Friday, June 25, 2010

Ronin recruits protein allies to sustain embryonic stem cell growth

Source: Baylor College of Medicine
Date: June 25, 2010

Summary:

Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene "program" that stimulates growth of the stem cells and may even play a role in cancer, said a group of researchers led by Baylor College of Medicine in a current report in the journal Genes and Development.