Thursday, April 26, 2012

Growing up a neural stem cell: The importance of clinging together and then letting go

Source: University of California - Los Angeles
Date: April 26, 2012

Summary:

Stem cell researchers at UCLA have identified new components of the genetic pathway that controls the adhesive properties and proliferation of neural stem cells and the formation of neurons in early development.

The finding by scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA could be important because errors in this pathway can lead to a variety of birth defects that affect the structure of the nervous system, as well as more subtle changes that impair cognitive and motor functions associated with disorders such as autism.

The results of the four-year study are published April 26 in the peer-reviewed journal Neuron.