Friday, June 16, 2006

New Roles For Growth Factors: Enticing Nerve Cells To Muscles

Source: Salk Institute
Posted: June 16, 2006

Summary:

La Jolla, CA - During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target. While several recent studies discovered molecules that repel motor neuron axons from incorrect targets in the limb, scientists at the Salk Institute for Biological Studies have identified a molecule, known as FGF, that actively lures growing axons closer to the right destination. Their findings appear in the June 15 issue of Neuron.

Commentary: Hopefully this finding will enable nerve cells to reach their intended location-the site of injury or disease-and effectively treat the injury or disease.

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