Source: NewScientist.com news service
Posted: 15 December 2006 17:56 GMT
Summary:
Canadian researchers eliminated type 1 diabetes in diabetes-prone mice by knocking out a set of faulty sensory nerves in the pancreas. Researchers examined the nerves of the mice and compared them with normal mice, they found that the nerves of diabetes-prone mice do not producing enough substance P. This causes islet cells to overproduce insulin, leading to insulin-resistance and eventually islet-cell death. The researchers injected some directly into the pancreas. Symptoms of diabetes were eliminated and the mice remained diabetes-free for weeks, and even months in some cases. Researchers are hopeful that if the same process could work in humans, a single injection could allay symptoms of the disease for years. They also believe the finding could chart a new path in treatment of the disease in humans.
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