Wednesday, July 01, 2009

Blood stem cell growth factor reverses memory decline in mice

Source: University of South Florida Health
Date: July 1, 2009

Summary:

A human growth factor that stimulates blood stem cells to proliferate in the bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, researchers at the University of South Florida and James A. Haley Hospital found. The granulocyte-colony stimulating factor (GCSF) significantly reduced levels of the brain-clogging protein beta amyloid deposited in excess in the brains of the Alzheimer's mice, increased the production of new neurons and promoted nerve cell connections. The findings are reported online in Neuroscience and are scheduled to appear in the journal's print edition in August.