Monday, December 13, 2010

Leukemia: Leukemic Stem Cells Reversed to Pre-Leukemic Stage By Suppressing a Protein

Source: King's College London
Date: 13 December 2010

Summary:

Researchers at King's College London have discovered that leukaemic stem cells can be reversed to a pre-leukaemic stage by suppressing a protein called beta-catenin found in the blood. They also found that advanced leukaemic stem cells that had become resistant to treatment could be 're-sensitised' to treatment by suppressing the same protein.

Professor Eric So, who led the study at the Department of Haematology at King's College London, says the findings, published December 13 in the journal Cancer Cell, represent a 'critical step forward' in the search for more effective treatments for aggressive forms of leukaemia.