Sunday, October 19, 2008

Swamping Bad Cells With Good In ALS Animal Models Helps Sustain Breathing

Source: Johns Hopkins Medical Institutions
Date: October 19, 2008

Summary:

Johns Hopkins researchers report that transplanting a new line of stem cell-like cells into rat models of the disease clearly shifts key signs of neurodegenerative disease in general and ALS in particular - slowing the animals' neuron loss and extending life. The new work supports the hypothesis that artificially outnumbering unhealthy cells with healthy ones in targeted parts of the spinal cord preserves limb strength and breathing and can increase survival. An account of the work appears online in Nature Neuroscience.