Gene Involved In Common Birth Defect Also Regulates Skin Biology

Source: University of Iowa
Date: October 16, 2006

Summary:

Following up on an earlier discovery that a gene called IRF6 is involved in the common birth defect cleft lip and palate, researchers at the University of Iowa Roy J. and Lucille A. Carver College of Medicine and their colleagues have identified the function of the gene. Their latest findings, published online Oct. 15 in Nature Genetics, reveal an unexpected role for IRF6 in the growth and development of skin cells, a discovery that may have implications for wound healing and cancer research.

Commentary: Maybe this discovery will eventually enable researchers to regenerate human tissues that have been injured by wounds or destroyed by diseases.