Monday, October 31, 2011

Researchers Find Regulatory T-Cell Clue To Help Prevent Graft-Versus-Host Disease

Source: H. Lee Moffitt Cancer Center & Research Institute
Date: October 31, 2011

Summary:


TAMPA, Fla. - Graft-versus-host disease (GVHD) is a serious risk in many kinds of cell transplants, including for stem cell transplants carried out when stem cells are partially depleted of conventional T cells, which play an important role in the immune system. Now, in a study published in a recent issue of the journal Blood, researchers at Moffitt Cancer Center have tested a process by which T regulatory cells (Tregs) can be "expanded" to help prevent GVHD.