Thursday, April 10, 2008

Developing cancer treatments directed at critical developmental pathway

Source: University of Pennsylvania
Date: April 10, 2008

Summary:

Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. The findings appear this week in Cell Stem Cell, and indicate that inhibitors of Notch may not affect bone marrow stem cells.