Source: University of Pittsburgh Medical Center
Posted: June 1, 2006
Using a relatively new technology called RNA interference to turn off genes that regulate cell differentiation, researchers have demonstrated they can increase the propensity of muscle-derived stem cells (MDSCs) to become bone-forming cells. Based on these results, the investigators believe that by turning off specific genetic factors they can control the capacity of MDSCs as a means of treating various musculoskeletal diseases and injuries.
Commentary: This finding seems as if it could provide scientist with insights into neuro-muscular diseases could be used as a basis for development of treatments for such diseases.
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