Monday, July 21, 2008

Predicting Acute GVHD By Gene Expression Could Improve Liver Stem Cell Transplant Outcomes

Source: Cell Transplantation: The Regenerative Medicine Journal
Date: July 21, 2008

Summary:

Acute graft-versus-host disease occurs when an immune response is elicited by the grafted cells against a recipient, resulting in tissue damage for the treated individual. There are no definitive markers for predicting the development or progression of GVHD following the transplant of allogenic stem cells as therapy for liver cancer. This study offers a preliminary "molecular signature" for the development of acute GVHD based on altered gene expression.