Source: Salk Institute
Date: January 30, 2008
Summary:
Boosted by physical and mental exercise, neural stem cells continue to sprout new neurons throughout life, but the exact function of these newcomers has been the topic of much debate. Removing a genetic master switch that maintains neural stem cells in their proliferative state finally gave researchers at the Salk Institute for Biological Studies some definitive answers. Without adult neurogenesis — literally the “birth of neurons” —genetically engineered mice turned into “slow learners” that had trouble navigating a water maze and remembering the location of a submerged platform, the Salk investigators report in the Jan. 30 Advance Online Edition of Nature. The findings suggest that, one day, researchers might be able to stimulate neurogenesis with orally active drugs to influence memory function, the researchers say.
