Monday, September 06, 2010

Induced Pluripotent Stem Cell Retain an Inactivated X Chromosome, Study Finds

Source: University of California - Los Angeles
Date: September 6, 2010

Summary:

Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at University of California Los Angeles have found. The finding, reported in the journal Cell Stem Cell, could have implications for studying X chromosome-linked diseases such as Rett syndrome, caused by mutations in a gene located on the X chromosome.