Source: NewScientist.com news service
Posted: 14:33 25 August 2006
Summary:
Researchers have managed to specify the type of cell an adult stem cell will become by altering the stiffness of the material they are grown on. Bone, nerve and muscle cell lines have been selectively initiated from human bone marrow cells by changing the physical consistency of the growth medium. Previous studies have demonstrated that biochemical signalling strongly influences stem cell development. Now, researchers have shown for the first time that in the absence of any chemical signalling, adult bone marrow stems cells will begin to differentiate into unique cell types based solely on how tough the surrounding "tissue" is.
Commentary: Maybe this discovery will enable researchers to transform stem cells into specific body cell types to treat medical conditions, diseases and injuries.
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