Source: Yale University
Date: October 25, 2007
Summary:
A study by researchers at the Yale Stem Cell Center for the first time demonstrates that piRNAs, a recently discovered class of tiny RNAs, play an important role in controlling gene function, it was reported this week in Nature. Haifan Lin, director of the stem cell center and professor of cell biology at Yale School of Medicine, heads the laboratory that originally identified piRNAs. Derived mostly from so-called "junk DNA," piRNAs had escaped the attention of generations of geneticists and molecular biologists until last year when Lin's team discovered them in mammalian reproductive cells, and named them. The lab's current work suggests that piRNAs have crucial functions in controlling stem cell fate and other processes of tissue development.
