Sunday, January 28, 2007

Gene knockouts reveal FoxOs' vital functions in cancer defense, health of stem cells

Source: Dana-Farber Cancer Institute
Date: January 26, 2007

Summary:

A team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy. The discoveries reveal potential new targets for cancer drugs and could further research on stem-cell based therapies for degenerative diseases, said researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital, who are jointly publishing two reports in the Jan. 26 issue of Cell.

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