hearts, potentially avoiding a heart transplant."
Posted: November 28, 2007 08:39:03 AM PST
Summary:
The Daily Democrat reports researchers discovered embryonic heart stem cells can be turned into adult heart cells:
"In a new study, UC Davis researchers report the first functional evidence that heart cells from human embryonic stem cells can be converted into adult heart cells. The finding gives scientists hope that these cells can one day be coaxed into becoming viable cells safe for transplant into damaged hearts, potentially avoiding a heart transplant."
Tuesday, November 27, 2007
Protein Injections Can Delay Symptoms Of Lou Gehrig's Disease
Source: Wake Forest University
Date: November 28, 2007
Summary:
A research team from Wake Forest University School of Medicine is the first to show that injections of a protein normally found in human cells can increase lifespan and delay the onset of symptoms in mice with ALS (amyotrophic lateral sclerosis), or Lou Gehrig's disease. Reporting in the Nov. 28th issue of the Journal of Neuroscience, the researchers said treatments of recombinant heat shock protein 70 (Hsp70) increased total lifespan by 10 percent -- significantly more than Riluzole®, the only ALS treatment approved by the U.S. Food and Drug Administration. They cautioned that while the research suggests a new treatment approach for ALS, it is not ready for studies in patients.
Date: November 28, 2007
Summary:
A research team from Wake Forest University School of Medicine is the first to show that injections of a protein normally found in human cells can increase lifespan and delay the onset of symptoms in mice with ALS (amyotrophic lateral sclerosis), or Lou Gehrig's disease. Reporting in the Nov. 28th issue of the Journal of Neuroscience, the researchers said treatments of recombinant heat shock protein 70 (Hsp70) increased total lifespan by 10 percent -- significantly more than Riluzole®, the only ALS treatment approved by the U.S. Food and Drug Administration. They cautioned that while the research suggests a new treatment approach for ALS, it is not ready for studies in patients.
Stem-cell Therapies For Brain More Complicated Than Thought
Source: Massachusetts Institute of Technology
Date: November 27, 2007
Summary:
An MIT research team’s latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought. In a study published in the Public Library of Science (PloS) Biology on Nov. 13, MIT scientists report that adult stem cells produced in the brain are pre-programmed to make only certain kinds of connections—making it impossible for a neural stem cell originating in the brain to be transplanted to the spinal cord, for instance, to take over functions for damaged cells.
Date: November 27, 2007
Summary:
An MIT research team’s latest finding suggests that stem cell therapies for the brain could be much more complicated than previously thought. In a study published in the Public Library of Science (PloS) Biology on Nov. 13, MIT scientists report that adult stem cells produced in the brain are pre-programmed to make only certain kinds of connections—making it impossible for a neural stem cell originating in the brain to be transplanted to the spinal cord, for instance, to take over functions for damaged cells.
UC DAVIS RESEARCHERS FIND EVIDENCE OF MATURE HEART CELL POTENTIAL IN EMBRYONIC STEM CELLS
Source: University of California - Davis
Date: November 27, 2007
Summary:
In a new study, UC Davis researchers report the first functional evidence that heart cells derived from human embryonic stem cells exhibit one of the most critical properties of mature adult heart cells, an important biological process called excitation-contraction coupling. The finding gives scientists hope that these cells can one day be coaxed into becoming functionally viable cells safe for transplantation into the damaged hearts of patients with end-stage disease, potentially avoiding the necessity of a heart transplant.
Date: November 27, 2007
Summary:
In a new study, UC Davis researchers report the first functional evidence that heart cells derived from human embryonic stem cells exhibit one of the most critical properties of mature adult heart cells, an important biological process called excitation-contraction coupling. The finding gives scientists hope that these cells can one day be coaxed into becoming functionally viable cells safe for transplantation into the damaged hearts of patients with end-stage disease, potentially avoiding the necessity of a heart transplant.
Pluristem's Proprietary PLX Cells Demonstrate Promising Potential in Treating Autoimmune Disorders
Source: Pluristem Therapeutics, Inc.
Posted: November 27, 2007 8:43 am ET
Summary:
Pluristem Therapeutics, Inc., a leading bio-therapeutics Company dedicated to the commercialization of non-personalized (allogeneic) cell therapy products for a variety of malignant, ischemic and autoimmune disorders, announced today that in vitro testing of its PLacenta eXpanded (PLX) cells demonstrated the potential to treat autoimmune disorders.
Posted: November 27, 2007 8:43 am ET
Summary:
Pluristem Therapeutics, Inc., a leading bio-therapeutics Company dedicated to the commercialization of non-personalized (allogeneic) cell therapy products for a variety of malignant, ischemic and autoimmune disorders, announced today that in vitro testing of its PLacenta eXpanded (PLX) cells demonstrated the potential to treat autoimmune disorders.
Monday, November 26, 2007
'Cocktail' of compounds improves brain function in rodents
Source: Massachusetts Institute of Technology
Date: November 26, 2007
Summary:
MIT researchers have shown that a cocktail containing three compounds normally in the blood stream promotes growth of new brain connections and improves cognitive function in rodents. The treatment is now being tested in Alzheimer's patients and could hold promise for other brain diseases and injuries. The mixture, which includes a type of omega-3 fatty acid, is part of a new approach to attacking Alzheimer's. That approach focuses on correcting the loss of synapses, or connections between neurons, which characterizes the disease.
Date: November 26, 2007
Summary:
MIT researchers have shown that a cocktail containing three compounds normally in the blood stream promotes growth of new brain connections and improves cognitive function in rodents. The treatment is now being tested in Alzheimer's patients and could hold promise for other brain diseases and injuries. The mixture, which includes a type of omega-3 fatty acid, is part of a new approach to attacking Alzheimer's. That approach focuses on correcting the loss of synapses, or connections between neurons, which characterizes the disease.
Reprogrammed Skin Cells Could Replace Embryonic Stem Cells
Source: Medical News Today
Article Date: 26 November 2007 - 7:00 PST
Summary:
Medical News Today reports scientists successfully reprogrammed human skin cells to have properties of embryonic stem cells:
"A breakthrough in stem cell research was announced last week in a paper in the journal Science where researchers from the University of Wisconsin -Madison in the US and other colleagues reported how they reprogrammed human skin cells to behave like embryonic stem cells."
Article Date: 26 November 2007 - 7:00 PST
Summary:
Medical News Today reports scientists successfully reprogrammed human skin cells to have properties of embryonic stem cells:
"A breakthrough in stem cell research was announced last week in a paper in the journal Science where researchers from the University of Wisconsin -Madison in the US and other colleagues reported how they reprogrammed human skin cells to behave like embryonic stem cells."
Friday, November 23, 2007
Stem cell hope for immune disease
Source: BBC News
Posted: 23 November 2007, 12:16 GMT
Summary:
BBC News reports bone marrow stem cells may eventually be able to be used to treat immune disorders and autoimmune diseases:
"Common immune system disorders, such as multiple sclerosis and arthritis, could one day be treatable with bone marrow transplants, research suggests. However, currently, the procedure is reserved for life-threatening disorders because chemotherapy or radiotherapy is needed before a transplant can be done. But a protein may do the same job without dangerous side-effects, a mouse study published in Science suggests. The purpose of a bone marrow transplant is to infuse the body with healthy adult stem cells which are able to form fresh blood and immune cells. However, the technique is not yet ready for testing in humans."
Posted: 23 November 2007, 12:16 GMT
Summary:
BBC News reports bone marrow stem cells may eventually be able to be used to treat immune disorders and autoimmune diseases:
"Common immune system disorders, such as multiple sclerosis and arthritis, could one day be treatable with bone marrow transplants, research suggests. However, currently, the procedure is reserved for life-threatening disorders because chemotherapy or radiotherapy is needed before a transplant can be done. But a protein may do the same job without dangerous side-effects, a mouse study published in Science suggests. The purpose of a bone marrow transplant is to infuse the body with healthy adult stem cells which are able to form fresh blood and immune cells. However, the technique is not yet ready for testing in humans."
Wednesday, November 21, 2007
Stem Cell Injection Protects Against Nerve Cell Death After Stroke, Study Suggest
Source: Informscience Agency
Date: November 21, 2007
Summary:
Informscience Agency reports scientists have tested cellular therapy for ischemic stroke on rats. Intravenous transplantation of mesenchymal stem cells was found to restore cerebrum blood supply and protect nerve cells from death.
Date: November 21, 2007
Summary:
Informscience Agency reports scientists have tested cellular therapy for ischemic stroke on rats. Intravenous transplantation of mesenchymal stem cells was found to restore cerebrum blood supply and protect nerve cells from death.
Stem cell transplant can grow new immune system in certain mice
Source: Stanford University
Date: November 21, 2007
Summary:
Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases. The researchers found a way to transplant new blood-forming stem cells into the bone marrow of mice, effectively replacing their immune systems.
Date: November 21, 2007
Summary:
Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases. The researchers found a way to transplant new blood-forming stem cells into the bone marrow of mice, effectively replacing their immune systems.
A mutation named Magellan steers nerve cells off course
Source: Salk Institute for Biological Studies
Date: November 21, 2007
Summary;
Newly launched nerve cells in a growing embryo must chart their course to distant destinations, and many of the means they use to navigate have yet to surface. In a study published in the current issue of the journal Neuron, scientists at the Salk Institute for Biological Studies have recovered a key signal that guides motor neurons – the nascent cells that extend from the spinal cord and must find their way down the length of limbs such as arms, wings and legs.
Date: November 21, 2007
Summary;
Newly launched nerve cells in a growing embryo must chart their course to distant destinations, and many of the means they use to navigate have yet to surface. In a study published in the current issue of the journal Neuron, scientists at the Salk Institute for Biological Studies have recovered a key signal that guides motor neurons – the nascent cells that extend from the spinal cord and must find their way down the length of limbs such as arms, wings and legs.
Stem cells train heart following heart attack
Source: Netherlands Organization for Scientific Research
Date: November 21, 2007
Summary:
Injecting adult stem cells into a heart following a heart attack (infarction) improves the heart function and strengthens the heart wall. A researcher at Leiden University Medical Center used adult human EPDCs that she extracted from the atrium of the heart. She transplanted these cells to a mouse heart that had suffered an infarction. The mice receiving these cells retained a better heart function than mice without these cells, both in the short term and in the longer term of several weeks. The human cells also ensured that less mouse cells died off.
Date: November 21, 2007
Summary:
Injecting adult stem cells into a heart following a heart attack (infarction) improves the heart function and strengthens the heart wall. A researcher at Leiden University Medical Center used adult human EPDCs that she extracted from the atrium of the heart. She transplanted these cells to a mouse heart that had suffered an infarction. The mice receiving these cells retained a better heart function than mice without these cells, both in the short term and in the longer term of several weeks. The human cells also ensured that less mouse cells died off.
Tuesday, November 20, 2007
Scientists Create Embryonic Stem Cells from Skin
Source: NPR
Date: November 20, 2007
Summary;
In a streaming radio broadcast, NPR reports:
"Two teams of scientists have independently discovered a way to turn ordinary human skins cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies."
Date: November 20, 2007
Summary;
In a streaming radio broadcast, NPR reports:
"Two teams of scientists have independently discovered a way to turn ordinary human skins cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies."
UW-Madison scientists guide human skin cells to embryonic state
Source: University of Wisconsin - Madison
Date: November 20, 2007
Summary:
In a paper to be published Nov. 22 in the online edition of the journal Science, a team of University of Wisconsin-Madison researchers reports the genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells. The finding is not only a critical scientific accomplishment, but potentially remakes the tumultuous political and ethical landscape of stem cell biology as human embryos may no longer be needed to obtain the blank slate stem cells capable of becoming any of the 220 types of cells in the human body. Perfected, the new technique would bring stem cells within easy reach of many more scientists as they could be easily made in labs of moderate sophistication, and without the ethical and legal constraints that now hamper their use by scientists.
Date: November 20, 2007
Summary:
In a paper to be published Nov. 22 in the online edition of the journal Science, a team of University of Wisconsin-Madison researchers reports the genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells. The finding is not only a critical scientific accomplishment, but potentially remakes the tumultuous political and ethical landscape of stem cell biology as human embryos may no longer be needed to obtain the blank slate stem cells capable of becoming any of the 220 types of cells in the human body. Perfected, the new technique would bring stem cells within easy reach of many more scientists as they could be easily made in labs of moderate sophistication, and without the ethical and legal constraints that now hamper their use by scientists.
Scientists transform human skin cells into stem cells
Source: Agence France Presse (AFP)
Posted: November 20, 2007, 09:38 EST
Summary:
Two groups of scientists have successfully transformed human skin cells into stem cells, potentially granting unlimited access to the foundation cells which can replace diseased or damaged tissues and organs, it was announced Tuesday. This new technique, once perfected, could eventually allow doctors to create stem cells with a specific patient's genetic code, eliminating the risk of rejection.
Posted: November 20, 2007, 09:38 EST
Summary:
Two groups of scientists have successfully transformed human skin cells into stem cells, potentially granting unlimited access to the foundation cells which can replace diseased or damaged tissues and organs, it was announced Tuesday. This new technique, once perfected, could eventually allow doctors to create stem cells with a specific patient's genetic code, eliminating the risk of rejection.
Monday, November 19, 2007
New technique captures chemical reactions in a single living cell at unprecedented resolution
Source: University of California - Berkeley
Date: November 19, 2007
Summary:
Bioengineers at the University of California, Berkeley, have discovered a technique that for the first time enables the detection of biomolecules' dynamic reactions in a single living cell. The technique, described in the Nov. 18 issue of the journal Nature Methods, could lead to a new era in molecular imaging with implications for cell-based drug discovery and biomedical diagnostics.
Date: November 19, 2007
Summary:
Bioengineers at the University of California, Berkeley, have discovered a technique that for the first time enables the detection of biomolecules' dynamic reactions in a single living cell. The technique, described in the Nov. 18 issue of the journal Nature Methods, could lead to a new era in molecular imaging with implications for cell-based drug discovery and biomedical diagnostics.
MIT IDs proteins key to brain function: Research could lead to new treatments for brain injuries
Source: Massachusetts Institute of Technology
Date: November 19, 2007
Summary:
MIT researchers have identified a family of proteins key to the formation of the communication networks critical for normal brain function. Their research could lead to new treatments for brain injury and disease. The team, led by MIT biology professor Frank Gertler, found that a certain family of proteins is necessary to direct the formation of axons and dendrites, the cellular extensions that facilitate communication between neurons.
Date: November 19, 2007
Summary:
MIT researchers have identified a family of proteins key to the formation of the communication networks critical for normal brain function. Their research could lead to new treatments for brain injury and disease. The team, led by MIT biology professor Frank Gertler, found that a certain family of proteins is necessary to direct the formation of axons and dendrites, the cellular extensions that facilitate communication between neurons.
Friday, November 16, 2007
First Primate Embryonic Stem Cells Cloned By US Scientists
Source: Medical News Today
Article Date: 16 November 2007 - 6:00 PST
Summary:
US scientists have successfully created cloned primate embryos for the first time and used them to make embryonic stem cells. Their work is published in the early online issue of the journal Nature. Researchers at the Oregon National Primate Research Center (ONPRC) based at Oregon Health & Science University (OHSU) in Portland, Oregon, in collaboration with a number of other biomedical research organizations, have successfully produced monkey embryonic stem cells by using a new method to remove the nucleus of the eggs being used.
Article Date: 16 November 2007 - 6:00 PST
Summary:
US scientists have successfully created cloned primate embryos for the first time and used them to make embryonic stem cells. Their work is published in the early online issue of the journal Nature. Researchers at the Oregon National Primate Research Center (ONPRC) based at Oregon Health & Science University (OHSU) in Portland, Oregon, in collaboration with a number of other biomedical research organizations, have successfully produced monkey embryonic stem cells by using a new method to remove the nucleus of the eggs being used.
Thursday, November 15, 2007
'Fingerprints' help find genes involved in differentiation
Source: Baylor College of Medicine
Date: November 15, 2007
Summary:
A database that includes the molecular profiles of the major components of the blood system -- including the stem cells and the cells differentiated from them - enabled researchers at Baylor College of Medicine to identify at least two genes involved in the differentiation process for two different kinds of blood cells.
Date: November 15, 2007
Summary:
A database that includes the molecular profiles of the major components of the blood system -- including the stem cells and the cells differentiated from them - enabled researchers at Baylor College of Medicine to identify at least two genes involved in the differentiation process for two different kinds of blood cells.
Cells Discarded From Womb Lining During A Woman's Period Are New Type Of Stem Cell
Source: BioMed Central
Date: November 15, 2007
Summary:
The cells which thicken the womb wall during a woman's menstrual cycle contain a newly discovered type of stem cell, and could be used in the treatment of damaged and/or old tissue, according to new research. The cells develop into at least 9 different cells including heart, liver and lung at a replication rate much faster than cells which are currently used, taken from umbilical cord blood and bone marrow.
Date: November 15, 2007
Summary:
The cells which thicken the womb wall during a woman's menstrual cycle contain a newly discovered type of stem cell, and could be used in the treatment of damaged and/or old tissue, according to new research. The cells develop into at least 9 different cells including heart, liver and lung at a replication rate much faster than cells which are currently used, taken from umbilical cord blood and bone marrow.
Scientists Reach Breakthrough in Cloning Monkey Embryos
Source: The Online NewsHour
Date: November 15, 2007
Summary:
In a streaming media online broadcast, NewsHour reports scientists say they have extracted embryonic stem cells from cloned monkey embryos. It's the first time that method has been successful with primates.
Date: November 15, 2007
Summary:
In a streaming media online broadcast, NewsHour reports scientists say they have extracted embryonic stem cells from cloned monkey embryos. It's the first time that method has been successful with primates.
Menstrual blood could be rich source of stem cells
Source: New Scientist
Posted: 15 November 2007 13:53
Summary;
New Scientist reports researchers have discovered adult stem cells in menstrual blood that may be able to turn into different human cell types:
"Recent research has indicated that the uterine lining, or endometrium, is a rich source of adult stem cells. But retrieving those cells is as invasive as harvesting adult stem cells from other sources, such as bone marrow. Now two separate groups say they have found these endometrial stem cells in menstrual blood. Both groups say the cells in question show all the hallmarks of stem cells: they replicate themselves without differentiating, they can be made to differentiate into many different cell types under the right conditions, and they show characteristic cell surfaces of stem cells."
Posted: 15 November 2007 13:53
Summary;
New Scientist reports researchers have discovered adult stem cells in menstrual blood that may be able to turn into different human cell types:
"Recent research has indicated that the uterine lining, or endometrium, is a rich source of adult stem cells. But retrieving those cells is as invasive as harvesting adult stem cells from other sources, such as bone marrow. Now two separate groups say they have found these endometrial stem cells in menstrual blood. Both groups say the cells in question show all the hallmarks of stem cells: they replicate themselves without differentiating, they can be made to differentiate into many different cell types under the right conditions, and they show characteristic cell surfaces of stem cells."
Menstrual blood could be a good source of stem cells
Source: CTV.ca, Canada
Date: November 15, 2007
Summary:
A small, recently published study has found that endometrial stem cells are still present in menstrual blood. Xiaolong Meng of the Bio-Communications Research Institute, a private research institute in Wichita, Kansas, has led a team who studied cells taken from the menstrual blood of two women. The researchers were able to develop menstrual blood cells into at least nine different cells, including heart, liver and lung cells.
Date: November 15, 2007
Summary:
A small, recently published study has found that endometrial stem cells are still present in menstrual blood. Xiaolong Meng of the Bio-Communications Research Institute, a private research institute in Wichita, Kansas, has led a team who studied cells taken from the menstrual blood of two women. The researchers were able to develop menstrual blood cells into at least nine different cells, including heart, liver and lung cells.
Brain compensatory mechanisms enhance the recovery from spinal cord injury
Source: National Institute for Physiological Sciences
Date: November 15, 2007
Summary:
A research team led by Tadashi Isa, a professor at the Japanese National Institute for Physiological Sciences, NIPS (SEIRIKEN), and Dr. Yukio Nishimura (University of Washington, Seattle), have found that brain compensatory mechanisms contribute to recovery from spinal cord injury. This study was conducted in collaboration with Hamamatsu Photonics (Dr. Hideo Tsukada) and RIKEN (Dr. Hirotaka Onoe).
Date: November 15, 2007
Summary:
A research team led by Tadashi Isa, a professor at the Japanese National Institute for Physiological Sciences, NIPS (SEIRIKEN), and Dr. Yukio Nishimura (University of Washington, Seattle), have found that brain compensatory mechanisms contribute to recovery from spinal cord injury. This study was conducted in collaboration with Hamamatsu Photonics (Dr. Hideo Tsukada) and RIKEN (Dr. Hirotaka Onoe).
Stem Cell Benefit From Menstruation?
Source: WebMD
November 15, 2007
Summary:
WebMD reports menstrual blood may be a source of adult stem cells that can become multiple types of human cells:
"Menstruation may have a fringe benefit as a source of adult stem cells. Scientists report that menstrual blood contains adult stem cells that can develop into nine different types of cells: heart cells, lung cells, nerve cells, muscle cells, cells that line the inside of blood vessels, pancreatic cells, liver cells, fat cells, bone cells."
November 15, 2007
Summary:
WebMD reports menstrual blood may be a source of adult stem cells that can become multiple types of human cells:
"Menstruation may have a fringe benefit as a source of adult stem cells. Scientists report that menstrual blood contains adult stem cells that can develop into nine different types of cells: heart cells, lung cells, nerve cells, muscle cells, cells that line the inside of blood vessels, pancreatic cells, liver cells, fat cells, bone cells."
Researcher Programs Mouse Embryonic Stem Cells to Develop into Tissues Resembling Human Skin
Source: St. John's University
Date: November 15, 2007
Summary:
Researchers at St. John's University have discovered that mouse embryonic stem cells, when artificially manipulated, have the capacity to transform into intact biomembranes, or cell tissues, while other normal and cancerous human cells do not. Specifically, the researchers believe they have found a way to chemically ‘program’ mouse stem cells to develop into tissues resembling human skin cells and certain membranous stomach cells, such as those found in organs like the large and small intestines.
Date: November 15, 2007
Summary:
Researchers at St. John's University have discovered that mouse embryonic stem cells, when artificially manipulated, have the capacity to transform into intact biomembranes, or cell tissues, while other normal and cancerous human cells do not. Specifically, the researchers believe they have found a way to chemically ‘program’ mouse stem cells to develop into tissues resembling human skin cells and certain membranous stomach cells, such as those found in organs like the large and small intestines.
Medistem Announces Discovery of Novel Stem Cell Population in Menstrual Blood: Endometrial Regenerative Cells (ERC)
Source: Medistem Laboratories
Posted: November 15, 2007 09:30 ET
Summary:
Medistem Laboratories, Inc. in collaboration with researchers from the University of Western Ontario, University of Alberta, and the Bio-Communications Research Institute, has published a paper describing a novel stem cell population derived from menstrual blood. The publication, entitled "Endometrial Regenerative Cells: A Novel Stem Cell Population" appeared in today's Journal of Translational Medicine.
Posted: November 15, 2007 09:30 ET
Summary:
Medistem Laboratories, Inc. in collaboration with researchers from the University of Western Ontario, University of Alberta, and the Bio-Communications Research Institute, has published a paper describing a novel stem cell population derived from menstrual blood. The publication, entitled "Endometrial Regenerative Cells: A Novel Stem Cell Population" appeared in today's Journal of Translational Medicine.
New type of stem cell from menstrual blood
Source: United Press International
Posted: November 15, 2007 at 11:14 AM EST
Summary:
A team of U.S. and Canadian researchers have identified a new type of stem cell that can be isolated from menstrual blood of healthy women.
Posted: November 15, 2007 at 11:14 AM EST
Summary:
A team of U.S. and Canadian researchers have identified a new type of stem cell that can be isolated from menstrual blood of healthy women.
Clones of monkey embryos raise hopes for stem cell research
Source: San Francisco Chronicle
Date: November 15, 2007
Summary:
Researchers revealed that they have successfully cloned embryos of rhesus monkeys and obtained stem cells from them that could be turned into heart and nerve tissue - a laboratory breakthrough that could one day lead to similar work in human beings. The study renews the belief, previously dashed by fraud, that a similar process using cloned human embryos could create transplant tissue genetically matched to patients, thus avoiding the risk of rejection.
Date: November 15, 2007
Summary:
Researchers revealed that they have successfully cloned embryos of rhesus monkeys and obtained stem cells from them that could be turned into heart and nerve tissue - a laboratory breakthrough that could one day lead to similar work in human beings. The study renews the belief, previously dashed by fraud, that a similar process using cloned human embryos could create transplant tissue genetically matched to patients, thus avoiding the risk of rejection.
Scientists Use Monkey Clones to Extract Stem Cells
Source: New York Times
Date: November 15, 2007
Summary:
The New York Times reports researchers have obtained stem cells from cloned monkey embryos:
"Researchers in Oregon are reporting that they used cloning to produce monkey embryos and then extracted stem cells from the embryos."
The story mentions this new discovery could eventually be applied to treat human medical conditions:
"Not only is this the first time such cells have been produced in any animal other than a mouse, but the method, the researchers say, should also work in humans. In 2004, South Korean researchers reported making stem cells from cloned human embryos, but the claim turned out fraudulent."
The study's lead author believes this new cloning technique could also be used to produce human embryonic stem cells:
'We hope the technology will be useful for other labs that are working on human eggs and human cells,” the lead researcher of the group, Shoukhrat Mitalipov at Oregon Health and Science University in Beaverton, said in a telephone interview. “I am quite sure it will work in humans.'”
Date: November 15, 2007
Summary:
The New York Times reports researchers have obtained stem cells from cloned monkey embryos:
"Researchers in Oregon are reporting that they used cloning to produce monkey embryos and then extracted stem cells from the embryos."
The story mentions this new discovery could eventually be applied to treat human medical conditions:
"Not only is this the first time such cells have been produced in any animal other than a mouse, but the method, the researchers say, should also work in humans. In 2004, South Korean researchers reported making stem cells from cloned human embryos, but the claim turned out fraudulent."
The study's lead author believes this new cloning technique could also be used to produce human embryonic stem cells:
'We hope the technology will be useful for other labs that are working on human eggs and human cells,” the lead researcher of the group, Shoukhrat Mitalipov at Oregon Health and Science University in Beaverton, said in a telephone interview. “I am quite sure it will work in humans.'”
Wednesday, November 14, 2007
Monkey embryos cloned in stem cell first
Source: Financial Times
Published: November 15 2007 04:31 | Last updated: November 15 2007 04:31
Summary:
The Financial Times reports researchers derived stem cells from cloned monkey embryos:
"Scientists in the US have for the first time made cloned embryos from adult monkeys and extracted stem cells from them. The success, published online by the journal Nature, will encourage researchers who want to create cloned human embryos for stem cell experiments."
Published: November 15 2007 04:31 | Last updated: November 15 2007 04:31
Summary:
The Financial Times reports researchers derived stem cells from cloned monkey embryos:
"Scientists in the US have for the first time made cloned embryos from adult monkeys and extracted stem cells from them. The success, published online by the journal Nature, will encourage researchers who want to create cloned human embryos for stem cell experiments."
Stem-Cell Researchers Clone Monkey Embryo
Source: NPR
Date: November 14, 2007
Summary:
In a streaming radio broadcast, National Public Radio (NPR) reports scientists have cloned a money embryo:
" Scientists have announced another first in cloning: They have cloned a primate embryo. The researchers in Oregon say they used those cloned monkey embryos to derive embryonic stem cells. Researchers hope to one day use such a process in humans to create customized stem-cell therapies for individual patients."
Date: November 14, 2007
Summary:
In a streaming radio broadcast, National Public Radio (NPR) reports scientists have cloned a money embryo:
" Scientists have announced another first in cloning: They have cloned a primate embryo. The researchers in Oregon say they used those cloned monkey embryos to derive embryonic stem cells. Researchers hope to one day use such a process in humans to create customized stem-cell therapies for individual patients."
Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
Source: Cell Press
Date: November 14, 2007
Summary:
Science Daily summarizes a Cell Press report that a human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
Date: November 14, 2007
Summary:
Science Daily summarizes a Cell Press report that a human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
Researchers clone monkeys for stem cells
Source: Reuters
Posted: November 14, 2007 1:02pm ET
Summary:
Reuters reports researchers have derived stem cells from cloned monkey embryos:
"U.S. researchers have cloned monkeys and used the resulting embryos to get valued embryonic stem cells, an important step towards being able to do the same thing in humans, they reported on Wednesday. Shoukhrat Mitalipov and colleagues at Oregon Health & Science University said they used skin cells from monkeys to create cloned embryos, and then extracted embryonic stem cells from these days-old embryos."
Posted: November 14, 2007 1:02pm ET
Summary:
Reuters reports researchers have derived stem cells from cloned monkey embryos:
"U.S. researchers have cloned monkeys and used the resulting embryos to get valued embryonic stem cells, an important step towards being able to do the same thing in humans, they reported on Wednesday. Shoukhrat Mitalipov and colleagues at Oregon Health & Science University said they used skin cells from monkeys to create cloned embryos, and then extracted embryonic stem cells from these days-old embryos."
OHSU Scientists First To Successfully Create Primate Embryonic Stem Cells
Source: Oregon Health & Science University
Date: November 14, 2007
Summary:
Researchers at Oregon Health & Science University’s Oregon National Primate Research Center have made a significant breakthrough in efforts to develop human stem cell therapies that may be used to combat numerous devastating diseases. For the first time, scientists have successfully derived embryonic stem cells by reprogramming of genetic material from skin cells while studying rhesus macaque monkeys. The breakthrough follows several previously unsuccessful attempts by the OHSU-based team and other scientific teams worldwide. The results of the work were released online today by the scientific journal Nature. The work will also be published in next week’s edition of the journal.
Date: November 14, 2007
Summary:
Researchers at Oregon Health & Science University’s Oregon National Primate Research Center have made a significant breakthrough in efforts to develop human stem cell therapies that may be used to combat numerous devastating diseases. For the first time, scientists have successfully derived embryonic stem cells by reprogramming of genetic material from skin cells while studying rhesus macaque monkeys. The breakthrough follows several previously unsuccessful attempts by the OHSU-based team and other scientific teams worldwide. The results of the work were released online today by the scientific journal Nature. The work will also be published in next week’s edition of the journal.
Cloned monkey stem cells produced: Stem cells extracted from cloned primate embryos.
Source: Nature
Published online 14 November 2007
Summary:
Researchers have for the first time created cloned primate embryos and used them to make embryonic stem-cell lines. The achievement has led to speculation about when similar success in humans might open up the door for therapeutic cloning.
Published online 14 November 2007
Summary:
Researchers have for the first time created cloned primate embryos and used them to make embryonic stem-cell lines. The achievement has led to speculation about when similar success in humans might open up the door for therapeutic cloning.
Tuesday, November 13, 2007
A first: Stem cell lines made from embryos of primates
Source: USA Today
Date: November 13, 2007
Summary:
USA Today reports Oregon scientists have created embryonic stem cell lines from cloned monkey embryos:
"Scientists in Oregon have successfully cloned monkey embryos and used them to make two embryonic stem cell lines. It is the first time this has been accomplished in primates and brings the possibility of human stem cell lines one step closer to reality.
Researchers at Oregon Health and Science University in Portland removed the DNA from a rhesus macaque egg and replaced it with genetic material from a different macaque's skin cell. The two were fused with electricity. After five to seven days, this early-stage embryo was destroyed to harvest the stem cells."
Date: November 13, 2007
Summary:
USA Today reports Oregon scientists have created embryonic stem cell lines from cloned monkey embryos:
"Scientists in Oregon have successfully cloned monkey embryos and used them to make two embryonic stem cell lines. It is the first time this has been accomplished in primates and brings the possibility of human stem cell lines one step closer to reality.
Researchers at Oregon Health and Science University in Portland removed the DNA from a rhesus macaque egg and replaced it with genetic material from a different macaque's skin cell. The two were fused with electricity. After five to seven days, this early-stage embryo was destroyed to harvest the stem cells."
Scientists claim to clone monkey embryos, potential boon for stem cell research
Source: Associated Press
Posted: November 13, 2007 2:39 p.m. PST
Summary:
The Associated Press reports on the derivation of stem cells from cloned monkey embryos:
"Scientists in Oregon say they've reached the long-sought goal of cloning monkey embryos and extracting stem cells from them, a potentially major step toward doing the same thing in people. The research has not been published yet or confirmed by other scientists. But if true, it offers fresh hope in field that has been marked by frustration and even fraud. The claim of a similar breakthrough with human embryos by a South Korean scientist in 2004 turned out to be false. The hope is that one day, such a procedure could be used to create transplant tissue that's genetically matched to an ailing patient. Because stem cells can form all types of tissue, the approach might one day help treat conditions like diabetes and spinal cord injury without fear of rejection by the patient's body."
Posted: November 13, 2007 2:39 p.m. PST
Summary:
The Associated Press reports on the derivation of stem cells from cloned monkey embryos:
"Scientists in Oregon say they've reached the long-sought goal of cloning monkey embryos and extracting stem cells from them, a potentially major step toward doing the same thing in people. The research has not been published yet or confirmed by other scientists. But if true, it offers fresh hope in field that has been marked by frustration and even fraud. The claim of a similar breakthrough with human embryos by a South Korean scientist in 2004 turned out to be false. The hope is that one day, such a procedure could be used to create transplant tissue that's genetically matched to an ailing patient. Because stem cells can form all types of tissue, the approach might one day help treat conditions like diabetes and spinal cord injury without fear of rejection by the patient's body."
GERON’S HUMAN EMBRYONIC STEM CELL-BASED THERAPEUTIC FOR SPINAL CORD INJURY EVADES DIRECT ATTACK BY HUMAN IMMUNE SYSTEM
Source: Geron Corporation
Date: November 13, 2007
Summary:
In an official company news release, Geron Corporation, a biotechnology company in the field of stem cell research, reported its embryonic stem cell therapy to treat spinal cord injury evaded attack by the immune system:
"Geron Corporation today announced the publication of study results showing that GRNOPC1, the company's human embryonic stem cell (hESC)-based therapeutic for the treatment of spinal cord injury, evades direct attack by the human immune system in vitro. Published in the November online issue of the Journal of Neuroimmunology, the results of research conducted by Ross Okamura, Ph.D. and other Geron scientists suggest that unlike whole organ transplants, cellular therapeutics derived from hESCs may provoke only minimal immune reactions and that rejection may be controlled or prevented by short courses of low-dose immunosuppressive drugs. The results also support the position that patient-specific hESC lines are not needed to prevent immune rejection."
Date: November 13, 2007
Summary:
In an official company news release, Geron Corporation, a biotechnology company in the field of stem cell research, reported its embryonic stem cell therapy to treat spinal cord injury evaded attack by the immune system:
"Geron Corporation today announced the publication of study results showing that GRNOPC1, the company's human embryonic stem cell (hESC)-based therapeutic for the treatment of spinal cord injury, evades direct attack by the human immune system in vitro. Published in the November online issue of the Journal of Neuroimmunology, the results of research conducted by Ross Okamura, Ph.D. and other Geron scientists suggest that unlike whole organ transplants, cellular therapeutics derived from hESCs may provoke only minimal immune reactions and that rejection may be controlled or prevented by short courses of low-dose immunosuppressive drugs. The results also support the position that patient-specific hESC lines are not needed to prevent immune rejection."
Scientists discover stem cell cue: Hope to regenerate injured spinal cords
Source: Montreal Gazette
Date: November 13, 2007
Summary:
The Montreal Gazette reports researchers have discovered a protein to guide embryonic stem cells in order to repair injured spinal cords in mice:
"Montreal researchers have identified what might be a pivotal first step toward regenerating injured spinal cords using the body's own stem cells. The repair mechanism that works well in developing our embryonic nervous system seems to work in reverse in adults following injury, explained neuroscientist Tim Kennedy of the Montreal Neurological Institute. The mechanism involves a protein that acts like a guidance cue for directing embryonic cells."
Date: November 13, 2007
Summary:
The Montreal Gazette reports researchers have discovered a protein to guide embryonic stem cells in order to repair injured spinal cords in mice:
"Montreal researchers have identified what might be a pivotal first step toward regenerating injured spinal cords using the body's own stem cells. The repair mechanism that works well in developing our embryonic nervous system seems to work in reverse in adults following injury, explained neuroscientist Tim Kennedy of the Montreal Neurological Institute. The mechanism involves a protein that acts like a guidance cue for directing embryonic cells."
Monday, November 12, 2007
Developing Drugs To Limit Massive Cell Death After Spinal Cord Injury
Source: Helmholtz Association
Date: November 12, 2007
Summary:
Neurons die 'en masse' when the spinal cord is injured or when a person suffers a stroke. Researchers have now unraveled the molecular mechanism which causes the death not only of damaged neurons, but also of healthy nerve cells. In animal experiments, they have now been able to demonstrate that neuronal cell death can be reduced when the gene of one the key players in this process is knocked out.
Date: November 12, 2007
Summary:
Neurons die 'en masse' when the spinal cord is injured or when a person suffers a stroke. Researchers have now unraveled the molecular mechanism which causes the death not only of damaged neurons, but also of healthy nerve cells. In animal experiments, they have now been able to demonstrate that neuronal cell death can be reduced when the gene of one the key players in this process is knocked out.
Cancer Gene Drives Pivotal Decision In Early Brain Development
Source: Washington University in St. Louis
Date: November 12, 2007
Summary:
A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers have found. The study reveals that the neurofibromatosis 1 (NF1) gene helps push stem cells down separate paths that lead them to become two major types of brain cells: support cells known as astrocytes and brain neurons.
Date: November 12, 2007
Summary:
A gene linked to pediatric brain tumors is an essential driver of early brain development, researchers have found. The study reveals that the neurofibromatosis 1 (NF1) gene helps push stem cells down separate paths that lead them to become two major types of brain cells: support cells known as astrocytes and brain neurons.
Researchers take first steps towards spinal cord reconstruction following injury
Source: Montreal Neurological Institute and Hospital
Date: November 12, 2007
Summary:
A new study by researchers at McGill University's Montreal Neurological Institute and Hospital has identified what may be a pivotal first step towards the regeneration of nerve cells following spinal cord injury, using the body's own stem cells. This seminal study, published in this week's Proceedings of the National Academy of Science, identifies key elements in the body's reaction to spinal injury, critical information that could lead to novel therapies for repairing previously irreversible nerve damage in the injured spinal cord.
Date: November 12, 2007
Summary:
A new study by researchers at McGill University's Montreal Neurological Institute and Hospital has identified what may be a pivotal first step towards the regeneration of nerve cells following spinal cord injury, using the body's own stem cells. This seminal study, published in this week's Proceedings of the National Academy of Science, identifies key elements in the body's reaction to spinal injury, critical information that could lead to novel therapies for repairing previously irreversible nerve damage in the injured spinal cord.
VistaGen Publishes Preclinical Data Supporting the Therapeutic Potential of AV-101 for Parkinson's Disease
Source: VistaGen Therapeutics, Inc.
Posted: November 12, 2007 8:30 am ET
Summary:
VistaGen Therapeutics, Inc. announced publication of preclinical data suggesting that AV-101, its lead drug candidate for treatment of neurological disorders, may be useful for treating Parkinson's disease.
Posted: November 12, 2007 8:30 am ET
Summary:
VistaGen Therapeutics, Inc. announced publication of preclinical data suggesting that AV-101, its lead drug candidate for treatment of neurological disorders, may be useful for treating Parkinson's disease.
Friday, November 09, 2007
The Birth of a Brain Cell: Scientists Witness Neurogenesis
Source: Scientific American
Date: November 9, 2007
Summary:
Scientific American reports scientists have discovered a new way to track and view stem cells in the brains of animals, including humans:
"For the first time, researchers have developed a way to view stem cells in the brains of living animals, including humans—a finding that allows scientists to follow the process neurogenesis (the birth of neurons). The discovery comes just months after scientists confirmed that such cells are generated in adult as well as developing brains."
Date: November 9, 2007
Summary:
Scientific American reports scientists have discovered a new way to track and view stem cells in the brains of animals, including humans:
"For the first time, researchers have developed a way to view stem cells in the brains of living animals, including humans—a finding that allows scientists to follow the process neurogenesis (the birth of neurons). The discovery comes just months after scientists confirmed that such cells are generated in adult as well as developing brains."
Thursday, November 08, 2007
Scientists Find Way to Track Stem Cells in Brain
Source: HealthDay News
Date: November 8, 2007
Summary:
HealthDay News reports researchers have discovered a new genetic marker that is enabling them to track stem cells in the brain:
"The identification of a new marker is making it possible to track brain stem cells for the first time, U.S. researchers report. The achievement is already opening doors to new research into depression, early childhood development and multiple sclerosis, the team's senior author said. The study was funded by U.S. National Institutes of Health and is published in the Nov. 9 issue of Science."
Date: November 8, 2007
Summary:
HealthDay News reports researchers have discovered a new genetic marker that is enabling them to track stem cells in the brain:
"The identification of a new marker is making it possible to track brain stem cells for the first time, U.S. researchers report. The achievement is already opening doors to new research into depression, early childhood development and multiple sclerosis, the team's senior author said. The study was funded by U.S. National Institutes of Health and is published in the Nov. 9 issue of Science."
Imaging neural progenitor cells in the living human brain
Source: National Institute of Neurological Disorders and Stroke
Date: November 8, 2007
Summary:
For the first time, investigators have identified a way to detect neural progenitor cells (NPCs), which can develop into neurons and other nervous system cells, in the living human brain using a type of imaging called magnetic resonance spectroscopy (MRS). The finding, supported by the National Institutes of Health (NIH), may lead to improved diagnosis and treatment for depression, Parkinson's disease, brain tumors, and a host of other disorders.
Date: November 8, 2007
Summary:
For the first time, investigators have identified a way to detect neural progenitor cells (NPCs), which can develop into neurons and other nervous system cells, in the living human brain using a type of imaging called magnetic resonance spectroscopy (MRS). The finding, supported by the National Institutes of Health (NIH), may lead to improved diagnosis and treatment for depression, Parkinson's disease, brain tumors, and a host of other disorders.
SBUMC Researchers First To Image A Biomarker Of Neurogenesis; Finding May Impact Treatment of MS, Depression, Other Diseases
Source: Stony Brook University
Date: November 8, 2007
Summary:
Mirjana Maletic-Savatic, M.D., Ph.D., and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain. This discovery allows researchers to monitor neurogenesis, the development of nerve tissues. The finding may also prove to be monumental in the diagnosis and treatment of multiple sclerosis, Parkinson’s disease, depression, and other disorders of the central nervous system where neurogenesis is disrupted. The investigators are the first in the world to detect NPCs in this way. Their findings are published in the November 9 issue of the journal Science.
Date: November 8, 2007
Summary:
Mirjana Maletic-Savatic, M.D., Ph.D., and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain. This discovery allows researchers to monitor neurogenesis, the development of nerve tissues. The finding may also prove to be monumental in the diagnosis and treatment of multiple sclerosis, Parkinson’s disease, depression, and other disorders of the central nervous system where neurogenesis is disrupted. The investigators are the first in the world to detect NPCs in this way. Their findings are published in the November 9 issue of the journal Science.
Scientists develop non-invasive method to track nerve-cell development in live human brain
Source: Cold Spring Harbor Laboratory
Date: November 8, 2007
Summary:
A team of scientists including researchers at Cold Spring Harbor Laboratory (CSHL) have identified and validated the first biomarker that permits neural stem and progenitor cells (NPCs) to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders.
Date: November 8, 2007
Summary:
A team of scientists including researchers at Cold Spring Harbor Laboratory (CSHL) have identified and validated the first biomarker that permits neural stem and progenitor cells (NPCs) to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders.
Adult brain cells are movers and shakers
Source: Johns Hopkins Medical Institutions
Date: November 8, 2007
Summary:
It’s a general belief that the circuitry of young brains has robust flexibility but eventually gets “hard-wired” in adulthood. As Johns Hopkins researchers and their colleagues report in the Nov. 8 issue of Neuron, however, adult neurons aren’t quite as rigidly glued in place as we suspect.
Date: November 8, 2007
Summary:
It’s a general belief that the circuitry of young brains has robust flexibility but eventually gets “hard-wired” in adulthood. As Johns Hopkins researchers and their colleagues report in the Nov. 8 issue of Neuron, however, adult neurons aren’t quite as rigidly glued in place as we suspect.
Seaweed Transformed Into Stem Cell Technology
Source: Rensselaer Polytechnic Institute (RPI)
Date: November 8, 2007
Summary:
Engineers at Rensselaer Polytechnic Institute have transformed a polymer found in common brown seaweed into a device that can support the growth and release of stem cells at the sight of a bodily injury or at the source of a disease. The findings, which are detailed in the December 2007 edition of Biomaterials, mark an important step in efforts to develop new medical therapies using stem cells.
Date: November 8, 2007
Summary:
Engineers at Rensselaer Polytechnic Institute have transformed a polymer found in common brown seaweed into a device that can support the growth and release of stem cells at the sight of a bodily injury or at the source of a disease. The findings, which are detailed in the December 2007 edition of Biomaterials, mark an important step in efforts to develop new medical therapies using stem cells.
Progress toward new therapies for coronary artery disease
Source: Burnham Institute for Medical Research
Date: November 7, 2007
Summary:
Coronary artery disease is a leading cause of mortality in Western countries. It cannot be cured. Recent research, led by Pilar Ruiz-Lozano, Ph.D., at the Burnham Institute for Medical Research, may lead to new therapies for coronary artery disease. The research demonstrated that stimulation of the Wnt signaling pathway is essential for the formation of the coronary vasculature. The Wnt pathways of secreted factors has been known previously to play a role in embryogenesis and development, and it also functions as a regulator of some stem cell populations.
Date: November 7, 2007
Summary:
Coronary artery disease is a leading cause of mortality in Western countries. It cannot be cured. Recent research, led by Pilar Ruiz-Lozano, Ph.D., at the Burnham Institute for Medical Research, may lead to new therapies for coronary artery disease. The research demonstrated that stimulation of the Wnt signaling pathway is essential for the formation of the coronary vasculature. The Wnt pathways of secreted factors has been known previously to play a role in embryogenesis and development, and it also functions as a regulator of some stem cell populations.
Stem cell find for child cancer
Source: BBC News
Posted: 8 November 2007, 12:47 GMT
Summary:
BBC News reports on the discovery of a type of stem cell in dogs that enable new cancer treatments:
"Scientists have uncovered a stem cell in dogs which could lead to new treatments for bone cancer in children. The cancer stem cell makes copies of the disease, enabling it to spread around the body. It appears notoriously resistant to treatment. But by identifying it, it may be possible to work out how to target it."
Posted: 8 November 2007, 12:47 GMT
Summary:
BBC News reports on the discovery of a type of stem cell in dogs that enable new cancer treatments:
"Scientists have uncovered a stem cell in dogs which could lead to new treatments for bone cancer in children. The cancer stem cell makes copies of the disease, enabling it to spread around the body. It appears notoriously resistant to treatment. But by identifying it, it may be possible to work out how to target it."
Wednesday, November 07, 2007
Stem cell hope for Alzheimer's
Source: Daily Telegraph
Posted: Last Updated: 12:01am GMT 08/11/2007
Summary:
The Daily Telegraph reports researchers believe stem cells could restore memory in people with brain injuries and diseases:
"Stroke victims and Alzheimer's patients could have their memories repaired through stem cell therapy, scientists say. Researchers believe their research opens up the possibility of new brain cells being grown to reverse memory loss in millions of people who suffer from dementia and brain injuries. Tests showed stem cells, the body's basic building blocks used for repair and growth, can turn into new brain cells and produce a chemical that protects existing damaged ones."
Posted: Last Updated: 12:01am GMT 08/11/2007
Summary:
The Daily Telegraph reports researchers believe stem cells could restore memory in people with brain injuries and diseases:
"Stroke victims and Alzheimer's patients could have their memories repaired through stem cell therapy, scientists say. Researchers believe their research opens up the possibility of new brain cells being grown to reverse memory loss in millions of people who suffer from dementia and brain injuries. Tests showed stem cells, the body's basic building blocks used for repair and growth, can turn into new brain cells and produce a chemical that protects existing damaged ones."
Stem cells 'may reverse Alzheimer's symptoms'
Source: Evening Standard
Date: 8 November 2007
Summary:
The Evening Standard reports scientists have used stem cells to treat memory loss using adult stem cells:
"Scientists have moved a crucial step towards reversing symptoms of Alzheimer's disease by using stem cells. In a breakthrough bringing hope to millions, the cells repaired damaged parts of the brain and restored lost memory. It is the first time that stem cells have been shown to reverse the type of memory problems associated with strokes, Alzheimer's and degenerative brain diseases."
Date: 8 November 2007
Summary:
The Evening Standard reports scientists have used stem cells to treat memory loss using adult stem cells:
"Scientists have moved a crucial step towards reversing symptoms of Alzheimer's disease by using stem cells. In a breakthrough bringing hope to millions, the cells repaired damaged parts of the brain and restored lost memory. It is the first time that stem cells have been shown to reverse the type of memory problems associated with strokes, Alzheimer's and degenerative brain diseases."
Stem cells offer hope of Alzheimer's cure
Source: The Scotsman
Date: 8 November 2007
Summary:
The Scotsman reports scientists have used neural stem cells to reverse memory loss in mice, which could lead to effective treatments for Alzheimer's Disease:
"BRAIN diseases such as Alzheimer's and strokes could be treated by stem-cell therapy, a study suggests. Scientists have used the technique to repair the damaged memory of mice - and believe it could work in humans. US researchers injected neural stem cells into the brains of mice and after three months they seemed to have matured and made the right connections to reverse the memory deficit. The experiments provide the first evidence that stem cells could reverse cognitive damage lost through strokes, Alzheimer's and other neurodegenerative diseases."
Date: 8 November 2007
Summary:
The Scotsman reports scientists have used neural stem cells to reverse memory loss in mice, which could lead to effective treatments for Alzheimer's Disease:
"BRAIN diseases such as Alzheimer's and strokes could be treated by stem-cell therapy, a study suggests. Scientists have used the technique to repair the damaged memory of mice - and believe it could work in humans. US researchers injected neural stem cells into the brains of mice and after three months they seemed to have matured and made the right connections to reverse the memory deficit. The experiments provide the first evidence that stem cells could reverse cognitive damage lost through strokes, Alzheimer's and other neurodegenerative diseases."
Injecting stem cells sparks progress in repairing heart
Source: USA Today
Posted: November 7, 2007 9:30 PM EST
Summary:
USA Today reports on new findings that muscle stem cells can improve heart function after a heart attack:
"Researchers from Finland and California showed it is possible to inject heart attack patients with muscle stem cells and boost their hearts' pumping power. The studies, though preliminary, are the latest of several to open a window into the future of heart attack care."
Posted: November 7, 2007 9:30 PM EST
Summary:
USA Today reports on new findings that muscle stem cells can improve heart function after a heart attack:
"Researchers from Finland and California showed it is possible to inject heart attack patients with muscle stem cells and boost their hearts' pumping power. The studies, though preliminary, are the latest of several to open a window into the future of heart attack care."
Stem Cells Show Early Promise for Heart Problems
Source: HealthDay News
Date: November 7, 2007
Summary:
HealthDay News reports on news studies using adult stem cells to treat heart damage resulting from heart attacks
"Scientists are edging toward a better understanding of how stem cells might one day restore function to damaged hearts. One study found that patients' own stem cells, when injected into the heart after treatment for a heart attack, improved the heart's ability to pump effectively. But this finding is fairly preliminary."
Date: November 7, 2007
Summary:
HealthDay News reports on news studies using adult stem cells to treat heart damage resulting from heart attacks
"Scientists are edging toward a better understanding of how stem cells might one day restore function to damaged hearts. One study found that patients' own stem cells, when injected into the heart after treatment for a heart attack, improved the heart's ability to pump effectively. But this finding is fairly preliminary."
Researchers uncover gene's role in type 1 diabetes
Source: University of Virginia Health System
Date: November 7, 2007
Summary:
Researchers at the University of Virginia Health System have identified an enzyme thought to be an important instigator of the inner-body conflict that causes Type 1 diabetes. A chronic condition that affects nearly three million American children and adults, Type 1 diabetes is more severe than Type 2. Type 1 diabetes, also called autoimmune diabetes, arises when the body’s infection-fighting white blood cells start destroying the beta-cells that produce insulin in the pancreas.
Date: November 7, 2007
Summary:
Researchers at the University of Virginia Health System have identified an enzyme thought to be an important instigator of the inner-body conflict that causes Type 1 diabetes. A chronic condition that affects nearly three million American children and adults, Type 1 diabetes is more severe than Type 2. Type 1 diabetes, also called autoimmune diabetes, arises when the body’s infection-fighting white blood cells start destroying the beta-cells that produce insulin in the pancreas.
Sangamo BioSciences Announces ZFP Therapeutic Data From Nerve Regeneration Program at Society for Neuroscience Meeting
Source: Sangamo BioSciences, Inc.
Date: November 7, 2007
Summary:
Sangamo BioSciences, Inc. announced today the presentation of preclinical data from its ZFP Therapeutic(TM) program in nerve regeneration at Neuroscience 2007, the 37th Annual Meeting of the Society for Neuroscience. A statistically significant effect on both recovery of hind-limb function and spinal cord tissue preservation was demonstrated in a severe model of spinal cord injury (SCI) following treatment at the time of injury with a zinc finger DNA-binding protein activator of vascular endothelial growth factor (VEGF ZFP TF).
Date: November 7, 2007
Summary:
Sangamo BioSciences, Inc. announced today the presentation of preclinical data from its ZFP Therapeutic(TM) program in nerve regeneration at Neuroscience 2007, the 37th Annual Meeting of the Society for Neuroscience. A statistically significant effect on both recovery of hind-limb function and spinal cord tissue preservation was demonstrated in a severe model of spinal cord injury (SCI) following treatment at the time of injury with a zinc finger DNA-binding protein activator of vascular endothelial growth factor (VEGF ZFP TF).
Data Show Geron's Cell-Based Therapeutic for Spinal Cord Injury Survives and Exhibits Remyelination for at Least Nine Months Following Injection
Source: Geron Corporation
Posted: November 7, 2007 7:30 am ET
Summary:
In an official company news release, Geron Corporation, a biotechnology company in the field of stem cell research, reported its embryonic stem cell therapy to treat spinal cord injury regenerated parts of spinal cord nerve coating tissue in rats called myelin:
"Geron Corporation today announced that data show GRNOPC1, the company’s human embryonic stem cell (hESC)-based therapeutic for spinal cord injury, survives and exhibits durable and robust human remyelination in spinal cord-injured rats for at least nine months following a single injection. The data also demonstrate that GRNOPC1 does not amplify neuropathic pain or the reaction to painful stimuli. This finding is in contrast to research that shows many other cell types, when injected into the spinal cord, amplify neuropathic pain, a common long-term complication of spinal cord injury in man."
Posted: November 7, 2007 7:30 am ET
Summary:
In an official company news release, Geron Corporation, a biotechnology company in the field of stem cell research, reported its embryonic stem cell therapy to treat spinal cord injury regenerated parts of spinal cord nerve coating tissue in rats called myelin:
"Geron Corporation today announced that data show GRNOPC1, the company’s human embryonic stem cell (hESC)-based therapeutic for spinal cord injury, survives and exhibits durable and robust human remyelination in spinal cord-injured rats for at least nine months following a single injection. The data also demonstrate that GRNOPC1 does not amplify neuropathic pain or the reaction to painful stimuli. This finding is in contrast to research that shows many other cell types, when injected into the spinal cord, amplify neuropathic pain, a common long-term complication of spinal cord injury in man."
Tuesday, November 06, 2007
Fat cells send message that aids insulin secretion
Source: Washington University School of Medicine.
Date: November 6, 2007
Summary:
The body's fat cells help the pancreas do its job of secreting insulin, according to new research. This previously unrecognized process ultimately could lead to new methods to improve glucose metabolism in type 2 diabetic or insulin-resistant people. In a study using laboratory mice, published in the November 7, 2007 issue of Cell Metabolism, scientists at the Washington University School of Medicine report that fat cells release a protein that aids insulin secretion from pancreatic beta cells, which are the sole source of insulin. The protein is an enzyme that the pancreatic cells themselves produce in only minimal amounts. The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells.
Date: November 6, 2007
Summary:
The body's fat cells help the pancreas do its job of secreting insulin, according to new research. This previously unrecognized process ultimately could lead to new methods to improve glucose metabolism in type 2 diabetic or insulin-resistant people. In a study using laboratory mice, published in the November 7, 2007 issue of Cell Metabolism, scientists at the Washington University School of Medicine report that fat cells release a protein that aids insulin secretion from pancreatic beta cells, which are the sole source of insulin. The protein is an enzyme that the pancreatic cells themselves produce in only minimal amounts. The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells.
Monday, November 05, 2007
Pioneering mini cell transplants for cancer patients will save lives, say doctors
Source: Daily Mail - UK
Last updated at 19:51pm on 5th November 2007
Summary:
The Daily Mail reports on a new cell transplant procedure to treat cancer patients:
"Cancer sufferers are being given pioneering mini cell transplants that "reverse" conventional treatment. The ground-breaking procedure uses stem cells taken from donor blood, making it safer and faster for patients. ...low doses of chemotherapy stun tumour cells into submission for a short period of time, while injections of donor stem cells can take hold within the body and multiply. The transplanted cells then take up the battle against the cancer. The technique also removes the need for donors to undergo an operation to extract the bone marrow which contains stem cells.'
Last updated at 19:51pm on 5th November 2007
Summary:
The Daily Mail reports on a new cell transplant procedure to treat cancer patients:
"Cancer sufferers are being given pioneering mini cell transplants that "reverse" conventional treatment. The ground-breaking procedure uses stem cells taken from donor blood, making it safer and faster for patients. ...low doses of chemotherapy stun tumour cells into submission for a short period of time, while injections of donor stem cells can take hold within the body and multiply. The transplanted cells then take up the battle against the cancer. The technique also removes the need for donors to undergo an operation to extract the bone marrow which contains stem cells.'
New stem cell delivery system is developed
Source: United Press International
Published: November 5, 2007 at 4:27 PM EST
Summary:
A new neural stem cell drug delivery system has been created by U.S. scientists to fight Hunter syndrome and ultimately a variety of genetic disorders.
Published: November 5, 2007 at 4:27 PM EST
Summary:
A new neural stem cell drug delivery system has been created by U.S. scientists to fight Hunter syndrome and ultimately a variety of genetic disorders.
New Clinical Trials Could Open 'Golden Era' In Spinal Cord Injury And ALS Research
Source: Society For Neuroscience
Date: November 5, 2007
Summary:
New experimental therapies are being -- or soon may be -- tested in clinical trials that could open the doors to a "golden era" for research to improve the treatments of people with spinal cord injuries, brain injuries, stroke, and other severe movement disorders, scientists say.
Date: November 5, 2007
Summary:
New experimental therapies are being -- or soon may be -- tested in clinical trials that could open the doors to a "golden era" for research to improve the treatments of people with spinal cord injuries, brain injuries, stroke, and other severe movement disorders, scientists say.
New research reveals critical knowledge about the nervous system
Source: Rutgers University
Date: November 5, 2007
Summary:
Uncover the neural communication links involved in myelination, the process of protecting a nerve’s axon, and it may become possible to reverse the breakdown of the nervous system’s electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system.
Date: November 5, 2007
Summary:
Uncover the neural communication links involved in myelination, the process of protecting a nerve’s axon, and it may become possible to reverse the breakdown of the nervous system’s electrical transmissions in such disorders as multiple sclerosis, spinal cord injuries, diabetes and cancers of the nervous system.
Researchers discover 'instruction manual' that tells cancers how to hide from immune system
Source: University of British Columbia
Date: November 5, 2007
Summary:
A mechanism that creates an “invisibility cloak” for certain cancer cells and allows them to hide from the immune system has been uncovered by a team of researchers at the University of British Columbia.
Date: November 5, 2007
Summary:
A mechanism that creates an “invisibility cloak” for certain cancer cells and allows them to hide from the immune system has been uncovered by a team of researchers at the University of British Columbia.
Sunday, November 04, 2007
Researchers they've taken a step forward in stem cell transplants
Source: The Canadian Press
Posted: November 4, 2007 5:00 PM EST
Summary:
Scientists at Toronto's Hospital for Sick Children say they've taken a step forward in stem cell transplant research. They say they've discovered a gene with properties that allow for successful transfer of stem cells from human bone marrow into mice. They also identified the type of cell that expresses the gene (called SIRPalpha) and is responsible for either destroying or supporting growth of human blood stem cells.
Posted: November 4, 2007 5:00 PM EST
Summary:
Scientists at Toronto's Hospital for Sick Children say they've taken a step forward in stem cell transplant research. They say they've discovered a gene with properties that allow for successful transfer of stem cells from human bone marrow into mice. They also identified the type of cell that expresses the gene (called SIRPalpha) and is responsible for either destroying or supporting growth of human blood stem cells.
New Territory Mapped in Stem Cell Transplantation
Source: The Hospital for Sick Children
Date: November 4, 2007
Summary:
Transplant research has taken another step forward at The Hospital for Sick Children (SickKids) where scientists have
discovered a gene with properties that allow for the successful engraftment of stem cells from human bone marrow into mice. Researchers hope further studies will lead to the development of a therapy so more children with blood diseases can receive bone marrow transplantation.
Date: November 4, 2007
Summary:
Transplant research has taken another step forward at The Hospital for Sick Children (SickKids) where scientists have
discovered a gene with properties that allow for the successful engraftment of stem cells from human bone marrow into mice. Researchers hope further studies will lead to the development of a therapy so more children with blood diseases can receive bone marrow transplantation.
Scientists map gene flaws linked to lung cancer
Source: Agence France Presse (AFP)
Posted: Nov 4, 2007 4:03 PM ET
Summary:
Scientists have mapped the genetic aberrations underlying lung cancer and discovered a gene that plays a critical role in spreading the deadly disease, according to a study
Posted: Nov 4, 2007 4:03 PM ET
Summary:
Scientists have mapped the genetic aberrations underlying lung cancer and discovered a gene that plays a critical role in spreading the deadly disease, according to a study
Sweep of lung cancer genome reveals new gene
Source: Reuters
Posted: November 4, 2007 12:46pm EST
Summary:
An effort to map the genetic landscape of lung cancer has turned up a host of new genes, including one that controls the growth of cells essential for lung function, an international team of researchers said
Posted: November 4, 2007 12:46pm EST
Summary:
An effort to map the genetic landscape of lung cancer has turned up a host of new genes, including one that controls the growth of cells essential for lung function, an international team of researchers said
Saturday, November 03, 2007
Transplant key to success in diabetes cure
Source: Melbourne Herald Sun, Australia
Posted: November 04, 2007 12:00am AST
Summary:
MELBOURNE scientists claim they are just days from conducting a pioneering therapy that will effectively cure Type-1 diabetes. They are set to transplant insulin-producing cells from healthy donor tissue into a diabetic - removing the need for daily insulin injections. Researchers at St Vincent's Institute say the procedure will help the patient produce insulin naturally.
Posted: November 04, 2007 12:00am AST
Summary:
MELBOURNE scientists claim they are just days from conducting a pioneering therapy that will effectively cure Type-1 diabetes. They are set to transplant insulin-producing cells from healthy donor tissue into a diabetic - removing the need for daily insulin injections. Researchers at St Vincent's Institute say the procedure will help the patient produce insulin naturally.
Friday, November 02, 2007
Stem Cells May Restore Memory after Brain Damage
Source: Journal of Neuroscience / Ivanhoe Newswire
Date: November 2, 2007
Summary:
Ivanhoe Newswire reports that a study published in the Journal of Neuroscience revealed that a stem cell treatment restored memory in mice with brain injuries:
"Stem cells may help reverse a persons memory loss after they’ve had a brain injury. A new study from the University of California Irvine looked at mice with brain injuries. It finds the memory of the mice was restored to a similar level found in healthy mice after they got a stem cell treatment for up to three months. Researchers believe the stem cells secrete proteins called neurotrophins that protect vulnerable cells from dying, thereby saving the memory."
Date: November 2, 2007
Summary:
Ivanhoe Newswire reports that a study published in the Journal of Neuroscience revealed that a stem cell treatment restored memory in mice with brain injuries:
"Stem cells may help reverse a persons memory loss after they’ve had a brain injury. A new study from the University of California Irvine looked at mice with brain injuries. It finds the memory of the mice was restored to a similar level found in healthy mice after they got a stem cell treatment for up to three months. Researchers believe the stem cells secrete proteins called neurotrophins that protect vulnerable cells from dying, thereby saving the memory."
Doctors use stem cell therapy for genetic skin disease
Source: University of Minnesota
Date: November 2, 2007
Summary:
University of Minnesota Children's Hospital, Fairview doctors have performed the first bone marrow and cord blood transplant to treat recessive dystrophic epidermolysis bullosa. Children with RDEB lack a protein that anchors skin to the body, resulting in fragile skin that sloughs off with little movement or friction. They suffer painful wounds and must be bandaged at all times to protect their skin from further damage and infection.
Date: November 2, 2007
Summary:
University of Minnesota Children's Hospital, Fairview doctors have performed the first bone marrow and cord blood transplant to treat recessive dystrophic epidermolysis bullosa. Children with RDEB lack a protein that anchors skin to the body, resulting in fragile skin that sloughs off with little movement or friction. They suffer painful wounds and must be bandaged at all times to protect their skin from further damage and infection.
Carnegie Mellon researchers to develop new drug delivery system
Source: Carnegie Mellon University
Date: November 2, 2007
Summary:
Scientists at Carnegie Mellon University are using adult neural stem cells to develop a new stem-based drug delivery therapy that may ultimately help treat a variety of inherited disorders like Hunter syndrome. They are creating genetically engineered adult neural stem cells for delivery to patients' brains, where they will be programmed to produce an essential missing protein.
Date: November 2, 2007
Summary:
Scientists at Carnegie Mellon University are using adult neural stem cells to develop a new stem-based drug delivery therapy that may ultimately help treat a variety of inherited disorders like Hunter syndrome. They are creating genetically engineered adult neural stem cells for delivery to patients' brains, where they will be programmed to produce an essential missing protein.
Scientists discover protein cue that allows limb regrowth in newts
Source: Agence France Presse (AFP)
Posted: November 2, 2007 12:39 EST
Summary:
Scientists have discovered a protein's molecular signal that apparently plays a key role in allowing newts -- which are amphibians -- to regrow severed limbs, a report in the journal Science said Friday. The finding could provide insights in the field of regenerative medicine relating to mammals and humans, said researchers at the University College London (UCL).
Posted: November 2, 2007 12:39 EST
Summary:
Scientists have discovered a protein's molecular signal that apparently plays a key role in allowing newts -- which are amphibians -- to regrow severed limbs, a report in the journal Science said Friday. The finding could provide insights in the field of regenerative medicine relating to mammals and humans, said researchers at the University College London (UCL).
Newts 'may help humans to regenerate limbs'
Source: Daily Mail - UK
Posted: Last updated at 10:03am on 2nd November 2007
Summary:
British scientists have found a key protein that helps newts regrow severed limbs and may guide future research into human regenerative medicine.
Posted: Last updated at 10:03am on 2nd November 2007
Summary:
British scientists have found a key protein that helps newts regrow severed limbs and may guide future research into human regenerative medicine.
Thursday, November 01, 2007
Limb regrowth a step closer after 'regenerative medicine' breakthrough
Source: Daily Telegraph
Last Updated: 7:01pm GMT 01/11/2007
Summary:
The Daily Telegraph reports British scientists have gained insights into how newts regenerate limbs, potentially also enabling human limb regeneration in the future:
"Scientists have taken another step towards the dream of devising a potion that can regenerate digits and lost limbs without scarring. Today, a British team reports the discovery of a molecular signal that allows newts to re-grow a body part if it fails, is severed or is damaged. The discovery of how newts can regenerate their limbs - and their hearts, eyes and jaws - gives Prof Jeremy Brockes of University College London new hope that it could one day be possible to do the same in people."
Last Updated: 7:01pm GMT 01/11/2007
Summary:
The Daily Telegraph reports British scientists have gained insights into how newts regenerate limbs, potentially also enabling human limb regeneration in the future:
"Scientists have taken another step towards the dream of devising a potion that can regenerate digits and lost limbs without scarring. Today, a British team reports the discovery of a molecular signal that allows newts to re-grow a body part if it fails, is severed or is damaged. The discovery of how newts can regenerate their limbs - and their hearts, eyes and jaws - gives Prof Jeremy Brockes of University College London new hope that it could one day be possible to do the same in people."
Bystander Stem Cells Keep Original Neurons Humming
Source: Scientific American
Date: November 1, 2007
Summary:
Scientific American reports stem cells restored memory and learning abilities in mice:
"A new study finds that neural stem cells may be able to save dying brain cells without transforming into new brain tissue, at least in rodents. Researchers from the University of California, Irvine, report that stem cells rejuvenated the learning and memory abilities of mice engineered to lose neurons in a way that simulated the aftermath of Alzheimer's disease, stroke and other brain injuries."
Date: November 1, 2007
Summary:
Scientific American reports stem cells restored memory and learning abilities in mice:
"A new study finds that neural stem cells may be able to save dying brain cells without transforming into new brain tissue, at least in rodents. Researchers from the University of California, Irvine, report that stem cells rejuvenated the learning and memory abilities of mice engineered to lose neurons in a way that simulated the aftermath of Alzheimer's disease, stroke and other brain injuries."
Newt protein may offer clues for human regeneration
Source: Reuters
Posted: November 1, 2007 3:01pm EDT
Summary:
Scientists have found a key protein that helps newts regrow severed limbs and which may guide future research into human regenerative medicine. Biologists have long been intrigued by the ability of newts and salamanders to renew damaged body parts. But how they do it has been unclear.
Posted: November 1, 2007 3:01pm EDT
Summary:
Scientists have found a key protein that helps newts regrow severed limbs and which may guide future research into human regenerative medicine. Biologists have long been intrigued by the ability of newts and salamanders to renew damaged body parts. But how they do it has been unclear.
How Salamanders Sprout New Limbs
Source: LiveScience
Posted: 01 November 2007 02:04 pm ET
Summary:
Limb loss for a salamander is nothing to get up in arms about—they just re-grow a new one. But how? One molecule could be behind their remarkable limb-sprouting ability, according to a new study that could also grow the field of human regenerative medicine.
Posted: 01 November 2007 02:04 pm ET
Summary:
Limb loss for a salamander is nothing to get up in arms about—they just re-grow a new one. But how? One molecule could be behind their remarkable limb-sprouting ability, according to a new study that could also grow the field of human regenerative medicine.
Spinal Stem Cells Offer Hope Against Back Pain
Source: HealthDay News
Date: November 1, 2007
Summary:
HealthDay News reports a discovery of stem cells in the human spine that could repair spinal discs and treat back pain:
"For the first time, researchers have found stem cells within the intervertebral discs of the human spine. They say it may someday be possible to use these stem cells to help repair degenerating discs in order to treat neck and lower back pain."
Date: November 1, 2007
Summary:
HealthDay News reports a discovery of stem cells in the human spine that could repair spinal discs and treat back pain:
"For the first time, researchers have found stem cells within the intervertebral discs of the human spine. They say it may someday be possible to use these stem cells to help repair degenerating discs in order to treat neck and lower back pain."
Jefferson researchers find stem cells in degenerating spinal discs, potential for repair
Source: Thomas Jefferson University
Date: November 1, 2007
Summary:
Orthopedic researchers at Jefferson Medical College have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain.
Date: November 1, 2007
Summary:
Orthopedic researchers at Jefferson Medical College have for the first time found stem cells in the intervertebral discs of the human spine, suggesting that such cells might someday be used to help repair degenerating discs and remedy lower back and neck pain.
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