Wednesday, September 20, 2006

Study reveals white blood cells can hurt and help transplanted kidneys: Findings could extend life of transplanted kidneys, reduce hospital stays

Source: Johns Hopkins Medical Institutions
Posted: September 20, 2006

Summary:

A new study by researchers at the Johns Hop.kins University School of Medicine revealed that T cells can also play a role in reducing cellular damage in injured kidneys. In the study, designed to try to find these cells and learn more about kidney injury, white blood cells were taken from mice that had undergone experimentally created. These cells were injected into mice engineered without a thymus gland, which produces T cells. A comparison group of genetically engineered mice got no injections. After the researchers temporarily stopped blood flow to kidneys in mice in both groups for 30 minutes, they discovered that the kidneys in the injected mice were improved compared to the other group of mice.

Commentary: Maybe this finding will lead to effective stem cell treatments for patients with kidney damage, injury or failure.

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