Thursday, January 17, 2008

Discovery of 'creator' gene for cerebral cortex points to potential stem cell treatments

Source: University of California, Irvine
Date: January 17, 2008

Summary:

University of California, Irvine researchers have identified a gene that is specifically responsible for generating the cerebral cortex, a finding that could lead to stem cell therapies to treat brain injuries and diseases such as stroke and Alzheimer’s. Dr. Edwin Monuki, doctoral student Karla Hirokawa and their colleagues in the departments of Pathology & Laboratory Medicine and Developmental & Cell Biology found that a gene called Lhx2 serves as the long-sought cortical "creator" gene that instructs stem cells in the developing brain to form the cerebral cortex.