Thursday, March 23, 2006

Mouse study advances transplant-free approach to Type 1 diabetes

By Eric Hand
ST. LOUIS POST-DISPATCH
Thursday, Mar. 23 2006

Washington University researchers have reaffirmed a simple approach to curing Type 1 diabetes in mice: stop the immune system before it kills off all the insulin-producing cells in the pancreas. The study advances a transplant-free approach to curing Type 1 diabetes with a simple, short and cheap regimen of drugs. But the researchers, who also added adult stem cells from the spleen into the mouse pancreas, did not find spleen cells morphing into a new source of new pancreatic cells, as was claimed by Harvard University researchers three years ago.

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