Thursday, May 12, 2011

Pluripotent adult stem cells power planarian regeneration

Source: Whitehead Institute for Biomedical Research
Date: May 12, 2011

Summary:

Researchers at the Whitehead Institute for Biomedical Research have determined that the planarian flatworm regenerates missing tissues by using pluripotent adult stem cells. Until now, scientists could not determine whether the dividing cells in planarians, called neoblasts, are a mixture of specialized stem cells that each regenerates specific tissues, or if individual neoblasts are pluripotent and able to regenerate all tissues. Using complementary methods, the researchers demonstrated that adult planarians not only possess pluripotent stem cells -- known as clonogenic neoblasts (cNeoblasts) -- but that a single such cell is capable of regenerating an entire animal. Their results are published in the May 13 issue of Science.