Tuesday, September 28, 2010

'Firefly' Stem Cells May Repair Damaged Hearts

Source: University of Central Florida
Date: September 28, 2010

Summary:

Stem cells that glow like fireflies could someday help doctors heal damaged hearts without cutting into patients' chests. In his University of Central Florida lab, Steven Ebert engineered stem cells with the same enzyme that makes fireflies glow. The "firefly" stem cells glow brighter and brighter as they develop into healthy heart muscle, allowing doctors to track whether and where the stem cells are working.

If doctors can figure out exactly how the cells repair and regenerate cardiac tissue, stem cell therapies could offer hope to more than 17.6 million Americans who suffer from coronary disease. The glow of the enzyme also means therapies would no longer require cutting into patients' chest cavities to monitor the healing. The study, funded by the National Institutes of Health and the American Heart Association, is a featured cover story in this month's highly ranked Stem Cells and Development Journal.