Thursday, December 14, 2006

Stem cells get a grip

Source: American Society for Cell Biology
Date: December 14, 2006

Summary:

In real estate, it's location, location, location. In stem cells, it's niche, niche, niche. Stems cells are regulated by "intrinsic factors" but it's also becoming increasingly clear that their "stemness" depends on the unique microenvironment called the stem cell niche. No adult or somatic stem cells have a more complex niche life than hematopoietic stem cells, which give rise to all the different types of blood and immune cells. The bone marrow is their niche.

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