Wednesday, November 23, 2011

Key to Aging? Key Molecular Switch for Telomere Extension by Telomerase Identified

Source: University of Illinois at Chicago
Date: November 23, 2011

Summary:

Researchers at the University of Illinois at Chicago College of Medicine describe for the first time a key target of DNA damage checkpoint enzymes that must be chemically modified to enable stable maintenance of chromosome ends by telomerase, an enzyme thought to play a key role in cancer and aging. Their findings are reported online in Nature Structural and Molecular Biology.