Tuesday, January 18, 2011

Mother’s stem cells likely key to treating genetic disease before birth

Source: University of California - San Francisco
Date: January 18, 2011

Summary:

University of California, San Francisco researchers have tackled a decade-long scientific conundrum, and their discovery is expected to lead to significant advances in using stem cells to treat genetic diseases before birth. Through a series of mouse model experiments, the research team determined that a mother’s immune response prevents a fetus from accepting transplanted blood stem cells, and yet this response can be overcome simply by transplanting cells harvested from the mother herself. Findings from the study appear online in The Journal of Clinical Investigation.