Thursday, May 06, 2010

New nerve cells - even in old age Max Planck researchers find different types of stem cells in the brains of mature and old mice

Source: Max Planck Society
Date: May 6, 2010

Summary:

After birth the brain looses many nerve cells and this continues throughout life - most neurons are formed before birth, after which many excess neurons degenerate. However, there are some cells that are still capable of division in old age - in the brains of mice, at least. According to scientists from the Max Planck Institute of Immunobiology in Freiburg, different types of neuronal stem cells exist that can create new neurons. While they divide continuously and create new neurons in young animals, a large proportion of the cells in older animals persist in a state of dormancy. However, the production of new cells can be reactivated, for example, through physical activity or epileptic seizures. What happens in mice could also be applicable to humans as neurons that are capable of dividing also occur in the human brain into adulthood. The research is reported in the current issue of Cell Stem Cell.