Monday, October 10, 2011

Seeking superior stem cells New technique produces one hundred-fold increase in efficiency in reprogramming human cells

Source: Wellcome Trust Sanger Institute
Date: 10 October 2011

Summary:

Researchers from the Wellcome Trust Sanger Institute have today (07/10/2011) announced a new technique to reprogramme human cells, such as skin cells, into stem cells. Their process increases the efficiency of cell reprogramming by one hundred-fold and generates cells of a higher quality at a faster rate.

Until now cells have been reprogrammed using four specific regulatory proteins. By adding two further regulatory factors, Liu and co-workers brought about a dramatic improvement in the efficiency of reprogramming and the robustness of stem cell development. The new streamlined process produces cells that can grow more easily.

The study is published in the Proceedings of the National Academy of Sciences.