Thursday, May 06, 2010

Endometrial Stem Cells Restore Brain Dopamine Levels. Mouse Study May Lead to New Therapies for Parkinson’s Disease

Source: National Institute of Child Health and Human Development (NICHD)
Date: May 6, 2010

Summary:

Endometrial stem cells injected into the brains of mice with a laboratory-induced form of Parkinson’s disease appeared to take over the functioning of brain cells eradicated by the disease. The finding raises the possibility that women with Parkinson’s disease could serve as their own stem cell donors. Similarly, because endometrial stem cells are readily available and easy to collect, banks of endometrial stem cells could be stored for men and women with Parkinson’s disease.

This is the first time that researchers have successfully transplanted stem cells derived from the endometrium, or the lining of the uterus, into another kind of tissue (the brain) and shown that these cells can develop into cells with the properties of that tissue. The findings appear online in the Journal of Cellular and Molecular Medicine.