Sunday, December 10, 2006

Detailed 3-D Image Catches A Key Regulator Of Neural Stem Cell Differentiation In Action

Source: Salk Institute
Date: December 10, 2006

Summary:

Researchers at the Salk Institute for Biological Studies in collaboration with scientists at the University of California, San Diego (UCSD) took a high resolution "action shot" of a protein switch that plays a crucial role in the development of the nervous system. A finely tuned network of molecular "on" and "off" switches regulates the differentiation of embryonic stem cells into different tissue types. Being able to manipulate individual switches would allow scientists to nudge embryonic stem cells into becoming specific cell types, a plus for both basic research and potential therapies.