Wednesday, July 18, 2007

Immune cells in the brains of aging mice prove more functional than expected

Source: Rockefeller University
Posted: July 18, 2007

Summary:

As people age past 50, their brains begin to decrease in mass. But even as neurons shrink, other brain cells appear to become more active. Microglia — the small immune cells that sense injury and the presence of pathogens in the nervous system — have shown increased activity, producing higher amounts of signaling molecules called cytokines and leading researchers to suggest that these cells may become dysfunctional as our brains get older. Because higher levels of cytokines have been associated with neurodegenerative diseases, scientists are paying close attention to the role of microglia in these disorders.