Source: Scripps Research Institute
Date: November 3, 2010
Summary:
As babies grow, their brain cells develop from a pool of stem cells—some stem cells continuously divide, replenishing the pool, whereas others morph into mature functioning nerve cells. Now researchers at The Scripps Research Institute have shown that as the newly formed nerve cells start firing electrical signals, this activity slows down stem cell division, emptying out the stem cell pool in favor of nerve cell formation.
The study, published in the November 4 issue of the journal Neuron, shows that brain activity controls the balance between stem cells and mature nerve cells and suggests that abnormal brain activity, as it occurs during seizures, may have long-lasting effects on brain development. The results also have implications for replacing brain cells that are damaged or lost through diseases such as Alzheimer's or Parkinson's disease.
