Tuesday, August 19, 2008

Clinical-Scale Generation of Functional Red Blood Cells from Human Embryonic Stem Cells

Source: Advanced Cell Technology, Inc.
Posted: August 19, 2008 3:09 pm ET

Summary:

In an official news release, Advanced Cell Technology, Inc., a biotechology company in the field of stem cell research, reports it has generated red blood cells from human embryonic stem cells:

" Advanced Cell Technology, Inc. (“ACT”) (OTC: ACTC.PK) reported that it is feasible to differentiate and mature human embryonic stem cells (hESCs) into functional oxygen-carrying red blood cells (RBCs) under conditions suitable for scale-up. The research, which appears online (pre-published ahead of print) in the journal Blood –the leading publication in the field—by ACTC and its collaborators at the Mayo Clinic and the University of Illinois, shows for the first time that the oxygen-carrying capacity of hESC-derived blood cells is comparable to normal transfusable RBCs, and that the cells respond to biochemical changes in a physiologically effective manner."