Friday, June 30, 2006

Key Molecule Puts Brakes on Stem-Cell Differentiation

Source: Howard Hughes Medical Institute
Posted: June 30, 2006

Summary:

Howard Hughes Medical Institute researchers have identified a protein that could aid development of methods to grow new skin to treat patients with burns or skin ulcers. The protein maintains hair follicle stem cells in their immature, undifferentiated state. The findings, published June 30, 2006 in the journal Science also offer a new perspective on how stem cells are regulated to keep them from differentiating prematurely. The studies could improve the quality and function of stem cells treat burns and chronic skin ulcers.

Commentary: Maybe this advance in understanding cell differentiation will eventually enable researchers to transform embryonic stem cells into specialized cells that will function effectively to treat diseases, injuries and conditions.

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