Wednesday, September 06, 2006

Switching off Aging in Stem Cells

Source: Howard Hughes Medical Institute
Posted: September 6, 2006

Summary:

Researchers have located a single molecular switch plays a central role in inducing stem cells in the brain, pancreas, and blood to lose function as they age. Mice lacking that switch show considerably reduced aging-related decline in stem cell function and tissue regeneration. While the finding could ultimately lead to drugs to slow or reverse degeneration in the brain and other tissues, the researchers cautioned such treatments would have to be balanced against the chance of increasing cancer risk in patients.

Commentary: Maybe this finding can be translated into effective treatments for age-related diseases and conditions in humans.

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