Thursday, May 05, 2011

Normal stem cells made to look and act like cancer stem cells

Source: University of North Carolina at Chapel Hill School of Medicine
Date: May 5, 2011

Summary:

CHAPEL HILL, NC — Researchers at the University of North Carolina at Chapel Hill School of Medicine, after isolating normal stem cells that form the developing placenta, have given them the same properties of stem cells associated with an aggressive type of breast cancer.

The scientific first opens the door for developing novel targeted therapies aimed at triple negative breast cancer. Known also as TNBC, this is a highly recurrent tumor that spreads aggressively beyond its original site in the breast and carries a poor prognosis for patients who have it. The study will be published online Friday, May 6, by the journal Cell Stem Cell.