Monday, July 23, 2007

Effects of aging in stem cells

Source: Public Library of Science
Date: July 23, 2007

Summary:

Age-related defects in stem cells can limit proper tissue maintenance and hence contribute to a shortened lifespan. There is little disagreement that the body’s maintenance and repair systems deteriorate with age, even as there is plenty of disagreement as to why. Stem cells combat the aging process by replenishing old or damaged cells—particularly in the skin, gut, and blood—with a fresh supply to maintain and repair tissue. Unfortunately, new evidence from the open-access journal
  • PLoS Biology and also published by
  • EurekaAlert and
  • Medical News Today, suggests that this regenerative capacity also declines with age as stem cells acquire functional defects.